Formosa Laboratory
Monash Biomedicine Discovery Institute

Formosa Group publications

Selected highlight publications

  1. Formosa, L. E.*, Maghool, S.*, Sharpe, A. J., Reljic, B., Muellner-Wong, L., Stroud, D. A., Ryan, M. T. & Maher, M. J. (2022) Mitochondrial COA7 is a heme-binding protein with disulfide reductase activity, which acts in the early stages of complex IV assembly. Proc Natl Acad Sci U S A, 119. *Co-first author PMID: 35210360

  2. Formosa, L. E.†, Reljic, B., Sharpe, A. J., Hock, D. H., Muellner-Wong, L., Stroud, D. A. & Ryan, M. T.† (2021) Optic atrophy–associated TMEM126A is an assembly factor for the ND4-module of mitochondrial complex I. Proceedings of the National Academy of Sciences, 118, e2019665118. †Co-corresponding author PMID: 33879611

  3. Formosa, L. E.†, Muellner-Wong, L., Reljic, B., Sharpe, A. J., Jackson, T. D., Beilharz, T. H., Stojanovski, D., Lazarou, M., Stroud, D. A. & Ryan, M. T. † (2020) Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I. Cell Rep, 31, 107541. †Co-corresponding author PMID: 32320651

  4. Dibley, M. G.*, Formosa, L. E.*, Lyu, B., Reljic, B., Mcgann, D., Muellner-Wong, L., Kraus, F., Sharpe, A. J., Stroud, D. A. & Ryan, M. T. (2020) The Mitochondrial Acyl-carrier Protein Interaction Network Highlights Important Roles for LYRM Family Members in Complex I and Mitoribosome Assembly. Molecular & cellular proteomics, 19, 65-77. *Co-first author PMID: 31666358

  5. Alston, C. L.*, Compton, A. G.*, Formosa, L. E.*, Strecker, V., Oláhová, M., Haack, T. B., Smet, J., Stouffs, K., Diakumis, P., Ciara, E., Cassiman, D., Romain, N., Yarham, J. W., He, L., De Paepe, B., Vanlander, A. V., Seneca, S., Feichtinger, R. G. G., Płoski, R., Rokicki, D., Pronicka, E., Haller, R. G., Van Hove, J. L., Bahlo, M., Mayr, J. A., Van Coster, R., Prokisch, H., Wittig, I., Ryan, M. T., Thorburn, D. R. & Taylor, R. W. (2016) Biallelic Mutations in TMEM126B Cause Severe Complex I Deficiency with a Variable Clinical Phenotype. American Journal of Human Genetics, 99, 217-227.  *Co-first author PMID: 27374774

  6. Stroud, D. A., Surgenor, E. E., Formosa, L. E., Reljic, B., Frazier, A. E., Dibley, M. G., Osellame, L. D., Stait, T., Beilharz, T. H., Thorburn, D. R., Salim, A. & Ryan, M. T. 2016. Accessory subunits are integral for assembly and function of human mitochondrial complex I. Nature, 538, 123-126. PMID: 27626371

  7. Fernández-Vizarra, E., López-Calcerrada, S., Sierra-Magro, A., Pérez-Pérez, R., Formosa, L. E., Hock, D. H., Illescas, M., Peñas, A., Brischigliaro, M., Ding, S., Fearnley, I. M., Tzoulis, C., Pitceathly, R. D. S., Arenas, J., Martín, M. A., Stroud, D. A., Zeviani, M., Ryan, M. T. & Ugalde, C. (2022) Two independent respiratory chains adapt OXPHOS performance to glycolytic switch. Cell Metabolism. PMID: 36198313

  8. Jackson, T. D., Crameri, J. J., Muellner-Wong, L., Frazier, A. E., Palmer, C. S., Formosa, L. E., Hock, D. H., Fujihara, K. M., Stait, T., Sharpe, A. J., Thorburn, D. R., Ryan, M. T., Stroud, D. A. & Stojanovski, D. (2022) Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module. Proc Natl Acad Sci USA, 119, e2115566119. PMID: 35333655

Additional publications

A full list of Formosa Group publications can be viewed on PubMed.