Ryan lab publications

Selected highlight publications

1. Mitochondrial COA7 is a heme-binding protein with disulfide reductase activity, which acts in the early stages of complex IV assembly. Formosa LE, Maghool S, Sharpe AJ, Reljic B, Muellner-Wong L, Stroud DA, Ryan MT, Maher MJ. PNAS. 2022 119 (9):e2110357119

2. Optic atrophy-associated TMEM126A is an assembly factor for the ND4-module of mitochondrial complex I. Formosa LE, Reljic B, Sharpe AJ, Hock DH, Muellner-Wong L, Stroud DA, Ryan MT. PNAS. 2021 118(17):e2019665118

3. Function and regulation of the divisome for mitochondrial fission. Kraus F, Roy K, Pucadyil TJ, Ryan MT. Nature. 2021 590(7844):57-66

4. Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I. Formosa LE, Muellner-Wong L, Reljic B, Sharpe AJ, Jackson TD, Beilharz TH, Stojanovski D, Lazarou M, Stroud DA, Ryan MT. Cell Rep. 2020 31(3):107541

5. The Mitochondrial Acyl-carrier Protein Interaction Network Highlights Important Roles for LYRM Family Members in Complex I and Mitoribosome Assembly. Dibley MG, Formosa LE, Lyu B, Reljic B, McGann D, Muellner-Wong L, Kraus F, Sharpe AJ, Stroud DA, Ryan MT. Mol Cell Proteomics. 2020 19(1):65-77

6. Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission. Kamerkar SC, Kraus F, Sharpe AJ, Pucadyil TJ, Ryan MT. Nat Commun. 2018 9(1):5239

7. Mitochondrial OXPHOS complex assembly lines. Formosa LE, Ryan MT. Nat Cell Biol. 2018 20(5):511-513

8. BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis. McArthur K, Whitehead LW, Heddleston JM, Li L, Padman BS, Oorschot V, Geoghegan ND, Chappaz S, Davidson S, San Chin H, Lane RM, Dramicanin M, Saunders TL, Sugiana C, Lessene R, Osellame LD, Chew TL, Dewson G, Lazarou M, Ramm G, Lessene G, Ryan MT, Rogers KL, van Delft MF, Kile BT. Science. 2018 Feb 23. doi: 10.1126/science.aao6047

9. Accessory subunits are integral for assembly and function of human mitochondrial complex I. Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG,  Osellame LD,  Stait T, Beilharz TH,  Thorburn DR, Salim A, Ryan MT. Nature. 2016 538, 123-126

10. Cooperative and independent roles of Drp1 adaptors Mff and MiD49/51 in mitochondrial fission. Osellame LD, Singh AP, Stroud DA, Palmer CS, Stojanovski D, Ramachandran R, Ryan MT. J Cell Sci. 2016 Apr 12. pii: jcs.185165

Additional publications

A full list of Ryan Lab publications can be viewed on PubMed.