Law lab publications

Selected highlight publications

1. Awad MM, Hutton ML, Quek AJ, Klare WP, Mileto SJ, Mackin K, Ly D, Oorschot V, Bosnjak M, Jenkin G, Conroy PJ, West N, Fulcher A, Costin A, Day CJ, Jennings MP, Medcalf RL, Sanderson-Smith M, Cordwell SJ, Law RHP*, Whisstock JC, Lyras D (2020) Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface. Gastroenterology 159 (4) 1431-1443.e6 (joint senior).

2. Spicer BA, Law RHP*, Caradoc-Davies TT, Ekkel SM, Bayly-Jones C, Pang SS, Conroy PJ, Ramm G, Radjainia M, Venugopal H, Whisstock JC, Dunstone MA. The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun. 2018 Aug 15;9(1):3266 (joint first).

3. Law RHP, Caradoc-Davies TT, Cowieson N, Horvath AJ, Quek AJ, Encarnacao JA, Steer D, Cowan A, Zhang Q, Lu BGC, Pike RN, Smith AI, Coughlin PB, Whisstock JC (2012) The X-ray Crystal Structure of Full-Length Human Plasminogen. Cell Reports 1(3):185-190.

4. Law RHP, Lukoyanova N, Voskoboinik I, Caradoc-Davies TT, Baran K, Dunstone MA, D’Angelo ME, Orlova EV, Coulibaly F, Verschoor S, Browne KA, Ciccone A, Kuiper MJ, Bird PI, Trapani JA, Sailil HR, Whisstock JC (2010) The Structural basis for membrane binding and pore formation by lymphocyte perforin. Nature 468(7322):447-51

5. Law RHP, Sofian T, Kan WT, Horvath AJ, Hitchen CR, Langendorf CG, Buckle AM, Whisstock JC, Coughlin PB (2008) The X-ray crystal structure of the fibrinolysis inhibitor 2-antiplasmin Blood 111(4):2049-52.

6. Rosado CJ, Buckle AM, Law RHP*, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL,Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC (2007) A common fold mediates vertebrate defense and bacterial attack Science 317(5844):1548-51 (joint first author).

7. Fenalti G, Law RHP*, Buckle AM, Langendorf C, Tuck K, Rosado CJ, Faux NG, Mahmood K, Hampe CS, Banga JP, Wilce M, Schmidberger J, Rossjohn J, El-Kabbani O, Pike RN, Smith AI, Mackay IR, Rowley MJ, Whisstock JC (2007) GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop Nature Structural and Molecular Biology 14(4):280-6 (joint first author).

Additional publications

A full list of Law Lab publications can be viewed on PubMed & Google Scholar.