About us
The Australian Translational Medicinal Chemistry Facility (ATMCF) is a national drug discovery facility that helps transform promising biological research into potential new medicines. We partner with researchers, medical research institutes, clinicians, biotechnology companies and translation organisations to advance therapeutic programs from early discovery through to preclinical development.
Our purpose
To accelerate the translation of scientific discoveries into new medicines by providing nationally accessible medicinal chemistry expertise and collaborative drug discovery capability.
What We Do
Our team provides expert medicinal chemistry leadership across all stages of small-molecule drug discovery, including hit identification and validation, lead optimisation, structure-based drug design, computational modelling, and development of intellectual property strategies. By combining scientific expertise with a strong focus on translation, we help researchers overcome the challenges of turning innovative discoveries into commercially and clinically relevant therapeutic opportunities.
ATMCF works across a broad range of disease areas, including cancer, cardiovascular disease, neurological disorders, infectious diseases, inflammatory conditions and rare diseases. Through collaborative project delivery, we support the design of higher-quality drug candidates with improved potency, selectivity, safety and drug-like properties.
As part of Australia's therapeutic innovation ecosystem, ATMCF bridges the gap between fundamental research and real-world health outcomes. Our goal is to accelerate the development of novel Australian therapeutics by providing the medicinal chemistry expertise, strategic guidance and translational capabilities needed to move discoveries closer to patients.