Law Laboratory
Fibrinolysis and Wound Healing
Fibrinolysis and Wound Healing
We're part of the Monash Biomedicine Discovery Institute, and a member of Cardiovascular Disease and
Immunity Programs and the Department of Biochemistry and Molecular Biology.
My global research connections, partners and funding can be viewed on my Monash Research Profile.
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Our research focus is on characterising the mechanism of plasminogen activation/inhibition in infections (including Clostridium difficile infection and necrotising fasciitis), traumatic injuries, clotting disorders, ischemia and cancer metastasis. Using different approaches such as structural biology, cell biology, biochemistry and monoclonal antibodies, we seek to understanding the role of plasminogen in disease development and wound healing. Our works extend also to areas of therapeutic developments.
1. Understanding the how Streptococcus pyogenes hijacks plasminogen for tissue invasion.
2. Structural studies on plasminogen activators and inhibitors and their utility in diseases management.
3. Binding of plasminogen to cell surface receptors - structure, function and biological consequences.
We are committed to excellence in research.
We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.