Shahine Group publications
Selected highlight publications
- Huang S*, Shahine A*, Cheng TY, Chen YL, Ng SW, Balaji GR, Farquhar R, Gras S, Hardman CS, Altman JD, Tahiri N, Minnaard AJ, Ogg GS, Mayfield JA, Rossjohn J, Moody DB. CD1 lipidomes reveal lipid-binding motifs and size-based antigen- display mechanisms. Cell. 2023 Oct 12;186(21):4583-4596.e13. doi: 10.1016/j.cell.2023.08.022.
- Lameris R*, Shahine A*, Pellicci DG, Uldrich AP, Gras S, Le Nours J, Groen RWJ, Vree J, Reddiex SJJ, Quiñones-Parra SM, Richardson SK, Howell AR, Zweegman S, Godfrey DI, de Gruijl TD, Rossjohn J, van der Vliet HJ. A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response. Nat Cancer. 2020 Nov;1(11):1054-1065. doi: 10.1038/s43018-020-00111-6.
- Farquhar R, Van Rhijn I, Moody DB, Rossjohn J, Shahine A. αβ T-cell receptor recognition of self- phosphatidylinositol presented by CD1b. J Biol Chem. 2023 Feb;299(2):102849.
doi: 10.1016/j.jbc.2022.102849. - Shahine A, Reinink P, Reijneveld JF, Gras S, Holzheimer M, Cheng TY, Minnaard AJ, Altman JD, Lenz S, Prandi J, Kubler-Kielb J, Moody DB, Rossjohn J, Van Rhijn I. A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nat Commun. 2019 Jan 4;10(1):56. doi: 10.1038/s41467-018-07898-0.
- Shahine A, Van Rhijn I, Cheng TY, Iwany S, Gras S, Moody DB, Rossjohn J. A molecular basis of human T cell receptor autoreactivity toward self- phospholipids. Sci Immunol. 2017 Oct 20;2(16):eaao1384. doi: 10.1126/sciimmunol.aao1384.
Additional publications
A full list of Shahinie Group publications can be viewed here.