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Rosenbluh Laboratory

Cancer Functional Genomics

Welcome to the Rosenbluh Lab

We use state of the art functional genomic tools that include pooled CRISPR and ORF loss/gain of function screens and apply these technologies towards understanding and targeting of cancer.

We're part of the Monash Biomedicine Discovery Institute, and a member of the Cancer Program
and the Department of Biochemistry and Molecular Biology.

Associate Professor Joseph (Sefi) Rosenbluh

My global research connections, partners and funding can be viewed on my Monash Research Profile.

Click the links below to connect with me on ORCID and Google Scholar.

Our research

Genetic screens provide global information about how genes are regulated in normal homeostasis and how they are deregulated in disease. Recent technological advances are revolutionising our ability to use these approaches. Research in our lab uses state of the art functional genomic tools that include pooled CRISPR and ORF loss/gain of function screens and apply these technologies towards understanding and developing new approaches to treat cancer.

We aim to:

  • identify breast cancer risk genes that could be used for development of anti-cancer therapies and as biomarkers to identity women with high risk of developing breast cancer
  • identify new drug targets for gastric cancer therapy
  • target SRP19 in APC deleted colon cancers (and, more generally, targeting any tumour suppressor that is lost in cancer).

Lab members

We are committed to excellence in research.

Publications

View our chosen highlighted key publications.

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News

We want to share our research discoveries & successes with you.

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Join Our Lab

We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.

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