Join Coulibaly lab
Welcome to the Coulibaly Lab! We are continually looking for passionate students and researchers to help us explore the virosphere, discover new tricks that viruses use to subvert their host and design the next generation of antimicrobial strategies.
The laboratory has two major themes suitable for anyone interested in understanding viruses at the highest-resolution scale using advanced structural biology, or motivated by the rational development of new vaccines and drugs to fight specific human pathogens including HIV, HCV and mosquito-borne diseases.
Our approaches range from X-ray crystallography, cryo-electron microscopy to protein engineering at the crossroad between microbiology, biochemistry and immunology.
Whether you want to research, invest, donate or partner with us to accelerate our life-changing discoveries, we'd be delighted to hear from you. We have opportunities for PhD students, post docs and senior researchers to join our lab. Feel free to contact Associate Professor Coulibaly with any queries.
Donate to our lab
The Structural Virology laboratory is proud to have been working with several Foundations with whom we share common values and objectives. Specifically, A/Prof Fasseli Coulibaly would like to thank the commitment and financial support of the Bill & Melinda Gates Foundation, the Australian Centre for HIV and Hepatitis Virology research, and the CASS Foundation. Please get in touch if you’d like to support our research.
We welcome your involvement in any form to continue this work and expand its impact:
The global eradication of the deadly virus smallpox in the 1970s, was the first successful vaccination campaign to rid the world of disease killing one in three. While Polio has almost been eradicated, and the flu vaccine which has largely been effective in preventing epidemics, waves of pandemic (H1N1 flu) and (re)emerging viruses (MERS, Zika, Dengue, Ebola) reminds us of the ongoing threat of viral diseases to human health.
To help tackle this problem we apply our expertise in structural biology to investigate all the steps of viral infection - assembly, replication, virulence – and then use that knowledge to better fight viruses. Much of our work can be applied to different viruses to help build a picture of how they infect and cause disease.
Using our key Vaccine Technology Platform initially designed with support from the Bill & Melinda Gates Foundation, we also hope to help develop new vaccines to target prevalent and emerging viral diseases. Central to our technology is taking advantage of the natural properties of protein crystals formed by a virus that infects insects. The crystals are incredibly stable, even at high temperatures making them ideal candidates for packaging and delivery of antigens isolated from pathogens such as viruses, bacteria or parasites to trigger protective immune responses to help fight off deadly infections.
Selected funding groups
We gratefully acknowledge the funding given to our lab by the following past and current funding by philanthropic foundations:
- Bill & Melinda Gates Foundation
- The Australian Centre for HIV and Hepatitis Virology Research
- The CASS Foundation