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Ellisdon Laboratory

Structural Biology of Signalling
and Cancer

Welcome to the Ellisdon Lab

Our laboratory’s research vision is to determine structures of critical multi-component protein complexes in cancer, TSC and inflammation.

We're part of the Monash Biomedicine Discovery Institute, and a member of the Cancer and Immunity Programs, and the Department of Biochemistry and Molecular Biology.

Dr Andrew Ellisdon

My global research connections, partners and funding can be viewed on my Monash Research Profile.

If you are a student interested in doing research in our lab, visit Supervisor Connect.

Click the links below to connect with me on Twitter, ORCID, Google Scholar and LinkedIn.

Our research

Capturing an atomic view of ‘signalling in action’ is central to the development of targeted therapeutics. Our research vision is to determine structures of critical multi-component protein complexes in cancer and inflammation. This resolution is enabled by combining the latest advances in single-particle cryoEM and crystallography with advanced single-cell fluorescence techniques. The laboratory has a long-term aim to translate modified cytokines to the clinic through current research agreements with major pharmaceutical and biotechnology companies.

  • 1. Translating IL-1 family cytokines to the clinic

  • 2. Molecular mechanism of the Tuberous Sclerosis Complex (TSC); a master-switch of cell growth

  • 3. Structural regulation of GEF and GAP complexes in cancer signalling

Lab members

We are committed to excellence in research.


View our chosen highlighted key publications.

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We want to share our research discoveries & successes with you.

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Join Our Lab

We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.

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