Fletcher and Knoblich lab publications
Selected highlight publications
1. Knoblich K, Cruz Migoni S, Siew SM, Jinks E, Kaul B, Jeffery HC, Baker AT, Suliman M, Vrzalikova K, Mehenna H, Murray PG, Barone F, Oo YH, Newsome PN, Hirschfield G, Kelly D, Lee SP, Parekkadan B, Turley SJ, Fletcher AL. 2018. The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation. PLoS Biol. 16(9):e2005046.
2. Fletcher AL, Acton SE, Knoblich K. 2015. Lymph node fibroblastic reticular cells in health and disease. Nat Rev Immunol. 15:350-361.
3. Fletcher AL, Elman JS, Astarita J, Murray R, Saeidi N, D’Rozario J, Knoblich K, Brown FD, Schildberg FA, Nieves JM, Heng TS, Boyd RL, Turley SJ, Parekkadan B. 2014. Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in highmortality murine sepsis. Sci Transl Med. 6:249ra109
4. Knoblich K, Wang HX, Sharma C, Fletcher AL, Turley SJ, Hemler ME. 2014. Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits -catenin degradation. Cell Mol Life Sci. 71:1305–1314.
5. Malhotra D*, Fletcher AL* (co-first author), Astarita J, Lukacs-Kornek V, Tayalia P, Gonzalez SF, Elpek KG, Chang SK, Knoblich K, Hemler ME, Brenner MB, Carroll MC, Mooney DJ, Turley SJ; Immunological Genome Project Consortium. 2012. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat Immunol. 13:499-510
6. Fletcher AL, Lukacs-Kornek V, Reynoso ED, Pinner SE, Bellemare-Pelletier A, Curry MS, Collier AR, Boyd RL, Turley SJ. 2010. Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med. 207, 689-697