Del Borgo Laboratory
Nanopharmacology Lab
Welcome to the Del Borgo Lab
The Nanopharmacology lab centres around using nanotechnology for the design and delivery of macromolecules, in particular, synthetic peptides as drugs. Currently we are focusing on a delivery strategy to afford functional materials that can be tailored for applications in a variety of disease settings.
We're part of the Monash Biomedicine Discovery Institute, and a member of the Cardiovascular Disease and Cancer Programs, and the Department of Pharmacology.
Dr Mark Del Borgo
My global research connections, partners and funding can be viewed on my Monash Research Profile.
If you are a student interested in doing research in our lab, visit Supervisor Connect.
Click the links below to connect with me on Twitter, ORCID, Google Scholar and LinkedIn.
Our research
The ability of peptides to self-assemble through non-covalent interactions spontaneously or in response to specific triggers has been the focus of researchers to build materials that can be applied to a range of applications. This allows for the tailoring of materials through the chemical modification of the peptide building blocks.
Dr Del Borgo discovered that peptides comprised entirely of β3-amino acids self-assemble to form fibrous structures. Since then, the lab has worked tirelessly to further investigate, optimise and control this phenomenon to yield biomaterials that could one day prove useful in a real-world setting. We have created new building blocks that allow us to finely tune the function of our nanomaterials and we have a wide number of ligands that can be attached to the building blocks that will enable the generation of responsive smart materials.
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Drug delivery using injectable β-peptide hydrogels to treat cardiovascular and neurological conditions.
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Encapsulation of stem cells and exosomes within β-peptide hydrogels as novel therapies.
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Lab members
We are committed to excellence in research.
Join Our Lab
We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.