Publications
Publications resulting from work done in the Monash Ramaciotti Centre for Cryo Electron Microscopy
2026
Cyntia Taveneau, Her Xiang Chai, Jovita D'Silva, Rebecca S. Bamert, Honglin Chen, Brooke K. Hayes, Roland W. Calvert, Jacob Purcell, Daniel J. Curwen, Fabian Munder, Lisandra L. Martin, Jeremy J. Barr, Joseph Rosenbluh, Mohamed Fareh, Rhys Grinter, Gavin J. Knott (2026) De novo design of potent CRISPR-Cas13 inhibitors. Nature Chemical Biology https://doi.org/10.1038/s41589-025-02136-3
Rex F. Anane, Anni Kumari, Hari Venugopal, Sylvain Trépout, James C. Whisstock, Lars H. Engelholm, Ruby H.P. Law, Michael Ploug (2026) Structural basis for uPAR binding to an antibody developed for targeted cancer therapy. Mechanistic insights into flexibility, ligand recognition, and molecular imaging. Protein Science https://doi.org/10.1002/pro.70473
Sabrina Suhani, Yan Li, Laura Perlaza-Jiménez, Denis Korneev, Cara Press, Tze Y. Thung, Han-Chung Lee, Joshua J. Iszatt, Ralf B. Schittenhelm, Christopher J Stubenrauch, Rhys A. Dunstan, Joshua M. Hardy, Anthony Kicic, Trevor Lithgow (2026) Staphylococcus species infected by a bacteriophage with a tail that is both curved and contractile. mBio https://doi.org/10.1128/mbio.03829-25
Parisa Eslami, Kevin Hutomo Putera, andrew J. Clulow, Simon Crawford, Gareth H. McKinley, Victoria S. Haritos, Leonie van't Hag (2026) Reinforcement of pea protein isolate gels through NaCl-assisted pea protein fibril formation at acidic pH. Food Hydrocolloids https://doi.org/10.1016/j.foodhyd.2025.112374
Alice Y.J. Tiong, Smitri Shrestha, Edward Attenborough, Paul Michalski, Simon Crawford, Warren Batchelor, Leonie van't Hag (2026) The effect of legume protein source, solubility, pH, and salt addition on the texture of meat analogues. LWT - Food Science and Technology https://doi.org/10.1016/j.lwt.2025.118956
Christopher J. Lupton, Charles Bayly-Jones, Shuqi Dong, Terrance Lam, Wentong Luo, Gareth D. Jones, Chantel Mastos, Nicholas J. Frescher, San S. Lim, Alastair C. Keen, Luke E. Formosa, Hari Venugopal, Yong-Gang Chang, Michelle L. Halls, Andrew M. Ellisdon (2026) Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex. Cell https://doi.org/10.1016/j.cell.2025.12.005
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Haikun Liu, Mark Louis P. Vidallon, Yuyang Song, Aidan P.G. Walsh, Henry Gordon, Shulei Ren, Pengkai Shi, Bangyan Xu, Mitchell J Moon, Sylvain Trépout, Rico F. Tabor, Alexis I. Bishop, Ulrich Flögel, Karlheinz Peter, Xiaowei Wang (2025) Precision mRNA delivery via ultrasound-controlled release perflourocarbon emulsions: An inovative ultrasound theranostic sttrategy with 19F MRI feasibility. Small https://doi.org/10.1002/smll.202506806
Susanne H. D. Ständer, Cyril F. Reboul, Sarah N. Le, Daniel E. Williams, Peter G. Chandler, Mauricio G. S. Costa, David E. Hoke, John D. T. Jimma, James Fodor, Gustavo Fenalti, Stuart I. Mannering, Benjamin T. Poerbski, Daniel Christ, Malcolm Buckle, Sheena McGowan, Dominika Elmlund, Kasper D. Rand, Ashley M. Buckle (2025) Structure and dynamics of GAD65 in complex with an autoimmune polyendocrine syndrome type 2-associated autoantibody. Nature Communications https://doi.org/10.1038/s41467-025-57492-4
Alice Y.J. Tiong, Simon Crawford, Liliana de Campo, Vasyl Ryukhtin, Christopher J. Garvey, Warren Batchelor, Leonie van 't Hag (2025) Legume protein gelation: the mechanism behind the formation of homogenous and fractal gels. Food Hydrocolloids https://doi.org/10.1016/j.foodhyd.2024.110639
Lein N H Dofash, Lee B Miles, Yoshihiko Saito, Eloy Rivas, Vanessa Calcinotto, Sara Oveissi, Rita J Serrano, Rachel Templin, Georg Ramm, Alison Rodger, Joel Haywood, Evan Ingley, Joshua S Clayton, Rhonda L Taylor, Chiara L Folland, David Groth, Daniella H Hock, David A Stroud, Svetlana Gorokhova, Sandra Donkervoort, Carsten G Bönnemann, Malika Sud, Grace E VanNoy, Brian E Mangilog, Lynn Pais, Anne O'Donnell-Luria, Marcos Madruga-Garrido, Marcello Scala, Chiara Fiorillo, Serena Baratto, Monica Traverso, Edoardo Malfatti, Claudio Bruno, Federico Zara, Carmen Paradas, Katsuhisa Ogata, Ichizo Nishino, Nigel G Laing, Robert J Bryson-Richardson, Macarena Cabrera-Serrano, Gianina Ravenscroft (2025) HMGCS1 variants cause rigid spine syndrome amenable to mevalonic acid treatment in an animal model. Brain https://doi.org/10.1093/brain/awae371
Diulia Quites Rodrigues, Mahdi Ghorbani, Jhonatan Soto Puelles, Simon Crawford, Maria Paulis, Maria Forsyth, Anthony E. Somers (2025) Corrosion protection of mild steel in acidic environments by cetrimonium cinnamates in solution and added to a low volatile organic compound coating. ACS Omega https://doi.org/10.1021/acsomega.4c07098
Fabian Munder, Marcos Voutsinos, Klaus Hantke, Hari Venugopal, Rhys Grinter (2025) High-affinity PQQ import is widespread in Gram-negative bacteria. Science Advances https://doi.org/10.1126/sciadv.adr2753
Yunxin Xiao, Alexander W. Jackson, Angel Tan, John F. Quinn, Simon Crawford, Ben J. Boyd (2025) Asymmetric nanocapsules via elongated liposome templated polymerization (ELTP) mediated by RAFT polymerization. Drug Delivery and Translational Research https://doi.org/10.1007/s13346-025-01805-z
Cuong Viet Pham, Haikun Liu, Joshu P. King, Shulei Ren, Sylvain Trépout, Alexis I. Bishop, Rico F. Tabor, Karlheinz Peter, Liliana de Campo, Mark Louis P. Vidallon, Xiaowei Wang (2025) Unlocking the architecture and component distribution of bioengineered and derived colloidal structures from blood with neutron scattering. Small Structures https://doi.org/10.1002/sstr.202500369
Sergey Gorelick, Sailakshmi Velamoor, Patrick Cleeve, Sylvain Trépout, Ying Le, Vivek Naranbhai, Georg Ramm (2025) Mind the corner: Fillets in cryo-FIB lamella preparation to minimise sample loss caused by stress concentration and lamella breakage. Journal of Structural Biology https://doi.org/10.1016/j.jsb.2025.108249
Bill Ho, Charles Bayly-Jones, Corinna Lau, Tom Mollnes, Bradley Spicer, Michelle Dunstone (2025) Structural insights into how the membrane attack complex is recognised by the diagnostic antibody aE11. Immunobiology https://doi.org/10.1016/j.imbio.2025.152987
Bill Ho, Suzanne Wang, Charles Bayly-Jones, Bradley Spicer, Michelle Dunstone (2025) From volume imaging to biological insight: characterizing habenular mitochondria in post-embryonic zebrafish using correlative synchrotron-µCT/FIB-SEM. Immunobiology https://doi.org/10.1016/j.imbio.2025.152945
Joshua M. Hardy, Bronte A. Johnson, Jungmin Ha, Anamarija Butkovic, Paulina Koszalka, Cathy Accurso, Hariprasad Venugopal, Alex de Marco, Mart Krupovic, Fasseli Coulibaly (2025) Determining the architecture of the baculovirus nucleocapsid using sub-tomogram averaging and helical reconstruction. APMC13 Congress/ScienceOpen.com https://doi.org/10.14293/APMC13-2025-0222
Denis Korneev, Rachel Templin, Sergey Gorelick, Minyu Chan, Georg Ramm (2025) Synchrotron-based micro-CT for precise targeting the areas of interest for biological FIB-SEM. APMC13 Congress/ScienceOpen.com https://doi.org/10.14293/APMC13-2025-0219
Liudi Zhang, Jesse I. Mobbs, Felix M. Bennetts, Hariprasad Venugopal, Anh T.N. Nguyen, Arthur Christopoulos, Daan van der Es, Laura H. Heitman, Lauren T. May, Alisa Glukhova, David M. Thal (2025) Molecular basis of ligand binding and recptor activation at the human A3 adenosine receptor. Nature Communications https://doi.org/10.1038/s41467-025-62872-x
Marlena Mucha, Zhihao Lai, Nicholas J. McKenzie, Francesca Matrá, Marion Boudes, Sarena F. Flanigan, Maria Teresa Alejo-Vinogradova, Craig Monger, Qi Zhang, Darragh Nimmo, Evan Healy, Ademar J. Silva, Daniel Angelov, David M. Reck, Gráinne Holland, Zeynep Eda Atmaca, Helen E. King, Maeve Hamilton, Eleanot Glancy, James Nolan, Robert J. Weatheritt, Oliver Bell, Michiel Vermeulen, Chen Davidovich, Adrian P. Bracken (2025) Auto-inhibition of PCR2 by the broadly expressed long isoform of AEBP2. The EMBO Journal https://doi.org/10.1038/s44318-025-00616-9
Maddison L. Graffeo, Joseph Nguyen, Farin Yazdan Parast, Jessica E.M. Dunleavy, Denis Korneev, Hongyi Yang, Hidenobu Okuda, Anne E. Connor, Donald F. Conrad, Reza Nosrati, Brendan J. Houston, Moira K. O'Bryan (2025) A novel mechanism of sperm midpiece epididymal maturation and the role of CCDC112 in sperm midpiece formation and establishing an optimal flagella waveform. Cell Communication and Signalling https://doi.org/10.1186/s12964-025-02320-x
Michelle D. Farrelly, Denis Korneev, Lisandra L. Martin, San H. Thang (2025) Tethering efficiency of reversible addition-fragmentation chain transfer-synthesized styrene maleic acid polymers and associated styrene maleic acid lipid nanoparticles on gold surfaces. ChemPlusChem https://doi.org/10.1002/cplu.202500173
Dinesh Subedi, Fernando Gordillo Altamirano, Rylee Deehan, Avindya Perera, Ruzeen Patwa, Xenia Kostoulias, Denis Korneev, Luke Blakeway, Nenad Macesic, Anton Y Peleg, Jeremy J Barr (2025) Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections. Nature Microbiology https://doi.org/10.1038/s41564-025-02130-4
Wessel A.C. Burger, Jesse I. Mobbs, Bhavika Rana, Jinan Wang, Keya Joshi, Patrick R. Gentry, Mahmuda Yeasmin, Hariprasad Venugopal, Aaron M. Bender, Craig W. Lindsley, Yinglong Miao, Arthur Christopolous, Celine Valant, David M. Thal (2025) Cryo-EM reveals an extrahelical allosteric binding site at the M5mAChR. Nature Communications https://doi.org/10.1038/s41467-025-62212-z
Liam Rashleigh, Hariprasad Venugopal, Michael T. Rice, Sachith D. Gunasinghe, Chhon Ling Sok, Nicholas A. Gherardin, Catarina F. Almeida, Ildiko Van Rhijn, D. Branch Moody, Dale I. Godfrey, Jamie Rossjohn, Benjamin S. Gully (2025) Antibody-like recognition of a γδ T cell receptor toward a foreign antigen. Structure https://doi.org/10.1016/j.str.2025.07.006
Afif Jati, Yan Li, Tze Y. Thung, Huanchang Chen, Joel Steele, Han Lee, Ralf Schittenhelm, Tieli Zhou, Francesca L. Short, Rys A. Dunstan, Trevor Lithgow (2025) Highly stable bacteriophages PIN1 and PIN2 have hallmarks of flagellotropic phages but infect immotile bacteria. npj Viruses https://doi.org/10.1038/s44298-025-00139-4
Daniel R. Fox, Kazem Asadollahi, Imogen Samuels, Bradley A. Spicer, Ashleigh Kropp, Christopher J. Lupton, Kevin Lim, Chunxiao Wang, Hari Venugopal, Marija Dramicanin, Gavin J. Knott, Rhys Grinter (2025) Inhibiting heme piracy by pathogenic Escherichia coli using de novo-designed proteins. Nature Communications https://doi.org/10.1038/s41467-025-60612-9
Andrea F. Wise, IGAA Ari Krisnadevi, Shoni Bruell, Han-Chung Lee, Tejasvini Bhuvan, Andrew J. Kassianos, Sheetal Saini, Xiangju Wang, Helen G. Healy, Elizabeth Ling Qian, David A. Elliot, Joel R Steele, Maria Fuller, Kathleen M. Nicholls, Sharon D. Ricardo (2025) Fabry disease podocytes reveal ferroptosis as a potential regulator of cell pathology. Kidney International Reports https://doi.org/10.1016/j.ekir.2024.11.024
Winnie Tan, Jeongveen Park, Hariprasad Venugopal, Jieqiong Lou, Prabavi Shayana Dias, Pedro L. Baldoni, Kyoung-Wook Moon, Toby A. Dite, Christine R. Keenan, Alexandra D. Gurzau, Joonyoung Lee, Timothy M. Johanson, Andrew Leis, Jumana Yousef, Vineet Vaibhav, Laura F. Dagley, Ching-Seng Ang, Laura D. Corso, Chen Davidovich, Stephin J. Vervoort, Gordon K. Smyth, Marnie E. Blewitt, Rhys S. Allan, Elizabeth Hinde, Sheena D'Arcy, Je-Kyung Ryu, Shabih Shakeel (2025) MORC2 is a phosphorylation-dependent DNA compaction machine. Nature Communications https://doi.org/10.1038/s41467-025-60751-z
Paul Michalski, Shahruk Nur-A-Tomal, Simon Crawford, Murray Rudman, Leonie van ‘t Hag (2025) Advancement in fruit drying through the analysis of moisture sorption isotherms: Processing effects on Australian native fruits in comparison to apple. Journal of Food Engineering https://doi.org/10.1016/j.jfoodeng.2025.112526
Parisa Eslami, Victoria Haritos, Simon Crawford, Leonie van 't Hag (2025) Enhancing rheological and textural properties of pea protein-collagen gels via transglutaminase crosslinking. Food Structure https://doi.org/10.1016/j.foostr.2025.100409
Caitlyn R, Ryan, Andrea F. Wise, Elisha Tindoy,Shoni Bruell, Maria Fuller, Kathleen M. Nicholls, Sharon D. Ricardo (2025) Investigating lysosomal dysfunction in Fabry disease using induced pluripotent stem cell-derived podocytes. Journal of Translational Genetics and Genomics https://doi.org/10.20517/jtgg.2024.87
Sally M. Byers, Andrea Rocker, To N.T. Nguyen, Natalia C. Rosas, George Taiaroa, Kher Shing Tan, Yan Li, Jonathan J. Wilksch, Joel R. Steele, Ralf B. Schittenhelm, Rhys A. Duncan, Francesca L. Short, Trevor Lithgow (2025) Telomere bacteriophages are widespread and equip their bacterial hosts with potent interbacterial weapons. Science Advances https//doi.org/10.1126/sciadv.adt1627
Boqun Liu, Arthur Christopolous, David M. Thal, Ben Capuano, Celine Valant, Peter J. Scammels (2025) The prosperity and adversity of M4 muscarinic acetylcholine receptor activators in the treatment of neuropsychiatric disorders. Journal of Medicinal Chemistry https://doi.org/10.1021/acs.jmedchem.5c00678
Simon T. Bond, Emily J. King, Shannen M. Walker, Christine Yang, Yingying Liu, Kevn H. Liu, Aowen Zhuang, Haoyun A. Fang, Luke E. Formosa, Artika P. Nath, Sergio Ruiz Carmona, Michael Inouye, Thy Duong, Kevin Huynh, Peter J. Meikle, Simon Crawford, Georg Ramm, Sheik Nadeem Elahee Doomun, David P. de Souza, Danielle L. Rudler, Anna C. Calkin, Aleksandra Filipovska, David W. Greening, Darren C. Henstridge & Brian G. Drew (2025) Mitochondrial damage in muscle specific PolG mutant mice activates the integrated stress response and disrupts the mitochondrial folate cycle. Nature Communications https://doi.org/10.1038/s41467-025-57299-3
Bronte A. Johnstone, Joshua M. Hardy, Jungmin Ha, Anamaria Butkovic, Paulina Koszalka, Cathy Accurso, Hariprasad Venugopal, Alex de Marco, Mart Krupovic, Fasséli Coulibaly (2025) The nucleocapsid architecture and structural atlas of the prototype baculovirus define the hallmarks of a new viral realm. Science Advances 10 (51) https://doi.org/10.1126/sciadv.ado2631
Michael Ucklemann, Vita Levina, Cyntia Taveneau, Xiao Han Ng, Varun Pandey, Jasmine Martinez, Shweta Mendiratta, Justin Houx, Marion Boudes, Hari Venugopal, Sylvain Trépout, Alex J. Fulcher, Qi Zhang, Sarena Flanigan, Minrui Li, Emma Sierecki, Yann Gambin, Partha Pratim Das, Oliver Bell, Alex de Marco, Chen Davidovich (2025) Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates. Nature Structural & Molecular Biology https://doi.org/10.1038/s41594-024-01457-6
Anwai Archit, Luca Freeman, Sushmita Nair, Nabeel Khalid, Paul Hilt, Vikas Rajashekar,Marei Feitag, Carolin Teuber, Genevieve Buckley, Sebastian von Haaren, Sagnik Gupta, Andreas Dengal, Sheraz Ahmed, Constantin Pape (2025) Segment Anything for Microscopy. Nature Methods https://doi.org/10.1038/s41592-024-02580-4
Ashleigh Kropp, David L. Gillett, Hari Venugopal, Miguel A. Gonzalvez, James P. Lingford, Christopher K. Barlow, Jie Zhang, Chris Greening, Rhys Grinter (2025) Quinone extraction drives atmospheric carbon monoxide oxidation in bacteria. Nature Chemical Biology https://doi.org/10.1038/s41589-025-01836-0
Hariprasad Venugopal, Jesse Mobbs, Cyntia Taveneau, Daniel R. Fox, Ziva Vuckovic, Sahil Gulati, Gavin Knott, Rhys Grinter, David Thal, Stephen Mick, Cory Czarnik, Georg Ramm (2025) High-resolution cryo-EM using a common LaB6 120-keV electron microscope equipped with a sub-200-keV direct electron detector. Science Advances 11(1) https://doi.org/10.1126/sciadv.adr0438
Julien Clegg, Rodrigo Curvello, Anastasiia Gabrielyan, Daniel Croagh, Sandra Hauser, Daniela Loessner (2025) Tailoring metabolic activity assays for tumour-engineered 3D models. Biomaterials Advances 167: 214116 https://doi.org/10.1016/j.bioadv.2024.214116
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Xiangfeng Lai, Lei Yu, Xiangyi Huang, Wil Gardner, Sarah E. Bamford, Paul J. Pigram, Shuhong Wang, Anton P. Le Brun, Benjamin W. Muir, Jiangning Song, Yajun Wang, Hsien-Yi Hsu, Philip Wai Hong Chan, Hsin-Hui Shen (2024) Enhanced nitric oxide delivery through self-assembling nanoparticles for eradicating gram-negative bacteria. Advanced Healthcare Materials https://doi.org/10.1002/adhm.202403046
Shengrong Du, Tony Huynh, Yen-Zhen Lu, Bradyn J. Parker, Stephen K. Tham, Helmut Thissen, Mikael M. Martino, Neil R. Cameron (2024) Bioactive polymer composite scaffolds fabricated from 3D printed negative molds enable bone formation and vascularization. Acta Biomaterialia https://doi.org/10.1016/j.actbio.2024.07.038
Shun-ichi Yamashita, Ritsuko Arai, Hiroshi Hada, Benjamin Scott Padman, Michael Lazarou, David C. Chan, Tomotake Kanki, Satoshi Waguri (2024) The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondria. Journal of Cell Biology https://doi.org/10.1083/jcb.202408166
Iain J. Abbott, Connor R.B. Anderson, Elke van Gorp, Steve C. Wallis, Jason A. Roberts, Joseph Meletiadis, Anton Y. Peleg (2024) Oral ciprofloxacin biofilm activity in a catheter-associated urinary tract infection model. Journal of Antimicrobial Chemotherapy https://doi.org/10.1093/jac/dkae424
Hari Venugopal, Ashleigh Kropp, Chris Greening, Rhys Grinter (2024) Determining the high-resolution structure of the [NiFE]-hydrogenase Huc by native host purification and cryo-EM. Cryo-Electron Microscopy in Structural Biology https://doi.org/10.1201/9781003326106-17
Aude Dorison, Ines Paz Santos, Irene Ghobrial, Rachel Lam, Katrin Stuber, Jillian Clare Danne, Micheal M. See, Georg Ramm, Fernando Jaime Rossello, Mirana Ramialison, Kristina B. Emdal, Melissa H. Little (2024) Endosomal recycling and proteasomal degradation of R168H variant podocin contributes to nephrotic syndrome pathophysiology. Journal of the American Society of Nephrology https://doi.org/10.1681/ASN.20243by4g38b
Lein NH Dofash, Lee B Miles, Yoshihiko Saito, Eloy Rivas, Vanessa Calcinotto, Sara Oveissi, Rita J Serrano, Rachel Templin, Georg Ramm, Alison Rodger, Joel Haywood, Evan Ingley, Joshua S Clayton, Rhonda L Taylor, Chiara L Folland, David Groth, Daniella H Hock, David A Stroud, Svetlana Gorokhova, Sandra Donkervoort, Carsten G Bönnemann, Malika Sud, Grace VanNoy, BrianE Mangilog, Lynn Pais, Marcos Madruga-Garrido, Marcello Scala, Chiara Fiorillo, Serena Baratto, Monica Traverso, Claudio Bruno, Federico Zara, Carmen Paradas, Katsuhisa Ogata, Ichizo Nishino, Nigel G Laing, Robert J Bryson-Richardson, Macarena Cabrera-Serrano, Gianina Ravenscroft (2024) Biallelic variants in HMGCS1 are a novel cause of rare rigid spine syndrome. Brain https://doi.org/10.1093/brain/awae371
Tze Y. Thung, Alex Hall, Afif P. Jati, Murray E. White, Rebecca S. Bamert, Kher Shing Tan, Cara Press, George Taiaroa, Francesca L. Short, Rhys A. Dunstan, Trevor Lithgow (2024) Genetic variation in individuals from a population of the minimalist bacteriophage Merri-merri-uth nyilam marra-natj driving evolution of the virus. mBio https://doi.org/10.1128/mbio.02564-24
Kaleeckal G.Harikumar, Peishen Zhao, Brian P. Cary, Xiaomeng Xu, Aditya J. Desai, Maoqing Dong, Jesse I. Mobbs, Chirine Toufaily, Sebastian G. B. Furness, Arthur Christopoulos, Matthew J. Belousoff, Denise Wootten, Patrick M. Sexton, Laurence J. Miller (2024) Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling. PLOS Biology https://doi.org/10.1371/journal.pbio.3002673
Maytham Hussein, Zhisen Kang, Stephanie L. Neville, Rafah Allobawi, Varsha Thrombare, Augustine Jing Jie Koh, Jonathan Wilksch, Simon Crawford, Mudher Khudhur Mohammed, Christopher A. McDevitt, Mark Baker, Gauri G. Rao, Jian Li, Tony Velkov (2024) Metabolic profiling unveils enhanced antibacterial synergy of polymyxin B and teixobactin against multi-drug resistant Acinetobacter baumannii. Scientific Reports https://doi.org/10.1038/s41598-024-78769-6
Tom Dierschke, Jonathan Levins, Edwin R. Lampugnani, Berit Ebert, Sabine Zachgo, John L. Bowman (2024) Control of sporophyte secondary cell wall development in Marchantia by a Class II KNOX gene. Current Biology https://doi.org/10.1016/j.cub.2024.09.061
Charles Bayly-Jones, Christopher J. Lupton, Laura D'Andrea, Yong-Gang Chang, Gareth D. Jones, Joel R. Steele, Hari Venugopal, Ralf B. Schittenhelm, Michelle Halls, Andrew Ellisdon (2024) Structure of the human TSC:WIPI3 lysosomal recruitment complex. Science Advances https://doi.org/10.1126/sciadv.adr5807
Haikun Liu, Mark Louis P. Vidallon, Sylvain Trepout, Mitchell J. Moon, Marina Cagnes, Nageshwar Rao Yepuri, Rico F. Tabor, Karlheinz Peter, Liliana de Campo, Xiaowei Wang (2024) Neutron scattering strategies for investigating internal architecture of mRNA lipid nanoparticle. Proceedings of the World Congress on New Technologies https://doi.org/10.11159/icnfa24.103
Mark Louis P. Vidallon, Mitchell J. Moon, Haikun Liu, Yuyang Song, Simon Crawford, Boon Mian Teo, James D. McFadyen, Alexis J. Bishop, Rico F. Tabor, Karlheinz Peter, Xiaowei Wang (2024) Engineering hyperechogenic colloids with clot-targeting capabilities from platelet-derived membranes. ACS Applied Materials and Interfaces https://doi.org/10.1021/acsami.4c12024
Sylvain Trepout, Marie-Laure Sgarra, Sergio Marco, Georg Ramm (2024) An introduction to scanning transmission electron microscopy for the study of protozoans. Molecular Microbiology https://doi.org/10.1111/mmi.15213
Alice Y.J. Tiong, Simon Crawford, Nykola C. Jones, Gareth H. McKinley, Warren Batchelor, Leonie van ’t Hag (2024) Pea and soy protein isolate fractal gels: The role of protein composition, structure and solubility on their gelation behaviour. Food Structure https://doi.org/10.1016/j.foostr.2024.100374
Subhash Dhital, Pankaj Deo, Isabella Stuart, Cheng Huang, Lauren Zavan, Mei-Ling Han, Maria Kaparakis-Liaskos, Georg Ramm, Ralf B. Schittenhelm, Benjamin Howden, Thomas Naderer (2024) Characterization of outer membrane vesicles released by clinical isolates of Neisseria gonorrhoeae. Proteomics https://doi.org/10.1002/pmic.202300087
Jarmon G. Lees, David W. Greening, David A. Rudd, Jonathon Cross, Ayeshah A. Rosdah, Xiangfeng Lai, Tsung Wu Lin, Ren Jie Phang, Anne M. Kong, Yali Deng, Simon Crawford, Jessica K. Holien, Derek J. Hausenlon, Hsin-Hui Shen, Shiang Y. Lim (2024) Cardiac-targeted delivery of a novel Drp1 inhibitor for acute cardioprotection. Journal of Molecular and Cellular Cardiology Plus https://doi.org/10.1016/j.jmccpl.2024.100085
Brooke K. Hayes, Marina Harper, Hariprasad Venugopal, Jessica Lewis, Amy Wright, Han-Chung Lee, Joel R. Steele, David L. Steer, Ralf B. Schittenhelm, John D. Boyce, Sheena McGowan (2024) Structure of a Rhs effector clade domain provides mechanistic insights into type IV secretion system toxin delivery. Nature Communications https://doi.org/10.1038/s41467-024-52950-x
Alice Y.J. Tiong, Simon Crawford, Liliana de Campo, Vasyl Ryukhtin, Christopher J. Garvey, Warren Batchelor, Leonie van't Hag (2024) Legume protein gelation: The mechanism behind the formation of homogenous and fractal gels. Food Hydrocolloids https://doi.org/10.1016/j.foodhyd.2024.110639
Charles Bayly-Jones, Christopher J. Lupton, Alastair C. Keen, Shuqi Dong, Chantel Mastos, Wentong Luo, Chunyi Qian, Gareth D. Jones, Hari Venugopal, Yong-Gang Chang, Ronald J. Clarke, Michelle Halls, Andrew Ellisdon (2024) LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR. Nature https://doi.org/10.1038/s41586-024-08012-9
Elizabeth Reisman, Javier Botella Ruiz, Cheng Huang, Ralf B Schittenhelm, David Arthur Stroud, Cesare Granata, Shavin Chandrasiri, Georg Ramm, Viola Oorschot, Nikeisha J Caruana, David J Bishop (2024) Fibre-specific mitochondrail protein abundance is linked to resting and post-training mitochondrial content in human muscle. Nature Communications 15:7677 https://doi.org/10.1038/s41467-024-50632-2
Mark Louis P. Vidallon, Ashley P. Williams, Mitchell J. Moon, Haikun Liu, Sylvain Trepout, Alexis I. Bishop, Boon Mian Teo, Rico F. Tabor, Karlheinz Peter, Liliana de Campo, Xiaowei Wang (2024) Revealing the structural intricacies of Biomembrane-interfaced emulsions with small- and ultra-small-angle neutron scattering. Small Methods https://doi.org/10.1002/smtd.202400348
Benjamin S. Gully, Joao Ferreira Fernandes, Sachith D. Gunasinghe, Mai T. Vuong, Michael T. Rice, Liam Rashleigh, Chan-sien Lay, Dene R. Littler, Sumana Sharma, Ana Mafalda Santos, Hariprasad Venugopal, Jamie Rossjohn, Simon J. Davis (2024) Structure of a fully assembled γδ T-cell antigen receptor. Nature https://doi.org/10.1038/s41586-024-07920-0
Karly C. Sourris, Yi Ding, Scott S. Maxwell, Anna Al-sharea, Phillip Kantharidis, Muthukumar Mohan, Carlos J. Rosado, Sally A. Penfold, Claus Haase, Yangsong Xu, Josephine M. Forbes, Simon Crawford, Georg Ramm, Brooke E. Harcourt, Karin Jandeleit-Dahm, Andrew Advani, Andrew J. Murphy, Daniel B Timmermann, Anil Karihaloo, Lotte Bjerre Knudsen, Asam El-Osta, Daniel J. Druker, Mark E. Cooper, Melinda T. Coughlan (2024) Glucagon-like peptide-1 receptor signalling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products-induced inflammation. Kidney International 105 (1): 132-147 https://doi.org/10.1016/j.kint.2023.09.029
Benjamin Kroeger, Samuel A. Manning, Yoshana Fonseka, Viola Oorschot, Simon A. Crawford, Georg Ramm, Kieran F. Harvey (2024) Basal spot junctions of Drosophilia epithelial tissues respond to morphogenetic forces and regulate Hippo signalling. Developmental Cell 59 (2): 262-279 https://doi.org/10.1016/j.devcel.2023.11.024
Dinesh Subedi, Fernando Gordillo Altamirano, Rylee Deehan, Avindya Perera, Ruzeen Patwa, Xenia Kostoulias, Denis Korneev, Luke Blakeway, Nenad Macesic, Anton Y Peleg, Jeremy J Barr (2024) Rational design of frontline institutional phage cocktail for the treatment of nosocomial Enterobacter cloacae complex infections. BioRxiv https://doi.org/10.1101/2024.06.30.601436
Zhao Qing Tang, Felipe Basquiroto de Souza, Kwesi Sagoe-Crentsil, Wenhui Duan (2024) Enhancing geopolymer performance with silane-functionalized graphene oxide: Efflorescence reduction, pore refinement, and improved high-temperature properties. Construction and Building Materials 440: 137420 https://doi.org/10.1016/j.conbuildmat.2024.137420
Brendan J Houston, D Jo Merriner, G Gemma Stathatos, Joseph H Nguyen, Anne E O’Connor, Alexandra M Lopes, Donald F Conrad, Mark Baker, Jessica EM Dunleavy, Moira K O’Bryan (2024) Genetic mutation of Cep76 results in male infertility due to abnormal sperm tail composition. Life Science Alliance 7 (6) https://doi.org/10.26508/lsa.202302452
Susanne H. D. Ständer, Cyril F. Reboul, Sarah N. Le, Daniel E. Williams, Peter G. Chandler, Mauricio G. S. Costa, David E. Hoke, John D. T. Jimma, James Fodor, Gustavo Fenalti, Stuart I. Mannering, Benjamin T. Porebski, Peter Schofield, Daniel Christ, Malcolm Buckle, Sheena McGowan, Dominika Elmlund, Kasper D. Rand, Ashley M. Buckle (2024) Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11. BioRxiv https://doi.org/10.1101/2024.03.18.585568
Felix M. Bennets, Hariprasad Venugopal, Alisa Glukhova, Jesse I. Mobbs, Sabatino Ventura, David M. Thal (2024) Structural insights into the human P2X1 receptor and ligand interactions. Nature Communications 15:8418 https://doi.org/10.1038/s41467-024-52776-7
Robson K. Loterio, Ebony A. Monson, Rachel Templin, Jyotika T. de Bruyne, Heather A. Flores, Jason M. Mackenzie, Georg Ramm, Karla J. Helbig, Cameron P. Simmons, Johanna E. Fraser (2024) Anitviral Wolbachia strains associate with Aedes aegypti endoplasmic reticulum membranes and induce lipid droplet formation to restrict dengue virus replication. mBio 15: e02495-23 https://doi.org/10.1128/mbio.02495-23
Fabian Munder, Marcos Voutsinos, Klaus Hantke, Hari Venugopal, Rhys Grinter (2024) High-affinity PQQ import is widespread in Gram-negative bacteria. BioRxiv https://doi.org/10.1101/2024.06.04.597491
Sue C. Nang, Jing Lu, Heidi H. Yu, Hasini Wickremasinghe, Mohammad A.K. Azad, Meiling Han, Jinxin Zhao, Gauri Rao, Phillip J. Bergen, Tony Velkov, Norelle Sherry, David T. McCarthy, Saima Aslam, Robert T. Schooley, Benjamin P. Howden, Jeremy J. Barr, Yan Zhu, Jian Li (2024) Phage resistance in Klebsiella pneumoniae and bidirectional effects impacting antibiotic susceptibility. Clinical Microbiology and Infection 30 (6): 787-794 https://doi.org/10.1016/j.cmi.2024.03.015
Xiangfeng Lai, Seong Hoong Chow, Anton P. Le Brun, Benjamin W. Muir, Phillip J. Bergen, Jacinta White, Heidi H. Yu, Jiping Wang, Jill Danne, Jhih-hang Jiang, Francesca L. Short, Mei-Ling Han, Richard A. Strugnell, Jiangning Song, Neil R. Cameron, Anton Y. Peleg, Jian Li, Hsin-Hui Shen (2024) Polysaccaride-targeting lipd nanoparticles to kill gram-negative bacteria. Small 20: 2305052 https://doi.org/10.1002/smll.202305052
Hariprasad Venugopal, Jesse Mobbs, Cyntia Taveneau, Daniel R. Fox, Ziva Vuckovic, Gavin Knott, Rhys Grinter, David Thal, Stephen Mick, Cory Czarnik, Georg Ramm (2024) Obtaining high-resolution cryo-EM structures using a common LaB6, 120eV electron microscope equipped with a sub 200-keV optimised direct electron detector. bioRxiv https://doi.org/10.1101/2024.05.26.595910
Muthu Vignesh Vellayappan, Francisco Duarte, Cyrille Sollogoub, Justin Dirrenberger, Alain Guinault, Jessica E. Frith, Helena C. Parkington, Andrey Molotnikov, Neil R. Cameron (2024) Creation of grooved tissue engineering scaffolds from architectured multilayer polymer composites by a tunable one-step degradation process. Small https://doi.org/10.1002/smll.202401902
Jianjun Cao, Matthew J. Belousoff, Radostin Danev, Arthur Christopoulos, Denise Wootten, Patrick M. Sexton (2024) Cryo-EM structure of the Human Amylin 1 receptor in complex with CGRP and Gs protein. Biochemistry 63(9): 1089-1096 https://doi.org/10.1021/acs.biochem.4c00114
Isabella C. Russell, Xin Zhang, Fabian Bumbak, Samantha M. McNeill, Tracy M. Josephs, Michael J, Leeming, George Christopoulos, Hariprasad Venugopal, Maria M. Flocco, Patrick M. Sexton, Denise Wootten, Matthew J. Belousoff (2024) Lipid-dependent activation of the orphan G protein-coupled receptor, GPR3. Biochemistry 63 (5): 625-631 https://doi.org/10.1021/acs.biochem.3c00647
G Gemma Stathatos, D Jo Merriner, Anne E O'Connor, Jennifer Zenker, Jessica EM Dunleavy, Moira K O'Bryan (2024) Epsilon tubulin is an essential determinanat of microtubule-based structures in male germ cells. EMBO Reports 25: 2711-2742 https://doi.org/10.1038/s44319-024-00159-w
Genevieve Buckley, Georg Ramm, Sylvain Trepout (2024) GoldDigger and Checkers, computational developments in cryo-scanning transmission electron tomography to improve the quality of reconstructed volumes. Biological Imaging 4:e6 https://doi.org/10.1017/S2633903X24000047
Emily A McKaige, Clara Lee, Vanessa Calcinotto, Saveen Giri, Simon Crawford, Meagan J McGrath, Georg Ramm, Robert J Bryson-Richardson (2024) Mitochondrial abnormalities contribute to muscle weakness in a Dnajb6 deficient zebrafish model. Human Molecular Genetics https://doi.org/10.1093/hmg/ddae061
Tahnee L. Saunders, Simon P. Windley, Gediminas Gervinskas, Katherine R. Balka, Caitlin Rowe, Rachael Lane, Maximilien Tailler, Thanh Ngoc Nguyen, Georg Ramm, Michael Lazarou, Dominic De Nardo, Benjamin T. Kile & Kate McArthur (2024) Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy. Cell Death and Differentiation https://doi.org/10.1038/s41418-024-01260-2
Jonathan Levins, Tom Dierschke, John L. Bowman (2024) A subclass II bHLH transcription factor inMarchantia polymorphagives insight into the ancestral land plant trait of spore formation. Current Biology 34: 1-7 https://doi.org/10.1016/j.cub.2024.01.008
Christian K. O. Dzuvor, Hsin-Hui Shen, Victoria S. Haritos, Lizhong He (2024) Coassembled Multicomponent Protein Nanoparticles Elicit Enhanced Antibacterial Activity. ACS Nano 18 (5): 4478-4494 https://doi.org/10.1021/acsnano.3c11179
Ashleigh Kropp, David L. Gillett, Hari Venugopal, Miguel A. Gonzalvez, James P. Lingford, Christopher K. Barlow, Jie Zhang, Chris Greening, Rhys Grinter (2024) Quinone extraction drives atmospheric carbon monoxide oxidation in bacteria. BioRxiv https://doi.org/10.1101/2024.01.09.574806
Mark Louis P. Vidallon, Joshua P. King, Luke W. Giles, Simon A. Crawford, Chris Baldwin, Dino Premilovac, Boon Mian Teo, Alexis I. Bishop, Liliana de Campo, Rico F. Tabor (2024) Studying the photothermal activation of polydopamine-shelled, phase-change emulsion droplets into microbubbles using small- and ultra-small-angle neutron scattering. Journal of Colloid and Interface Science 659: 1029-1041 https://doi.org/10.1016/j.jcis.2024.01.004
Martina Chrudinova, Nicholas S. Kirk, Aurelian Chuard, Hari Venugopal, Fa Zhang, Marta Lubos, Vasily Gelfanov, Terezie Panikova, Lenka Zakova, Julianne Cutone, Matthew Mojares, Richard DiMarchi, Jiri Jiracek, Emrah Altindis (2024) A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression. Molecular Metabolism 80: 101863 https://doi.org/10.1016/j.molmet.2023.101863
Urvashi Bothra, Hariprasad Venugopal, Dinash Kabra, Christopher R. McNeill, Amelia C.Y. Liu (2024) Visualization of Nanocrystallites in Organic Semiconducting Blends Using Cryo-Electron Microscopy. Small Methods https://doi.org/10.1002/smtd.202301352
Cameron M. Kewish, Sergey Gorelick, David M. Paganin, Martin D. de Jonge (2024) Optimum design of aspect ratio limited x-ray zone plates. Optica 11 (2): 251-262. https://doi.org/10.1364/OPTICA.505082
Jillian C Danne, Rachel Templin, Gediminas Gervinskas, Denis Korneev, Sergey Gorelick, Georg Ramm (2024) Preparation of Cells for Volume Electron Microscopy using Focused Ion Beam Scanning Electron Microscopy (FIB-SEM). protocols.io https://dx.doi.org/10.17504/protocols.io.n92ldmeq7l5b/v1
-
Charles Nunez, Xenia Kostoulias, Anton Y Peleg, Francesca Short, Yue Qu (2023) A comprehensive comparison of biofilm formation and capsule production for bacterial survival on hospital surfaces. Biofilm 5. 100105 https://doi.org/10.1016/j.bioflm.2023.100105
Ziva Vuckovic, Jinan Wang, Vi Pham, Jesse I Mobbs, Matthew J Belousoff, Apurba Bhattarai, Wessel AC Burger, Geoff Thompson, Mahmuda Yeasmin, Vindhya Nawaratne, Katie Leach, Emma T van der Westhuizen, Elham Khajehali, Yi-Lynn Liang, Alisa Glukhova, Denise Wootten, Craig W Lindsley, Andrew Tobin, Patrick Sexton, Radostin Danev, Celine Valant, Yinglong Miao, Arthur Christopoulos, David M Thal (2023) Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics. Elife 12, e83477 https://doi.org/10.7554/eLife.83477
Thanh Ngoc Nguyen, Justyna Sawa-Makarska, Grace Khuu, Wai Kit Lam, Elias Adriaenssens, Dorotea Fracchiolla, Stephen Shoebridge, Daniel Bernklau, Benjamin Scott Padman, Marvin Skulsuppaisarn, Runa SJ Lindblom, Sascha Martens, Michael Lazarou (2023) Unconventional initiation of PINK1/Parkin mitophagy by optineurin. Molecular Cell 83 (10) 1693 https://doi.org/10.1016/j.molcel.2023.04.021
Zhao Qing Tang, Hao Sui, Felipe Basquiroto de Souza, Kwesi Sagoe-Crentsil, Wenhui Duan (2023) Silane-modified graphene oxide in geopolymer: Reaction kinetics, microstructure, and mechanical performance. Cement and Concrete Composites 139, 104997 https://doi.org/10.1016/j.cemconcomp.2023.104997
Christian KO Dzuvor, Bhuvana K Shanbhag, Hsin‐Hui Shen, Victoria S Haritos, Lizhong He (2023) An Ultra‐stable Self‐assembled Antibacterial Nanospears made of Protein. Advanced Materials 2302409 https://doi.org/10.1002/adma.202302409
Muthu Vignesh Vellayappan, Francisco Duarte, Cyrille Sollogoub, Justin Dirrenberger, Alain Guinault, Jessica E Frith, Helena C Parkington, Andrey Molotnikov, Neil R Cameron (2023) Fabrication of Architectured Biomaterials by Multilayer Co‐Extrusion and Additive Manufacturing. Advanced Functional Materials 2301547 https://doi.org/10.1002/adfm.202301547
Rhys Grinter, Ashleigh Kropp, Hari Venugopal, Moritz Senger, Jack Badley, Princess R Cabotaje, Ruyu Jia, Zehui Duan, Ping Huang, Sven T Stripp, Christopher K Barlow, Matthew Belousoff, Hannah S Shafaat, Gregory M Cook, Ralf B Schittenhelm, Kylie A Vincent, Syma Khalid, Gustav Berggren, Chris Greening (2023) Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature 615 (752) 541 https://doi.org/10.1038/s41586-023-05781-7
Samuel R Cheers, Anne E O'Connor, Travis K Johnson, D Jo Merriner, Moira K O'Bryan, Jessica EM Dunleavy (2023) Spastin is an essential regulator of male meiosis, acrosome formation, manchette structure and nuclear integrity. Development 150 (6) dev201183 https://doi.org/10.1242/dev.201183
Qianqian Shi, Dashen Dong, Gediminas Gervinskas, Han Lin, Debabrata Sikdar, Baohua Jia, Sumeet Walia, Sharath Sriram, Madhu Bhaskaran, Lim Wei Yap, Wenlong Cheng (2023) Soft Plasmene Helical Nanostructures. Advanced Materials Technologies 2201866 https://doi.org/10.1002/admt.202201866
Charles Bayly-Jones, Bill HT Ho, Corinna Lau, Eleanor WW Leung, Laura D’Andrea, Christopher J Lupton, Susan M Ekkel, Hariprasad Venugopal, James C Whisstock, Tom E Mollnes, Bradley A Spicer, Michelle A Dunstone (2023) The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9. Communications Biology 6 (1) 42 https://doi.org/10.1038/s42003-023-04431-y
Sining Ye, Paschalis Theotokis, Jae Young Lee, Min Joung Kim, Danica Nheu, Olivia Ellen, Thomas Bedford, Padmanabhan Ramanujam, David K Wright, Stuart J McDonald, Amani Alrehaili, Maha Bakhuraysah, Jung Hee Kang, Christopher Siatskas, Cedric S Tremblay, David J Curtis, Nikolaos Grigoriadis, Mastura Monif, Stephen M Strittmatter, Steven Petratos (2023) Nogo receptor-Fc delivered by haematopoietic cells enhances neurorepair in a multiple sclerosis model. Brain Communications 5 (2) fcad108 https://doi.org/10.1093/braincomms/fcad108
Michael Uckelmann, Vita Levina, Cyntia Taveneau, Xiao Han Ng, Varun Pandey, Qi Zhang, Sarena Flanigan, Minrui Li, Partha Pratim Das, Alex de Marco, Chen Davidovich (2023) Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates. bioRxivhttps://doi.org/10.1101/2023.05.08.539931
Meg L McFetridge, Ketav Kulkarni, Volker Hilsenstein, Mark P Del Borgo, Marie-Isabel Aguilar, Sharon D Ricardo (2023) A comparison of fixation methods for SEM analysis of self-assembling peptide hydrogel nanoarchitecture. Nanoscale 15, 1431 https://doi.org/10.1039/D2NR04598B
Brian P Cary, Elliot J Gerrard, Matthew J Belousoff, Madeleine M Fletcher, Yan Jiang, Isabella C Russell, Sarah J Piper, Denise Wootten, Patrick M Sexton (2023) Molecular insights into peptide agonist engagement with the PTH receptor. Structure 31 (6) 668 https://doi.org/10.1016/j.str.2023.04.002
Eugene M Obeng, David L Steer, Alex J Fulcher, Kylie M Wagstaff (2023) Sortase A transpeptidation produces seamless, unbranched biotinylated nanobodies for multivalent and multifunctional applications. Nanoscale Advances 5 (8) 2251 https://doi.org/10.1039/D3NA00014A
I Banakh, Md M Rahman, CL Arellano, DC Marks, S Mukherjee, CE Gargett, H Cleland, S Akbarzadeh (2023) Platelet lysate can support the development of a 3D-engineered skin for clinical application. Cell and Tissue Research 391 (1) 173 https://doi.org/10.1007/s00441-022-03698-7
Jesse I Mobbs, Katrina A Black, Michelle Tran, Hariprasad Venugopal, Theodore R Holman, Michael Holinstat, David M Thal, Alisa Glukhova (2023) Cryo-EM structures of human arachidonate 12S-Lipoxygenase (12-LOX) bound to endogenous and exogenous inhibitors. bioRxiv https://doi.org/10.1101/2023.03.10.532002
Jillian C Danne, Viola Oorschot, Georg Ramm (2023) Tokuyasu processing and immuno-electron microscopy of tissue. Protocols.io https://dx.doi.org/10.17504/protocols.io.5jyl8jj9dg2w/v1
G. Gemma Stathatos, D. Jo Merriner, Anne E. O’Connor, Jennifer Zenker, Jessica E.M. Dunleavy, Moira K. O’Bryan (2023) Epsilon tubulin is an essential determinant of microtubule-based structures in male germ cells. bioRxiv https://doi.org/10.1101/2023.06.07.544006
Gemma L. D’Adamo, Michelle Chonwerawong, Linden J. Gearing, Vanessa R. Marcelino, Jodee A. Gould, Emily L. Rutten, Sean M. Solari, Patricia W.R. Khoo, Trevor J. Wilson, Tamblyn Thomason, Emily L. Gulliver, Paul J. Hertzog, Edward M. Giles, Samuel C. Forster (2023) Bacterial clade-specific analysis identifies distinct epithelial responses in inflammatory bowel disease. Cell Reports Medicine 4 (7) 101124 https://doi.org/10.1016/j.xcrm.2023.101124
J. A. Pollock, L. C. P. Croton, K. S. Morgan, K. J. Crossley, M. J. Wallace, G. A. Buckley, S. B. Hooper, M. J. Kitchen (2023) Robust propagation-based phase retrieval for CT in proximity to highly attenuating objects. arXiv>Physics>Medical Physics https://doi.org/10.48550/arXiv.2301.12647
Zhao Qing Tang, Felipe Basquiroto de Souza , Johnathan Kapelles , Akil Habibullah, Kwesi Sagoe-Crentsil and Wenhui Duan (2023) Performance evaluation and production of stronger, more durable and sustainable geopolymer incorporating sand washing waste. SSRN (preprint) http://dx.doi.org/10.2139/ssrn.4501165
Crystal Cooper, R.C. Andrew Thompson, Peta Clode (2023) Investigating parasites in three dimensions: trends in volume microscopy. Trends in Parasitology 38 (8) 668-681 https://doi.org/10.1016/j.pt.2023.05.004
Brendan J. Houston, D. Jo Merriner, G. Gemma Stathatos, Anne E. O’Connor, Alexandra M. Lopes, Donald F. Conrad, Mark Baker, Jessica E.M. Dunleavy, Moira K. O’Bryan (2023) CEP76 is a critical regulator of male germ cell transition zone function and tail composition. bioRxiv https://doi.org/10.1101/2023.03.08.531794
Karen Privat, Lisa Yen, Rhiannon Kuchel (2023) The Microscopy Australia staff shadowing scheme: Peer-to-peer knowledge exchange building a connected microscopy community. Microscopy and Microanalysis 29 (supp 1): 2056-2057 https://doi.org/10.1093/micmic/ozad067.1064
ZheHao Tan, Pam Hall, Adam Costin, Simon A. Crawford, Georg Ramm, Connie H. Y. Wong, A. Richard Kitching, Michael J. Hickey (2023) Removal of the endothelial surface layer via hyaluronidase does not modulate monocyte and neutrophil interactions with the glomerular endothelium. Microcirculation e12823 https://doi.org/10.1111/micc.12823
Sue C. Nang, Jing Lu, Heidi H. Yu, Hasini Wickremasinghe, Mohammad A. K. Azad, Meiling Han, Jinxin Zhao, Gauri Rao, Phillip J. Bergen, Tony Velkov, Norelle L. Sherry, David T. McCarthy, Saima Aslam, Robert T. Schooley, Benjamin Howden, Jeremy Barr, Yan Zhu, Li, Jian (2023) Diversified Repertoire of Phage Defenses in Klebsiella pneumoniae: Bi-Directional Steering Effects Impacting Antibiotic Susceptibility. Available at SSRN: https://ssrn.com/abstract=4541700 or http://dx.doi.org/10.2139/ssrn.4541700
Vikram Singh Raghuwanshi, David Joram Mendoza, Christine Browne, Meri Ayurini, Gediminas Gervinskas, Joel F. Hooper, Jitendra Mata, Chun-Ming Wu, George P. Simon, Gil Garnier (2023) Effect of temperature on the conformation and functionality of poly(N-isopropylacrylamide) (PNIPAM)-grafted nanocellulose hydrogels. Journal of Colloid and Interface Science 652 (B): 1609-1619 https://doi.org/10.1016/j.jcis.2023.08.152
Jonathan Levins, Tom Dierschke, John Bowman (2023) The roles of a subclass II bHLH transcription factor in Marchantia polyforma give insights into the ancestral function of spore formation in land plants. Available at SSRN: https://ssrn.com/abstract=4571089 or http://dx.doi.org/10.2139/ssrn.4571089
Robson K. Loterio, Ebony A. Monson, Rachel Templin, Jyotika T. Bruyne, Heather A. Flores, Jason M. Mackenzie, Georg Ramm, Karla J. Helbig, Cameron P. Simmons, Johanna E. Fraser (2023) Antiviral Wolbachia strains associate with Aedes aegypti endoplasmic reticulum membranes and disturb host cell lipid distribution to restrict dengue virus replication. bioRxiv https://doi.org/10.1101/2023.09.14.557745
Wessel AC Burger, Vi Pham, Ziva Vuckovic, Alexander S. Powers, Jesse I Mobbs, Yianni Laloudakis, Alisa Glukhova, Denise Wootten, Andrew B Tobin, Patrick M Sexton, Steven M. Paul, Christian C Felder, Radostin Danev, Ron O Dror, Arthur Christopoulos, Celine Valant, David M Thal (2023) Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR. Nature Communications 14: 5440 https://doi.org/10.1038/s41467-023-41199-5
Malinda Salim, Alastair K.H. MacGibbon, Cameron J. Nowell, Andrew J. Clulow, Ben J. Boyd (2023) Influence of Casein and Milk Phospholipid Emulsifiers on the Digestion and Self-Assembled Structures of Milk Lipids. Colloids and Interfaces 7: 3 https://doi.org/10.3390/colloids7030056
Jianjun Cao, Matthew J. Belousoff, Elliot Gerrard, Radostin Danev, Madeleine M. Fletcher, Emma Dal Maso, Herman Schreuder, Katrin Lorenz, Andreas Evers, Garima Tiwari, Melissa Besenius, Ziyu Li, Rachel M. Johnson, Denise Wootten, Patrick M. Sexton (2023) Structural insight into selectivity of amylin and calcitonin receptor agonists. Nature Chemical Biology https://doi.org/10.1038/s41589-023-01393-4
Eugene M. Obeng, David L. Steer, Alex Fulcher, Kylie M. Wagstaff (2023) Steric-deficient oligoglycine surrogates facilitate multivalent and bifunctional nanobody synthesis via combined sortase A transpeptidation and click chemistry. Bioconjugate Chemistry 34 (9): 1667-1668 https://doi.org/10.1021/acs.bioconjchem.3c00319
Patrick Cleeve, David Dierickx, Lucile Naegele, Rohit Kannachel, Lachlan Burne, Genevieve Buckley, Sergey Gorelick, James C. Whisstock, Alex de Marco (2023) OpenFIBSEM: A universal API for FIBSEM control. Journal of Structural Biology 215 (3): 107967 https://doi.org/10.1016/j.jsb.2023.107967
Randini Nanayakkara, Rajendra Gurung, Samuel J. Rodgers, Matthew Eramo, Georg Ramm, Christina A. Mitchell, Meagan J. McGrath (2023) Autophagic lysosome reformation in health and disease. Autophagy 19 (5): 1378 – 1395 https://doi.org/10.1080/15548627.2022.2128019
Lein NH Dofash, Lee B Miles, Yoshihiko Saito, Eloy Rivas, Vanessa Calcinotto, Sara Oveissi, Rita J Serrano, Rachel Templin, Georg Ramm, Alison Rodger, Joel Haywood, Evan Ingley, Joshua S Clayton, Rhonda L Taylor, Chiara L Folland, David Groth, Daniella H Hock, David A Stroud, Svetlana Gorokhova, Sandra Donkervoort, Carsten G Bönnemann, Malika Sud, Grace VanNoy, Brian E Mangilog, Lynn Pais, Marcos Madruga Garrido, Marcello Scala, Chiara Fiorillo, Serena Baratto, Monica Traverso, Claudio Bruno, Federico Zara, Carmen Paradas, Katsuhisa Ogata, Ichizo Nishino, Nigel G Laing, Robert J Bryson-Richardson, Macarena Cabrera-Serrano, Gianina Ravenscroft (2023) Biallelic variants in HMGCS1 are a novel cause of rare rigid spine syndrome. MedRxiv https://doi.org/10.1101/2023.10.25.23297129
Sylvain Trepout, Marie-Laure Sgarra, Sergio Marco, Georg Ramm (2023) An introduction to scanning transmission electron microscopy for the study of protozoans. Molecular Microbiology https://doi.org/10.1111/mmi.15213
Subhash Dhital, Pankaj Deo, Isabella Stuart, Cheng Huang, Lauren Zavan, Mei-Ling Han, Maria Kaparakis-Liaskos, Georg Ramm, Ralf B. Schittenhelm, Benjamin Howden, Thomas Naderer (2023) Characterization of outer membrane vesicles released by clinicla isolates of Neisseria gonorrhoeae. Proteomics https://doi.org/10.1002/pmic.202300087
-
Kagan B.J., Kitchen A.C., Tran N.T., Habibollahi F., Khajehnejad M., Parker B.J., Bhat A., Rollo B., Razi A., Friston K.J. (2022) In vitro neurons learn and exhibit sentience when embodied in a simulated game-world. Neuron 110 (23) 3952 https://doi.org/10.1016/j.neuron.2022.09.001
Piper S.J., Deganutti G., Lu J., Zhao P., Liang Y.-L., Lu Y., Fletcher M.M., Hossain M.A., Christopoulos A., Reynolds C.A., Danev R., Sexton P.M., Wootten D. (2022) Understanding VPAC receptor family peptide binding and selectivity. Nature Communications 13 (1) 7013 https://doi.org/10.1038/s41467-022-34629-3
Moreau F., Kirk N.S., Zhang F., Gelfanov V., List E.O., Chrudinová M., Venugopal H., Lawrence M.C., Jimenez V., Bosch F., Kopchick J.J., DiMarchi R.D., Altindis E., Ronald Kahn C. (2022) Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist. Nature Communications 13 (1) 6700 https://doi.org/10.1038/s41467-022-34391-6
Bayly-Jones C., Lupton C.J., Fritz C., Venugopal H., Ramsbeck D., Wermann M., Jäger C., de Marco A., Schilling S., Schlenzig D., Whisstock J.C. (2022) Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor. Nature Communications 13 (1) 6178 https://doi.org/10.1038/s41467-022-33893-7
Kirk N.S., Chen Q., Wu Y.G., Asante A.L., Hu H., Espinosa J.F., Martínez-Olid F., Margetts M.B., Mohammed F.A., Kiselyov V.V., Barrett D.G., Lawrence M.C. (2022) Activation of the human insulin receptor by non-insulin-related peptides. Nature Communications 13 (1) 5695 https://doi.org/10.1038/s41467-022-33315-8
Chen Y., Yoh H.Z., Shokouhi A.-R., Murayama T., Suu K., Morikawa Y., Voelcker N.H., Elnathan R. (2022) Role of actin cytoskeleton in cargo delivery mediated by vertically aligned silicon nanotubes. Journal of Nanobiotechnology 20 (1) 406 https://doi.org/10.1186/s12951-022-01618-z
Deganutti G., Liang Y.-L., Zhang X., Khoshouei M., Clydesdale L., Belousoff M.J., Venugopal H., Truong T.T., Glukhova A., Keller A.N., Gregory K.J., Leach K., Christopoulos A., Danev R., Reynolds C.A., Zhao P., Sexton P.M., Wootten D. (2022) Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation. Nature Communications 13 (1) 92 https://doi.org/10.1038/s41467-021-27760-0
Bothra U., Hui P., Tan W.L., Gann E., Venugopal H., Subramaniam C., Liu A.C.Y., McNeill C.R., Kabra D. (2022) Visualization of sub-nanometer scale multi-orientational ordering in thin films of polymer/non-fullerene acceptor blends. Journal of Materials Chemistry A 10 (46) 24662 https://doi/org/10.1039/d2ta05083h
Lee I.-W., Adhikari D., Carroll J. (2022) Miro1 depletion disrupts spatial distribution of mitochondria and leads to oocyte maturation defects. Frontiers in Cell and Developmental Biology 10, 986454 https://doi.org/10.3389/fcell.2022.986454
Rodgers S.J., Jones E.I., Arumugam S., Hamila S.A., Danne J., Gurung R., Eramo M.J., Nanayakkara R., Ramm G., McGrath M.J., Mitchell C.A. (2022) Endosome maturation links PI3Kα signaling to lysosome repopulation during basal autophagy. EMBO Journal 41 (19) e110398 https://doi.org/10.15252/embj.2021110398
Olivier F.A.B., Hilsenstein V., Weerasinghe H., Weir A., Hughes S., Crawford S., Vince J.E., Hickey M.J., Traven A. (2022) The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways. Cell Reports 40 (12) 111374 https://doi.org/10.1016/j.celrep.2022.111374
Tang Z.Q., de Souza F.B., Mulder R.J., KwesiSagoe-Crentsil, Duan W. (2022) Multistep nucleation and growth mechanism of aluminosilicate gel observed by cryo-electron microscopy. Cement and Concrete Research 159, 106873 https://doi.org/10.1016/j.cemconres.2022.106873
Zhang S., Gervinskas G., Qiu S., Venugopal H., Marceau R.K.W., De Marco A., Li J., Fu J. (2022) Methods of Preparing Nanoscale Vitreous Ice Needles for High-Resolution Cryogenic Characterization. Nano Letters 22 (16) 6501 https://doi.org/0.1021/acs.nanolett.2c01495
Chaudhari A., Brugger J., Ram R., Chowdhury P., Etschmann B., Guagliardo P., Xia F., Pring A., Gervinskas G., Liu A., Frierdich A. (2022) Synchronous solid-state diffusion, dissolution-reprecipitation, and recrystallization leading to isotopic resetting: insights from chalcopyrite replacement by copper sulphides. Geochimica et Cosmochimica Acta 331, 48 https://doi.org/10.1016/j.gca.2022.06.005
Xu Y., Margetts M.B., Venugopal H., Menting J.G., Kirk N.S., Croll T.I., Delaine C., Forbes B.E., Lawrence M.C. (2022) How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor. Structure 30 (8) 767 https://doi.org/10.1016/j.str.2022.05.007
Chang Y.-G., Lupton C.J., Bayly-Jones C., Keen A.C., D’Andrea L., Lucato C.M., Steele J.R., Venugopal H., Schittenhelm R.B., Whisstock J.C., Halls M.L., Ellisdon A.M. (2022) Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism. Nature Structural and Molecular Biology 29 (8) 767 https://doi.org/10.1038/s41594-022-00804-9
West D.L., Loughlin F.E., Rivero-Rodríguez F., Vankadari N., Velázquez-Cruz A., Corrales-Guerrero L., Díaz-Moreno I., Wilce J.A. (2022) Regulation of TIA-1 Condensates: Zn2+ and RGG Motifs Promote Nucleic Acid Driven LLPS and Inhibit Irreversible Aggregation. Frontiers in Molecular Biosciences 9, 960806 https://doi.org/10.3389/fmolb.2022.960806
Chin W.H., Kett C., Cooper O., Museler D., Zhang Y., Bamert R.S., Patwa R., Woods L.C., Devendran C., Korneev D., Tiralongo J., Lithgow T., McDonald M.J., Neild A., Barr J.J. (2022) Bacteriophages evolve enhanced persistence to a mucosal surface. Proceedings of the National Academy of Sciences of the United States of America 119 (27) e2116197119 https://doi.org/10.1073/pnas.2116197119
Berger J., Berger S., Currie P.D. (2022) Mob4-dependent STRIPAK involves the chaperonin TRiC to coordinate myofibril and microtubule network growth. PLoS Genetics 18 (6) e1010287 https://doi.org/10.1371/journal.pgen.1010287
Gordillo Altamirano F.L., Kostoulias X., Subedi D., Korneev D., Peleg A.Y., Barr J.J. (2022) Phage-antibiotic combination is a superior treatment against Acinetobacter baumannii in a preclinical study. eBioMedicine 80,104045 https://doi.org/10.1016/j.ebiom.2022.104045
Vidallon M.L.P., Salimova E., Crawford S.A., Teo B.M., Tabor R.F., Bishop A.I. (2022) Enhanced photoacoustic imaging in tissue-mimicking phantoms using polydopamine-shelled perfluorocarbon emulsion droplets. Ultrasonics Sonochemistry 86, 105041 https://doi.org/10.1016/j.ultsonch.2022.106041
Turner D.L., Templin R.M., Barugahare A.A., Russ B.E., Turner S.J., Ramm G., Mathias R.A. (2022) UL34 Deletion Restricts Human Cytomegalovirus Capsid Formation and Maturation. International Journal of Molecular Sciences 23 (10) 5773 https://doi.org/10.3390/ijms23105773
Cao J., Belousoff M.J., Liang Y.-L., Johnson R.M., Josephs T.M., Fletcher M.M., Christopoulos A., Hay D.L., Danev R., Wootten D., Sexton P.M. (2022) A structural basis for amylin receptor phenotype. Science 375 (6587) eabm9609 https://doi.org/10.1126/science.abm9609
Soto Puelles J., Ghorbani M., Crawford S., Ackland M.L., Chen F., Forsyth M., Somers A.E. (2022) Modelling cetrimonium micelles as 4-OH cinnamate carriers targeting a hydrated iron oxide surface. Journal of Colloid and Interface Science 610, 785 https://doi.org/10.1016/j.jcis.2021.11.139
Ghorbani M., Soto Puelles J., Forsyth M., Zhu H., Crawford S., Chen F., Cáceres-Vélez P.R., Jusuf P.R., Somers A. (2022) Engineering Advanced Environmentally Friendly Corrosion Inhibitors, Their Mechanisms, and Biological Effects in Live Zebrafish Embryos. ACS Sustainable Chemistry and Engineering 10 (9) 2960 https://doi.org/10.1021/acssuschemeng.1c07958
McGregor J., Hardy J.M., Lay C.-S., Boo I., Piontek M., Suckow M., Coulibaly F., Poumbourios P., Center R.J., Drummer H.E. (2022) Virus-Like Particles Containing the E2 Core Domain of Hepatitis C Virus Generate Broadly Neutralizing Antibodies in Guinea Pigs. Journal of Virology 96 (5) e01675-21 https://doi.org/10.1128/jvi.01675-21
Garciaz S., Guirguis A.A., Müller S., Brown F.C., Chan Y.-C., Motazedian A., Rowe C.L., Kuzich J.A., Chan K.L., Tran K., Smith L., Macpherson L., Liddicoat B., Lam E.Y.N., Cañeque T., Burr M.L., Litalien V., Pomilio G., Poplineau M., Duprez E., Dawson S.-J., Ramm G., Cox A.G., Brown K.K., Huang D.C.S., Wei A.H., McArthur K., Rodriguez R., Dawson M.A. (2022) Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death. Cancer Discovery 12 (3) 774 https://doi.org/10.1158/2159-8290.CD-21-0522
Berger J., Berger S., Mok Y.S.G., Li M., Tarakci H., Currie P.D. (2022) Genetic dissection of novel myopathy models reveals a role of CapZα and Leiomodin 3 during myofibril elongation. PLoS Genetics 18 (2) e1010066 https://doi.org/10.1371/journal.pgen.1010066
Hardy J.M., Dunstan R.A., Lithgow T., Coulibaly F. (2022) Tall tails: Cryo-electron microscopy of phage tail DNA ejection conduits. Biochemical Society Transactions 50 (1) 459 https://doi.org/10.1042/BST20210799
Vidallon M.L.P., Giles L.W., Pottage M.J., Butler C.S.G., Crawford S.A., Bishop A.I., Tabor R.F., de Campo L., Teo B.M. (2022) Tracking the heat-triggered phase change of polydopamine-shelled, perfluorocarbon emulsion droplets into microbubbles using neutron scattering. Journal of Colloid and Interface Science 607, 836 https://doi.org/10.1016/j.jcis.2021.08.162
Nanayakkara R., Gurung R., Rodgers S.J., Eramo M.J., Ramm G., Mitchell C.A., McGrath M.J. (2022) Autophagic lysosome reformation in health and disease. Autophagy 19 (5) 1378 https://doi.org/10.1080/15548627.2022.2128019
Dzuvor C.K.O., Shanbhag B.K., Younas T., Shen H.-H., Haritos V.S., He L. (2022) Engineering Self-Assembled Endolysin Nanoparticles against Antibiotic-Resistant Bacteria. ACS Applied Bio Materials 5 (10) 4993 https://doi.org/10.1021/acsabm.2c00741
Algarni A., Pilkington E.H., Suys E.J.A., Al-Wassiti H., Pouton C.W., Truong N.P. (2022) In vivo delivery of plasmid DNA by lipid nanoparticles: the influence of ionizable cationic lipids on organ-selective gene expression. Biomaterials Science 10, 2940 https://doi.org/10.1039/d2bm00168c
Han M.-L., Nang S.C., Lin Y.-W., Zhu Y., Yu H.H., Wickremasinghe H., Barlow C.K., Creek D.J., Crawford S., Rao G., Dai C., Barr J.J., Chan K., Turner Schooley R., Velkov T., Li J. (2022) Comparative metabolomics revealed key pathways associated with the synergistic killing of multidrug-resistant Klebsiella pneumoniae by a bacteriophage-polymyxin combination. Computational and Structural Biotechnology Journal 20, 485 https://doi.org/10.1016/j.csbj.2021.12.039
Shanbhag B.K., Liu C., Pradeep G.C., Younas T., Hu K.K.Y., Fulcher A.J., Struwe W.B., Steer D., Dumsday G., Harper I.S., Kukura P., Haritos V.S., He L. (2022) Custom Design of Protein Particles as Multifunctional Biomaterials. Advanced Functional Materials 32 (2) 2108039 https://doi.org/10.1002/adfm.202108039
Yoh H.Z., Chen Y., Aslanoglou S., Wong S., Trifunovic Z., Crawford S., Lestrell E., Priest C., Alba M., Thissen H., Voelcker N.H., Elnathan R. (2022) Polymeric Nanoneedle Arrays Mediate Stiffness-Independent Intracellular Delivery. Advanced Functional Materials 32 (3) 2104828 https://doi.org/10.1002/adfm.202104828
Jianjun Cao, Matthew Belousoff, Radostin Danev, Madeleine Fletcher, Emma dal Maso, Herman Schreuder, Katrin Lorenz, Andreas Evers, Garima Tiwari, Melissa Besenius, Ziyu Li, Rachel Johnson, Denise Wootten, Patrick M Sexton (2022) Structure-based insight into development of selective and non-selective amylin and calcitonin receptor agonists. Researchsquare.com https://doi.org/10.21203/rs.3.rs-2268316/v1
Randini Nanayakkara, Rajendra Gurung, Samuel J Rodgers, Matthew J Eramo, Georg Ramm, Christina A Mitchell, Meagan J McGrath (2022) Autophagic lysosome reformation in health and disease. Autophagy 19 (5) 1378 https://doi.org/10.1080/15548627.2022.2128019
Kimberly Meechan, Wei Guan, Alfons Riedinger, Vera Stankova, Azumi Yoshimura, Rosa Pipitone, Arthur Milberger, Helmuth Schaar, Inés Romero-Brey, Rachel Templin, Christopher J Peddie, Nicole L Schieber, Martin L Jones, Lucy Collinson, Yannick Schwab (2022) Crosshair, semi-automated targeting for electron microscopy with a motorised ultramicrotome. Elife 11, e80899 https://doi.org/10.7554/eLife.80899
Patrick Cleeve, David Dierickx, Genevieve Buckley, Sergey Gorelick, Lucile Naegele, Lachlan Burne, James C Whisstock, Alex de Marco (2022) OpenFIBSEM: an application programming interface for easy FIB/SEM automation. bioRxiv https://doi.org/10.1101/2022.11.01.514681
Jillian C Danne, Simon A Crawford, Rachel Templin, Joan Clark, Viola Oorschot, Georg Ramm (2022) Preparation of tissue for transmission electron microscopy ultrastructural analysis. Protocols.io https://dx.doi.org/10.17504/protocols.io.n92ldpz9nl5b/v1
Johan Decelle, Ehsan Kayal, Estelle Bigeard, Benoit Gallet, Jeremy Bougoure, Peta Clode, Nicole Schieber, Rachel Templin, Elisabeth Hehenberger, Gerard Prensier, Fabien Chevalier, Yannick Schwab, Laure Guillou (2022) Intracellular development and impact of a marine eukaryotic parasite on its zombified microalgal host. The ISME Journal 16 (10) 2348 https://doi.org/10.1038/s41396-022-01274-z
Maxime Durelle, Sophie Charton, Frédéric Gobeaux, Corinne Chevallard, Luc Belloni, Fabienne Testard, Sylvain Trépout, David Carriere (2022) Coexistence of Transient Liquid Droplets and Amorphous Solid Particles in Nonclassical Crystallization of Cerium Oxalate. The Journal of Physical Chemistry Letters 13 (36) 8502 https://doi.org/10.1021/acs.jpclett.2c01829
Antoine Cossa, Sylvain Trépout (2022) Cryo-electron Microscopy to Analyze the Structure of Bacterial Amyloids In Vitro. Bacterial Amyloids: Methods and Protocols 2538 https://doi.org/10.1007/978-1-0716-2529-3_2
Zhaotong Cong, Yi-Lynn Liang, Qingtong Zhou, Sanaz Darbalaei, Fenghui Zhao, Wenbo Feng, Lihua Zhao, H Eric Xu, Dehua Yang, Ming-Wei Wang (2022) Structural perspective of class B1 GPCR signalling. Trends in Pharmacological Sciences 43 (4) 321 https://doi.org/10.1016/j.tips.2022.01.002
Mei-Ling Han, Sue C Nang, Yu-Wei Lin, Yan Zhu, H Yu Heidi, Hasini Wickremasinghe, Christopher K Barlow, Darren J Creek, Simon Crawford, Gauri Rao, Chongshan Dai, Jeremy J Barr, Kim Chan, Robert Turner Schooley, Tony Velkov, Jian Li (2022) Comparative metabolomics revealed key pathways associated with the synergistic killing of multidrug-resistant Klebsiella pneumoniae by a bacteriophage-polymyxin combination. Computational and Structural Biotechnology Journal 20, 485 https://doi.org/10.1016/j.csbj.2021.12.039
Sue Chin Nang, Jing Lu, Heidi Yu, Hasini Wickremasinghe, Mohammad AK Azad, Meiling Han, Jinxin Zhao, Gauri Rao, Phillip J Bergen, Tony Velkov, Norelle Sherry, David T McCarthy, Saima Aslam, Robert T Schooley, Benjamin P Howden, Jeremy J Barr, Yan Zhu, Jian Li (2022) Diversified repertoire of phage defenses in Klebsiella pneumoniae: Bi-directional steering effects impacting antibiotic susceptibility. bioRxiv https://doi.org/10.1101/2022.11.14.516531
Elizabeth Reisman, Javier Botella Ruiz, Cheng Huang, Ralf B Schittenhelm, David Arthur Stroud, Cesare Granata, Shavin Chandrasiri, Georg Ramm, Viola Oorschot, Nikeisha J Caruana, David J Bishop (2022) Single-fibre proteomics reveals a greater fibre-type specific mitochondrial remodelling with moderate than high-intensity training. bioRxiv https://doi.org/10.1101/2022.10.23.512956
-
Dunleavy J.E.M., O'Connor A.E., Okuda H., Merriner D.J., O'Bryan M.K. (2021) KATNB1 is a master regulator of multiple katanin enzymes in male meiosis and haploid germ cell development. Development (Cambridge, England) 148 (24) https://doi.org/10.1242/dev.199922
Barber B.W., Dumont C., Caisse P., Simon G.P., Boyd B.J. (2021) A 3D-printed polymer–lipid-hybrid tablet towards the development of bespoke SMEDDS formulations. Pharmaceutics 13 (12) 2107 https://doi.org/10.3390/pharmaceutics13122107
Lupton C.J., Bayly-Jones C., D’Andrea L., Huang C., Schittenhelm R.B., Venugopal H., Whisstock J.C., Halls M.L., Ellisdon A.M. (2021) The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1. Nature Structural and Molecular Biology 28 (12) 982 https://doi.org/10.1038/s41594-021-00687-2
Ivanova E.P., Linklater D.P., Aburto-Medina A., Le P., Baulin V.A., Khuong Duy Nguyen H., Curtain R., Hanssen E., Gervinskas G., Hock Ng S., Khanh Truong V., Luque P., Ramm G., Wösten H.A.B., Crawford R.J., Juodkazis S., Maclaughlin S. (2021) Antifungal versus antibacterial defence of insect wings. Journal of Colloid and Interface Science 603, 886 https://doi.org/10.1016/j.jcis.2021.06.093
Hardy J.M., Newton N.D., Modhiran N., Scott C.A.P., Venugopal H., Vet L.J., Young P.R., Hall R.A., Hobson-Peters J., Coulibaly F., Watterson D. (2021) A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses. Nature Communications 12 (1) 3266 https://doi.org/10.1038/s41467-021-22773-1
Rodgers S.J., Ooms L.M., Oorschot V.M.J., Schittenhelm R.B., Nguyen E.V., Hamila S.A., Rynkiewicz N., Gurung R., Eramo M.J., Sriratana A., Fedele C.G., Caramia F., Loi S., Kerr G., Abud H.E., Ramm G., Papa A., Ellisdon A.M., Daly R.J., McLean C.A., Mitchell C.A. (2021) INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer. Nature Communications 12 (1) 3140 https://doi.org/10.1038/s41467-021-23241-6
Cook M., Etschmann B., Ram R., Ignatyev K., Gervinskas G., Conradson S.D., Cumberland S., Wong V.N.L., Brugger J. (2021) The nature of Pu-bearing particles from the Maralinga nuclear testing site, Australia. Scientific Reports 11 (1) 10698 https://doi.org/10.1038/s41598-021-89757-5
Horne C.R., Venugopal H., Panjikar S., Wood D.M., Henrickson A., Brookes E., North R.A., Murphy J.M., Friemann R., Griffin M.D.W., Ramm G., Demeler B., Dobson R.C.J. (2021) Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism. Nature Communications 12 (1) 1988 https://doi.org/10.1038/s41467-021-22253-6
Oorschot V., Lindsey B.W., Kaslin J., Ramm G. (2021) TEM, SEM, and STEM-based immuno-CLEM workflows offer complementary advantages. Scientific Reports 11 (1) 899 https://doi.org/10.1038/s41598-020-79637-9
Zhang S., Garg V., Gervinskas G., Marceau R.K.W., Chen E., Mote R.G., Fu J. (2021) Ion-Induced Bending with Applications for High-Resolution Electron Imaging of Nanometer-Sized Samples. ACS Applied Nano Materials 4 (11) 12745 https://doi.org/10.1021/acsanm.1c03396
Feng G., Tan W., Karuthedath S., Li C., Jiao X., Liu A.C.Y., Venugopal H., Tang Z., Ye L., Laquai F., McNeill C.R., Li W. (2021) Revealing the Side-Chain-Dependent Ordering Transition of Highly Crystalline Double-Cable Conjugated Polymers. Angewandte Chemie - International Edition 60 (48) 25499 https://doi.org/10.1002/anie.202111192
Alves D., Sparrow R., Garnier G. (2021) Rapidly freeze-dried human red blood cells for pre-transfusion alloantibody testing reagents. Journal of Biomedical Materials Research - Part B Applied Biomaterials 109 (11) 1689 https://doi.org/10.1002/jbm.b.34825
Zhang S., Gervinskas G., Liu Y., Marceau R.K.W., Fu J. (2021) Nanoscale coating on tip geometry by cryogenic focused ion beam deposition. Applied Surface Science 564, 150355 https://doi.org/10.1016/j.apsusc.2021.150355
Wheatley A.K., Pymm P., Esterbauer R., Dietrich M.H., Lee W.S., Drew D., Kelly H.G., Chan L.-J., Mordant F.L., Black K.A., Adair A., Tan H.-X., Juno J.A., Wragg K.M., Amarasena T., Lopez E., Selva K.J., Haycroft E.R., Cooney J.P., Venugopal H., Tan L.L., O Neill M.T., Allison C.C., Cromer D., Davenport M.P., Bowen R.A., Chung A.W., Pellegrini M., Liddament M.T., Glukhova A., Subbarao K., Kent S.J., Tham W.-H. (2021) Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Reports 37 (2) 109822 https://doi.org/10.1016/j.celrep.2021.109822
Acter S., Vidallon M.L.P., Crawford S., Tabor R.F., Teo B.M. (2021) Bowl-Shaped Mesoporous Polydopamine Nanoparticles for Size-Dependent Endocytosis into HeLa Cells. ACS Applied Nano Materials 4 (9) 9536 https://doi.org/10.1021/acsanm.1c01897
Draper-Joyce C.J., Bhola R., Wang J., Bhattarai A., Nguyen A.T.N., Cowie-Kent I., O’Sullivan K., Chia L.Y., Venugopal H., Valant C., Thal D.M., Wootten D., Panel N., Carlsson J., Christie M.J., White P.J., Scammells P., May L.T., Sexton P.M., Danev R., Miao Y., Glukhova A., Imlach W.L., Christopoulos A. (2021) Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia. Nature 597 (7877) 571 https://doi.org/10.1038/s41586-021-03897-2
Parker A.M., Tate M., Prakoso D., Deo M., Willis A.M., Nash D.M., Donner D.G., Crawford S., Kiriazis H., Granata C., Coughlan M.T., De Blasio M.J., Ritchie R.H. (2021) Characterisation of the Myocardial Mitochondria Structural and Functional Phenotype in a Murine Model of Diabetic Cardiomyopathy. Frontiers in Physiology 12, 672252 https://doi.org/10.3389/fphys.2021.672252
Grinter R., Morris F.C., Dunstan R.A., Leung P.M., Kropp A., Belousoff M., Gunasinghe S.D., Scott N.E., Beckham S., Peleg A.Y., Greening C., Li J., Heinz E., Lithgow T. (2021) Bona from acinetobacter baumannii forms a divisome-localized decamer that supports outer envelope function. mBio 12 (4) e01480-21 https://doi.org/10.1128/mBio.01480-21
Mobbs J.I., Belousoff M.J., Harikumar K.G., Piper S.J., Xu X., Furness S.G.B., Venugopal H., Christopoulos A., Danev R., Wootten D., Thal D.M., Miller L.J., Sexton P.M. (2021) Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity. PLoS Biology 19 (6) e3001295 https://doi.org/10.1371/journal.pbio.3001295
Thung T.Y., White M.E., Dai W., Wilksch J.J., Bamert R.S., Rocker A., Stubenrauch C.J., Williams D., Huang C., Schittelhelm R., Barr J.J., Jameson E., McGowan S., Zhang Y., Wang J., Dunstan R.A., Lithgow T. (2021) Component parts of bacteriophage virions accurately defined by a machine-learning approach built on evolutionary features. mSystems 6 (3) e00242-21 https://doi.org/10.1128/mSystems.00242-21
Douek A.M., Khabooshan M.A., Henry J., Stamatis S.-A., Kreuder F., Ramm G., Änkö M.-L., Wlodkowic D., Kaslin J. (2021) An engineered sgsh Mutant Zebrafish recapitulates molecular and behavioural pathobiology of sanfilippo syndrome A/MPS IIIA. International Journal of Molecular Sciences 22 (11) 5948 https://doi.org/10.3390/ijms22115948
Jelmakas E., Kadys A., Dmukauskas M., Grinys T., Tomašiūnas R., Dobrovolskas D., Gervinskas G., Juodkazis S., Talaikis M., Niaura G. (2021) FIB micro-milled sapphire for GaN maskless epitaxial lateral overgrowth: a systematic study on patterning geometry. Journal of Materials Science: Materials in Electronics 32 (11) 14532 https://doi.org/10.1007/s10854-021-06010-5
Ghavamian S., Hay I.D., Habibi R., Lithgow T., Cadarso V.J. (2021) Three-Dimensional Micropatterning Deters Early Bacterial Adherence and Can Eliminate Colonization. ACS Applied Materials and Interfaces 13 (20) 23339 https://doi.org/10.1021/acsami.1c01902
Pymm P., Adair A., Chan L.-J., Cooney J.P., Mordant F.L., Allison C.C., Lopez E., Haycroft E.R., O'Neill M.T., Tan L.L., Dietrich M.H., Drew D., Doerflinger M., Dengler M.A., Scott N.E., Wheatley A.K., Gherardin N.A., Venugopal H., Cromer D., Davenport M.P., Pickering R., Godfrey D.I., Purcell D.F.J., Kent S.J., Chung A.W., Subbarao K., Pellegrini M., Glukhova A., Tham W.-H. (2021) Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice. Proceedings of the National Academy of Sciences of the United States of America 118 (19) e2101918118 https://doi.org/10.1073/pnas.2101918118
Payne J.A.E., Kulkarni K., Izore T., Fulcher A.J., Peleg A.Y., Aguilar M.-I., Cryle M.J., Del Borgo M.P. (2021) Staphylococcus aureus entanglement in self-assembling β-peptide nanofibres decorated with vancomycin. Nanoscale Advances 3 (9) 2607 https://doi.org/10.1039/d0na01018a
Nguyen T.N., Padman B.S., Zellner S., Khuu G., Uoselis L., Lam W.K., Skulsuppaisarn M., Lindblom R.S.J., Watts E.M., Behrends C., Lazarou M. (2021) ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system. Molecular Cell 81 (9) 2013 https://doi.org/10.1016/j.molcel.2021.03.001
Newton N.D., Hardy J.M., Modhiran N., Hugo L.E., Amarilla A.A., Bibby S., Venugopal H., Harrison J.J., Traves R.J., Hall R.A., Hobson-Peters J., Coulibaly F., Watterson D. (2021) The structure of an infectious immature flavivirus redefines viral architecture and maturation. Science Advances 7 (20) eabe4507 https://doi.org/10.1126/sciadv.abe4507
Curvello R., Alves D., Abud H.E., Garnier G. (2021) A thermo-responsive collagen-nanocellulose hydrogel for the growth of intestinal organoids. Materials Science and Engineering C 124. 112051 https://doi.org/10.1016/j.msec.2021.112051
Kamaliya B., Garg V., Liu A.C.Y., Chen Y., Aslam M., Fu J., Mote R.G. (2021) Tailoring Surface Self-Organization for Nanoscale Polygonal Morphology on Germanium. Advanced Materials 33 (21) 2008668 https://doi.org/10.1002/adma.202008668
Maliha M., Brammananth R., Dyson J., Coppel R.L., Werrett M., Andrews P.C., Batchelor W. (2021) Biocompatibility and selective antibacterial activity of a bismuth phosphinato-nanocellulose hydrogel. Cellulose 28 (8) 4701 https://doi.org/10.1007/s10570-021-03835-5
Conduit S.E., Davies E.M., Fulcher A.J., Oorschot V., Mitchell C.A. (2021) Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone. Frontiers in Cell and Developmental Biology 9, 634649 https://doi.org/10.3389/fcell.2021.634649
Vidallon M.L.P., Giles L.W., Crawford S., Bishop A.I., Tabor R.F., de Campo L., Teo B.M. (2021) Exploring the transition of polydopamine-shelled perfluorohexane emulsion droplets into microbubbles using small- And ultra-small-angle neutron scattering. Physical Chemistry Chemical Physics 23 (16) 9843 https://doi.org/10.1039/d1cp01146d
Korneev D., Merriner D.J., Gervinskas G., de Marco A., O’Bryan M.K. (2021) New Insights Into Sperm Ultrastructure Through Enhanced Scanning Electron Microscopy. Frontiers in Cell and Developmental Biology 9, 672592 https://doi.org/10.3389/fcell.2021.672592
Josephs T.M., Belousoff M.J., Liang Y.-L., Piper S.J., Cao J., Garama D.J., Leach K., Gregory K.J., Christopoulos A., Hay D.L., Danev R., Wootten D., Sexton P.M. (2021) Structure and dynamics of the CGRP receptor in apo and peptide-bound forms. Science 372 (6538) eabf7258 https://doi.org/10.1126/SCIENCE.ABF7258
Vidallon M.L.P., Tabor R.F., Bishop A.I., Teo B.M. (2021) Ultrasound-assisted fabrication of acoustically active, erythrocyte membrane “bubbles”. Ultrasonics Sonochemistry 72, 105429 https://doi.org/10.1016/j.ultsonch.2020.105429
Loughlin F.E., West D.L., Gunzburg M.J., Waris S., Crawford S.A., Wilce M.C.J., Wilce J.A. (2021) Tandem RNA binding sites induce self-Association of the stress granule marker protein TIA-1. Nucleic Acids Research 49 (5) 2403 https://doi.org/10.1093/nar/gkab080
Ratnayake D., Nguyen P.D., Rossello F.J., Wimmer V.C., Tan J.L., Galvis L.A., Julier Z., Wood A.J., Boudier T., Isiaku A.I., Berger S., Oorschot V., Sonntag C., Rogers K.L., Marcelle C., Lieschke G.J., Martino M.M., Bakkers J., Currie P.D. (2021) Macrophages provide a transient muscle stem cell niche via NAMPT secretion. Nature 591 (7849) 281 https://doi.org/10.1038/s41586-021-03199-7
Carthew J., Abdelmaksoud H.H., Hodgson-Garms M., Aslanoglou S., Ghavamian S., Elnathan R., Spatz J.P., Brugger J., Thissen H., Voelcker N.H., Cadarso V.J., Frith J.E. (2021) Precision Surface Microtopography Regulates Cell Fate via Changes to Actomyosin Contractility and Nuclear Architecture. Advanced Science 8 (6) 2003186 https://doi.org/10.1002/advs.202003186
Malerba M.E., Marshall D.J., Palacios M.M., Raven J.A., Beardall J. (2021) Cell size influences inorganic carbon acquisition in artificially selected phytoplankton. New Phytologist 229 (5) 2647 https://doi.org/10.1111/nph.17068
Pourabed A., Younas T., Liu C., Shanbhag B.K., He L., Alan T. (2021) High throughput acoustic microfluidic mixer controls self-assembly of protein nanoparticles with tuneable sizes. Journal of Colloid and Interface Science 585, 229 https://doi.org/10.1016/j.jcis.2020.11.070
Zhou S., Bhukya H., Malet N., Harrison P.J., Rea D., Belousoff M.J., Venugopal H., Sydor P.K., Styles K.M., Song L., Cryle M.J., Alkhalaf L.M., Fülöp V., Challis G.L., Corre C. (2021) Molecular basis for control of antibiotic production by a bacterial hormone. Nature 590 (7846) 463 https://doi.org/10.1038/s41586-021-03195-x
Gordillo Altamirano F., Forsyth J.H., Patwa R., Kostoulias X., Trim M., Subedi D., Archer S.K., Morris F.C., Oliveira C., Kielty L., Korneev D., O’Bryan M.K., Lithgow T.J., Peleg A.Y., Barr J.J. (2021) Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials. Nature Microbiology 6 (2) 157 https://doi.org/10.1038/s41564-020-00830-7
Cullen C.L., Pepper R.E., Clutterbuck M.T., Pitman K.A., Oorschot V., Auderset L., Tang A.D., Ramm G., Emery B., Rodger J., Jolivet R.B., Young K.M. (2021) Periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain. Cell Reports 34 (3) 108641 https://doi.org/10.1016/j.celrep.2020.108641
Mohamed A., Chan H., Luhur J., Bauda E., Gallet B., Morlot C., Cole L., Awad M., Crawford S., Lyras D., Rudner D.Z., Rodrigues C.D.A. (2021) Chromosome Segregation and Peptidoglycan Remodeling Are Coordinated at a Highly Stabilized Septal Pore to Maintain Bacterial Spore Development. Developmental Cell 56 (1) 36 https://doi.org/10.1016/j.devcel.2020.12.006
McGrath M.J., Eramo M.J., Gurung R., Sriratana A., Gehrig S.M., Lynch G.S., Lourdes S.R., Koentgen F., Feeney S.J., Lazarou M., McLean C.A., Mitchell C.A. (2021) Defective lysosome reformation during autophagy causes skeletal muscle disease. Journal of Clinical Investigation 131 (1) e135124 https://doi.org/10.1172/JCI135124
Adamus K., Reboul C., Voss J., Huang C., Schittenhelm R.B., Le S.N., Ellisdon A.M., Elmlund H., Boudes M., Elmlund D. (2021) SAGA and SAGA-like SLIK transcriptional coactivators are structurally and biochemically equivalent. Journal of Biological Chemistry 296, 100671 https://doi.org/10.1016/j.jbc.2021.100671
Gully B.S., Venugopal H., Fulcher A.J., Fu Z., Li J., Deuss F.A., Llerena C., Heath W.R., Lahoud M.H., Caminschi I., Rossjohn J., Berry R. (2021) The cryo-EM structure of the endocytic receptor DEC-205. Journal of Biological Chemistry 296, 100127 https://doi.org/10.1074/jbc.RA120.016451
Malcolm T.R., Belousoff M.J., Venugopal H., Borg N.A., Drinkwater N., Atkinson S.C., McGowan S. (2021) Active site metals mediate an oligomeric equilibrium in Plasmodium M17 aminopeptidases. Journal of Biological Chemistry 296, 100173 https://doi.org/10.1074/jbc.RA120.016313
Spicer B.A., Dunstone M.A. (2021) Going full circle: Determining the structures of complement component 9. Methods in Enzymology 649, 103 https://doi.org/10.1016/bs.mie.2021.01.020
Ruparelia A.A., McKaige E.A., Williams C., Schulze K.E., Fuchs M., Oorschot V., Lacene E., Meregalli M., Lee C., Serrano R.J., Baxter E.C., Monro K., Torrente Y., Ramm G., Stojkovic T., Lavoie J.N., Bryson-Richardson R.J. (2021) Metformin rescues muscle function in BAG3 myofibrillar myopathy models. Autophagy 17 (9) 2494 https://doi.org/10.1080/15548627.2020.1833500
Shubin A.V., Komissarov A.A., Karaseva M.A., Padman B.S., Kostrov S.V., Demidyuk I.V. (2021) Human hepatitis A virus 3C protease exerts a cytostatic effect on Saccharomyces cerevisiae and affects the vacuolar compartment. Biologia 76 (1) 321 https://doi.org/10.2478/s11756-020-00569-w
Sylvain Garciaz, Sebastian Müller, Andrew Guirguis, Fiona C Brown, Yih-Chih Chan, Mathilde Poplineau, Kevin Tran, Kah-Lok Chan, Laura MacPherson, Brian Liddicoat, Enid YN Lam, Tatiana Cañeque, Marian L Burr, Veronique Litalien, Giovanna Pomilio, Estelle Duprez, David Huang, Sarah-Jane Dawson, Georg Ramm, Andrew G Cox, Kristin K Brown, Andrew H Wei, Kate McArthur, Raphael Rodriguez, Mark A Dawson (2021) Pharmacological Reduction of Mitochondrial Iron in AML Triggers a BAX/BAK Dependent Non-Canonical Cell Death Synergistic with Venetoclax. Blood 138 (supplement 1) 267 https://doi.org/10.1182/blood-2021-145424
Viola Oorschot, Jill Danne, Benjamin Lindsey, Jan Kaslin, Georg Ramm (2021) Immuno-correlative light and electron microscopy (iCLEM) using STEM. protocols.io https://doi.org/10.17504/protocols.io.bv89n9z6
Shi Qiu, Gediminas Gervinskas, Hariprasad Venugopal, Ross Marceau, Jing Fu (2021) Graphene encapsulation enables vitreous ice sample for APT and near-atomic reconstruction of nanoparticle-liquid interface. Microscopy and Microanalysis 27 (S1) 1270 https://doi.org/10.1017/S1431927621004761
Radostin Danev, Matthew Belousoff, Yi-Lynn Liang, Xin Zhang, Fabian Eisenstein, Denise Wootten, Patrick M Sexton (2021) Routine sub-2.5 Å cryo-EM structure determination of GPCRs. Nature Communications 12 (1) 4333 https://doi.org/10.1038/s41467-021-24650-3
Xin Zhang, Matthew J Belousoff, Yi-Lynn Liang, Radostin Danev, Patrick M Sexton, Denise Wootten (2021) Structure and dynamics of semaglutide-and taspoglutide-bound GLP-1R-Gs complexes. Cell Reports 36 (2) 109374 https://doi.org/10.1016/j.celrep.2021.109374
CL Cullen, RE Pepper, M Clutterbuck, K Pitman, V Oorschot, L Auderset, A Tang, G Ramm, B Emery, J Rodger, RB Jolivet, KM Young (2021) Learning induces periaxonal and nodal plasticity in the adult mouse brain. Glia 69, E376
Christopher J Lupton, Charles Bayly-Jones, Laura D’Andrea, Cheng Huang, Ralf B Schittenhelm, Hari Venugopal, James C Whisstock, Michelle L Halls, Andrew M Ellisdon (2021) The cryo-EM structure of the neurofibromin dimer reveals the molecular basis for von Recklinghausen disease. Biorxiv https://doi.org/10.1101/2021.02.18.431788
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, Iannis E Adamopoulos, Khosrow Adeli, Timon E Adolph, Annagrazia Adornetto, Elma Aflaki, Galila Agam, Anupam Agarwal, Bharat B Aggarwal, Maria Agnello, Patrizia Agostinis, Javed N Agrewala, Alexander Agrotis, Patricia V Aguilar, S Tariq Ahmad, Zubair M Ahmed, Ulises Ahumada-Castro, Sonja Aits, Shu Aizawa, Yunus Akkoc, Tonia Akoumianaki, Hafize Aysin Akpinar, Ahmed M Al-Abd, Lina Al-Akra, Abeer Al-Gharaibeh, Moulay A Alaoui-Jamali, Simon Alberti, Elísabet Alcocer-Gómez, Cristiano Alessandri, Muhammad Ali, M Abdul Alim Al-Bari, Saeb Aliwaini, Javad Alizadeh, Eugènia Almacellas, Alexandru Almasan, Alicia Alonso, Guillermo D Alonso, Nihal Altan-Bonnet, Dario C Altieri, Élida MC Álvarez, Sara Alves, Cristine Alves da Costa, Mazen M Alzaharna, Marialaura Amadio, Consuelo Amantini, Cristina Amaral, Susanna Ambrosio, Amal O Amer, Veena Ammanathan, Zhenyi An, Stig U Andersen, Shaida A Andrabi, Magaiver Andrade-Silva, Allen M Andres, Sabrina Angelini, David Ann, Uche C Anozie, Mohammad Y Ansari, Pedro Antas, Adam Antebi, Zuriñe Antón, Tahira Anwar, Lionel Apetoh, Nadezda Apostolova, Toshiyuki Araki, Yasuhiro Araki, Kohei Arasaki, Wagner L Araújo, Jun Araya, Catherine Arden, Maria-Angeles Arévalo, Sandro Arguelles, Esperanza Arias, Jyothi Arikkath, Hirokazu Arimoto, Aileen R Ariosa, Darius Armstrong-James, Laetitia Arnauné-Pelloquin, Angeles Aroca, Daniela S Arroyo, Ivica Arsov, Rubén Artero, Dalia Maria Lucia Asaro, Michael Aschner, Milad Ashrafizadeh, Osnat Ashur-Fabian, Atanas G Atanasov, Alicia K Au, Patrick Auberger, Holger W Auner, Laure Aurelian, Riccardo Autelli, Laura Avagliano, Yenniffer Ávalos, Sanja Aveic, Célia Alexandra Aveleira, Tamar Avin-Wittenberg, Yucel Aydin, Scott Ayton, Srinivas Ayyadevara, Maria Azzopardi, Misuzu Baba, Jonathan M Backer, Steven K Backues, Dong-Hun Bae, Ok-Nam Bae, Soo Han Bae, Eric H Baehrecke, Ahruem Baek, Seung-Hoon Baek, Sung Hee Baek, Giacinto Bagetta, Agnieszka Bagniewska-Zadworna, Hua Bai, Jie Bai, Xiyuan Bai, Yidong Bai, Nandadulal Bairagi, Shounak Baksi, Teresa Balbi, Cosima T Baldari, Walter Balduini, Andrea Ballabio, Maria Ballester, Salma Balazadeh, Rena Balzan, Rina Bandopadhyay, Sreeparna Banerjee, Sulagna Banerjee, Ágnes Bánréti, Yan Bao, Mauricio S Baptista, Alessandra Baracca, Cristiana Barbati, Ariadna Bargiela, Daniela Barilà, Peter G Barlow, Sami J Barmada, Esther Barreiro, George E Barreto, Jiri Bartek (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy 17 (1) 1 https://doi.org/10.1080/15548627.2020.1797280
-
Luhur J., Chan H., Kachappilly B., Mohamed A., Morlot C., Awad M., Lyras D., Taib N., Gribaldo S., Rudner D.Z., Rodrigues C.D.A. (2020) A dynamic, ring-forming MucB / RseB-like protein influences spore shape in Bacillus subtilis. PLoS Genetics 16 (12) e1009246. https://doi.org/10.1371/journal.pgen.1009246
Tullett K.M., Tan P.S., Park H.-Y., Schittenhelm R.B., Michael N., Li R., Policheni A.N., Gruber E., Huang C., Fulcher A.J., Danne J.C., Czabotar P.E., Wakim L.M., Mintern J.D., Ramm G., Radford K.J., Caminschi I., O’Keeffe M., Villadangos J.A., Wright M.D., Blewitt M.E., Heath W.R., Shortman K., Purcel A.W., Nicola N.A., Zhang J.-G., Lahoud M.H. (2020) RNF41 regulates the damage recognition receptor Clec9a and antigen cross-presentation in mouse dendritic cells. eLife 9, e63452. https://doi.org/10.7554/eLife.63452
Dong M., Deganutti G., Piper S.J., Liang Y.-L., Khoshouei M., Belousoff M.J., Harikumar K.G., Reynolds C.A., Glukhova A., Furness S.G.B., Christopoulos A., Danev R., Wootten D., Sexton P.M., Miller L.J. (2020) Structure and dynamics of the active Gs-coupled human secretin receptor. Nature Communications 11 (1) 4137. https://doi.org/10.1038/s41467-020-17791-4
Hardy J.M., Dunstan R.A., Grinter R., Belousoff M.J., Wang J., Pickard D., Venugopal H., Dougan G., Lithgow T., Coulibaly F. (2020) The architecture and stabilisation of flagellotropic tailed bacteriophages. Nature Communications 11 (1) 3748. https://doi.org/10.1038/s41467-020-17505-w
Quinn K.M., Hussain T., Kraus F., Formosa L.E., Lam W.K., Dagley M.J., Saunders E.C., Assmus L.M., Wynne-Jones E., Loh L., van de Sandt C.E., Cooper L., Good-Ja. cobson K.L., Kedzierska K., Mackay L.K., McConville M.J., Ramm G., Ryan M.T., La Gruta N.L. (2020) Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality. Nature Communications 11 (1) 2857. https://doi.org/10.1038/s41467-020-16633-7
Gao Y., Xu J., Zhang C., Venugopal H., Kermaniyan S.S., Such G., Ritchie C. (2020) Rationale Design of pH-Responsive Core-Shell Nanoparticles: Polyoxometalate-Mediated Structural Reorganization. ACS Applied Nano Materials 3 (11) 11247. https://doi.org/10.1021/acsanm.0c02365
Zhang X., Belousoff M.J., Zhao P., Kooistra A.J., Truong T.T., Ang S.Y., Underwood C.R., Egebjerg T., Šenel P., Stewart G.D., Liang Y.-L., Glukhova A., Venugopal H., Christopoulos A., Furness S.G.B., Miller L.J., Reedtz-Runge S., Langmead C.J., Gloriam D.E., Danev R., Sexton P.M., Wootten D. (2020) Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Molecular Cell 80 (3) 485. https://doi.org/10.1016/j.molcel.2020.09.020
Jones L.K., Lam R., McKee K.K., Aleksandrova M., Dowling J., Alexander S.I., Mallawaarachchi A., Cottle D.L., Short K.M., Pais L., Miner J.H., Mallett A.J., Simons C., McCarthy H., Yurchenco P.D., Smyth I.M. (2020) A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder. Development (Cambridge) 147 (21). https://doi.org/10.1242/dev.189183
Qu Y., McGiffin D., Hayward C., McLean J., Duncan C., Robson D., Kure C., Shen R., Williams H., Mayo S., Thissen H., Marasco S., Zimmet A., Negri J., Jansz P., Dhital K., Kaye D.M., Peleg A.Y. (2020) Characterization of infected, explanted ventricular assist device drivelines: The role of biofilms and microgaps in the driveline tunnel. Journal of Heart and Lung Transplantation 39 (11) 1289. https://doi.org/10.1016/j.healun.2020.07.015
Bayly-Jones C., Pang S.S., Spicer B.A., Whisstock J.C., Dunstone M.A. (2020) Ancient but Not Forgotten: New Insights Into MPEG1, a Macrophage Perforin-Like Immune Effector. Frontiers in Immunology 11, 581906. https://doi.org/10.3389/fimmu.2020.581906
Bakheet B., Prodanovic V., Deletic A., McCarthy D. (2020) Effective treatment of greywater via green wall biofiltration and electrochemical disinfection. Water research 185, 116228. https://doi.org/10.1016/j.watres.2020.116228
Zeng X., Liu Y., Xia Y., Uddin M.H., Xia D., McCarthy D.T., Deletic A., Yu J., Zhang X. (2020) Cooperatively modulating reactive oxygen species generation and bacteria-photocatalyst contact over graphitic carbon nitride by polyethylenimine for rapid water disinfection. Applied Catalysis B: Environmental 274, 119095. https://doi.org/10.1016/j.apcatb.2020.119095
Awad M.M., Hutton M.L., Quek A.J., Klare W.P., Mileto S.J., Mackin K., Ly D., Oorschot V., Bosnjak M., Jenkin G., Conroy P.J., West N., Fulcher A., Costin A., Day C.J., Jennings M.P., Medcalf R.L., Sanderson-Smith M., Cordwell S.J., Law R.H.P., Whisstock J.C., Lyras D. (2020) Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface. Gastroenterology 159 (4) 1431. https://doi.org/10.1053/j.gastro.2020.06.032
Kumar S., Jain A., Choi S.W., da Silva G.P.D., Allers L., Mudd M.H., Peters R.S., Anonsen J.H., Rusten T.-E., Lazarou M., Deretic V. (2020) Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens (Nature Cell Biology, (2020), 22, 8, (973-985), 10.1038/s41556-020-0549-1). Nature Cell Biology 22 (10) 1286 https://doi.org/10.1038/s41556-020-0574-0
Aslanoglou S., Chen Y., Oorschot V., Trifunovic Z., Hanssen E., Suu K., Voelcker N.H., Elnathan R. (2020) Efficient Transmission Electron Microscopy Characterization of Cell-Nanostructure Interfacial Interactions. Journal of the American Chemical Society 142 (37) 15649. https://doi.org/10.1021/jacs.0c05919
Qiu S., Zheng C., Zhou Q., Dong D., Shi Q., Garg V., Cheng W., Marceau R.K.W., Sha G., Fu J. (2020) Direct Imaging of Liquid-Nanoparticle Interfaces with Atom Probe Tomography. Journal of Physical Chemistry C 124 (35) 19389. https://doi.org/10.1021/acs.jpcc.0c05504
Aghaei-Ghareh-Bolagh B., Mukherjee S., Lockley K.M., Mithieux S.M., Wang Z., Emmerson S., Darzi S., Gargett C.E., Weiss A.S. (2020) A novel tropoelastin-based resorbable surgical mesh for pelvic organ prolapse repair. Materials Today Bio 8 (100081) https://doi.org/10.1016/j.mtbio.2020.100081
Turner D.L., Korneev D.V., Purdy J.G., de Marco A., Mathias R.A. (2020) The host exosome pathway underpins biogenesis of the human cytomegalovirus virion. eLife 9 (e58288) https://doi.org/10.7554/ELIFE.58288
Acter S., Vidallon M.L.P., Crawford S., Tabor R.F., Teo B.M. (2020) Efficient Cellular Internalization and Transport of Bowl-Shaped Polydopamine Particles. Particle and Particle Systems Characterization 37 (9) 2000166 https://doi.org/10.1002/ppsc.202000166
Qiu S., Garg V., Zhang S., Chen Y., Li J., Taylor A., Marceau R.K.W., Fu J. (2020) Graphene encapsulation enabled high-throughput atom probe tomography of liquid specimens. Ultramicroscopy 216 (113036) https://doi.org/10.1016/j.ultramic.2020.113036
Beckham S.A., Matak M.Y., Belousoff M.J., Venugopal H., Shah N., Vankadari N., Elmlund H., Nguyen J.H.C., Semler B.L., Wilce M.C.J., Wilce J.A. (2020) Structure of the PCBP2/stem-loop IV complex underlying translation initiation mediated by the poliovirus type i IRES. Nucleic Acids Research 48 (14) 8006 https://doi.org/10.1093/nar/gkaa519
Vu M.N., Kelly H.G., Wheatley A.K., Peng S., Pilkington E.H., Veldhuis N.A., Davis T.P., Kent S.J., Truong N.P. (2020) Cellular Interactions of Liposomes and PISA Nanoparticles during Human Blood Flow in a Microvascular Network. Small 16 (33) 2002861 https://doi.org/10.1002/smll.202002861
Selvadurai M.V., Moon M.J., Mountford S.J., Ma X., Zheng Z., Jennings I.G., Setiabakti N.M., Iman R.P., Brazilek R.J., Abidin N.A.Z., Chicanne G., Severin S., Nicholls A.J., Wong C.H.Y., Rinckel J.-Y., Eckly A., Gachet C., Nesbitt W.S., Thompson P.E., Hamilton J.R. (2020) Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation. Science Translational Medicine 12 (553) eaar8430 https://doi.org/10.1126/SCITRANSLMED.AAR8430
Chang R., Zhang X., Qiao A., Dai A., Belousoff M.J., Tan Q., Shao L., Zhong L., Lin G., Liang Y.-L., Ma L., Han S., Yang D., Danev R., Wang M.-W., Wootten D., Wu B., Sexton P.M. (2020) Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide. Journal of Biological Chemistry 295 (28) 9313 https://doi.org/10.1074/jbc.ra120.013793
Xu Y., Kirk N.S., Venugopal H., Margetts M.B., Croll T.I., Sandow J.J., Webb A.I., Delaine C.A., Forbes B.E., Lawrence M.C. (2020) How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. Structure 28 (7) 9313 https://doi.org/10.1016/j.str.2020.05.002
Zhao C., Zhang H., Hou J., Ou R., Zhu Y., Li X., Jiang L., Wang H. (2020) Effect of Anion Species on Ion Current Rectification Properties of Positively Charged Nanochannels. ACS Applied Materials and Interfaces 12 (25) 28915 https://doi.org/10.1021/acsami.0c08263
Kochan K., Nethercott C., Taghavimoghaddam J., Richardson Z., Lai E., Crawford S.A., Peleg A.Y., Wood B.R., Heraud P. (2020) Rapid Approach for Detection of Antibiotic Resistance in Bacteria Using Vibrational Spectroscopy. Analytical Chemistry 92 (12) 8235 https://doi.org/10.1021/acs.analchem.0c00474
Wright A., Deane-Alder K., Marschall E., Bamert R., Venugopal H., Lithgow T., Lupton D.W., Belousoff M.J. (2020) Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM. ACS Pharmacology and Translational Science 3 (3) 425 https://doi.org/10.1021/acsptsci.0c00041
Hussein M., Schneider-Futschik E.K., Paulin O.K.A., Allobawi R., Crawford S., Zhou Q.T., Hanif A., Baker M., Zhu Y., Li J., Velkov T. (2020) Effective Strategy Targeting Polymyxin-Resistant Gram-Negative Pathogens: Polymyxin B in Combination with the Selective Serotonin Reuptake Inhibitor Sertraline. ACS Infectious Diseases 6 (6) 1436 https://doi.org/10.1021/acsinfecdis.0c00108
Wan J., Fan B., Liu Y., Hsia T., Qin K., Junkers T., Teo B.M., Thang S.H. (2020) Room temperature synthesis of block copolymer nano-objects with different morphologies: via ultrasound initiated RAFT polymerization-induced self-assembly (sono-RAFT-PISA). Polymer Chemistry 11 (21) 3564 https://doi.org/10.1039/d0py00461h
Paul K., Darzi S., Werkmeister J.A., Gargett C.E., Mukherjee S. (2020) Emerging nano/micro-structured degradable polymeric meshes for pelvic floor reconstruction. Nanomaterials 10 (6) 1120 https://doi.org/10.3390/nano10061120
Chen Y., Aslanoglou S., Murayama T., Gervinskas G., Fitzgerald L.I., Sriram S., Tian J., Johnston A.P.R., Morikawa Y., Suu K., Elnathan R., Voelcker N.H. (2020) Silicon-Nanotube-Mediated Intracellular Delivery Enables Ex Vivo Gene Editing. Advanced Materials 32 (24) 200036 https://doi.org/10.1002/adma.202000036
Qu Y., Li Y., Cameron D.R., Easton C.D., Zhu X., Zhu M., Salwiczek M., Muir B.W., Thissen H., Daley A., Forsythe J.S., Peleg A.Y., Lithgow T. (2020) Hyperosmotic Infusion and Oxidized Surfaces Are Essential for Biofilm Formation of Staphylococcus capitis From the Neonatal Intensive Care Unit. Frontiers in Microbiology 11, 920 https://doi.org/10.3389/fmicb.2020.00920
Fan B., Liu Y., Wan J., Crawford S., Thang S.H. (2020) Polymerization-Induced Self-Assembly (PISA) and "host-Guest" Complexation-Directed Polymer/Gold Nanocomposites. ACS Materials Letters 2 (5) 492 https://doi.org/10.1021/acsmaterialslett.0c00043
Buckley G., Gervinskas G., Taveneau C., Venugopal H., Whisstock J.C., de Marco A. (2020) Automated cryo-lamella preparation for high-throughput in-situ structural biology. Journal of Structural Biology 210 (2) 107488 https://doi.org/10.1016/j.jsb.2020.107488
Liu Y., Zeng X., Easton C.D., Li Q., Xia Y., Yin Y., Hu X., Hu J., Xia D., McCarthy D.T., Deletic A., Sun C., Yu J., Zhang X. (2020) An: In situ assembled WO3-TiO2 vertical heterojunction for enhanced Z-scheme photocatalytic activity. Nanoscale 12 (16) 8775 https://doi.org/10.1039/d0nr01611j
Liang Y.-L., Belousoff M.J., Fletcher M.M., Zhang X., Khoshouei M., Deganutti G., Koole C., Furness S.G.B., Miller L.J., Hay D.L., Christopoulos A., Reynolds C.A., Danev R., Wootten D., Sexton P.M. (2020) Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins. ACS Pharmacology and Translational Science 3 (2) 263 https://doi.org/10.1021/acsptsci.9b00080
Qiu S., Zheng C., Garg V., Chen Y., Gervinskas G., Li J., Dunstone M.A., Marceau R.K.W., Fu J. (2020) Three-Dimensional Chemical Mapping of a Single Protein in the Hydrated State with Atom Probe Tomography. Analytical Chemistry 92 (7) 5168 https://doi.org/10.1021/acs.analchem.9b05668
Mukherjee S., Darzi S., Paul K., Cousins F.L., Werkmeister J.A., Gargett C.E. (2020) Electrospun Nanofiber Meshes With Endometrial MSCs Modulate Foreign Body Response by Increased Angiogenesis, Matrix Synthesis, and Anti-Inflammatory Gene Expression in Mice: Implication in Pelvic Floor. Frontiers in Pharmacology 11, 353 https://doi.org/10.3389/fphar.2020.00353
Stephens L.J., Munuganti S., Duffin R.N., Werrett M.V., Andrews P.C. (2020) Is Bismuth Really the "green" Metal? Exploring the Antimicrobial Activity and Cytotoxicity of Organobismuth Thiolate Complexes. Inorganic Chemistry 59 (6) 3494 https://doi.org/10.1021/acs.inorgchem.9b03550
Liang Y.-L., Belousoff M.J., Zhao P., Koole C., Fletcher M.M., Truong T.T., Julita V., Christopoulos G., Xu H.E., Zhang Y., Khoshouei M., Christopoulos A., Danev R., Sexton P.M., Wootten D. (2020) Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation. Molecular Cell 77 (3) 656 https://doi.org/10.1016/j.molcel.2020.01.012
Li J., Sun Y.B.Y., Chen W., Fan J., Li S., Qu X., Chen Q., Chen R., Zhu D., Zhang J., Wu Z., Chi H., Crawford S., Oorschot V., Puelles V.G., Kerr P.G., Ren Y., Nilsson S.K., Christian M., Tang H., Chen W., Bertram J.F., Nikolic-Paterson D.J., Yu X. (2020) Smad4 promotes diabetic nephropathy by modulating glycolysis and OXPHOS. EMBO Reports 21 (2) e48781 https://doi.org/10.15252/embr.201948781
De Winter J.M., Molenaar J.P., Yuen M., Van Der Pijl R., Shen S., Conijn S., Van De Locht M., Willigenburg M., Bogaards S.J.P., Van Kleef E.S.B., Lassche S., Persson M., Rassier D.E., Sztal T.E., Ruparelia A.A., Oorschot V., Ramm G., Hall T.E., Xiong Z., Johnson C.N., Li F., Kiss B., Lozano-Vidal N., Boon R.A., Marabita M., Nogara L., Blaauw B., Rodenburg R.J., Küsters B., Doorduin J., Beggs A.H., Granzier H., Campbell K., Ma W., Irving T., Malfatti E., Romero N.B., Bryson-Richardson R.J., Van Engelen B.G.M., Voermans N.C., Ottenheijm C.A.C. (2020) KBTBD13 is an actin-binding protein that modulates muscle kinetics. Journal of Clinical Investigation 130 (2) 754 https://doi.org/10.1172/JCI124000
Zhao P., Liang Y.-L., Belousoff M.J., Deganutti G., Fletcher M.M., Willard F.S., Bell M.G., Christe M.E., Sloop K.W., Inoue A., Truong T.T., Clydesdale L., Furness S.G.B., Christopoulos A., Wang M.-W., Miller L.J., Reynolds C.A., Danev R., Sexton P.M., Wootten D. (2020) Activation of the GLP-1 receptor by a non-peptidic agonist. Nature 577 (7790) 432 https://doi.org/10.1038/s41586-019-1902-z
Fischer T.D., Wang C., Padman B.S., Lazarou M., Youle R.J. (2020) STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain. Journal of Cell Biology 219 (12) e202009128 https://doi.org/10.1083/JCB.202009128
Hussein M., Hu X., Paulin O.K.A., Crawford S., Tony Zhou Q., Baker M., Schneider-Futschik E.K., Zhu Y., Li J., Velkov T. (2020) Polymyxin B combinations with FDA-approved non-antibiotic phenothiazine drugs targeting multi-drug resistance of Gram-negative pathogens. Computational and Structural Biotechnology Journal 18, 2247 https://doi.org/10.1016/j.csbj.2020.08.008
Colmant A.M.G., O'Brien C.A., Newton N.D., Watterson D., Hardy J., Coulibaly F., Bielefeldt-Ohmann H., Warrilow D., Huang B., Paramitha D., Harrison J.J., Hall R.A., Hobson-Peters J. (2020) Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restriction. Journal of General Virology 101 (4) 440 https://doi.org/10.1099/JGV.0.001388
Carpinelli M.R., De Vries M.E., Auden A., Butt T., Deng Z., Partridge D.D., Miles L.B., Georgy S.R., Haigh J.J., Darido C., Brabletz S., Brabletz T., Stemmler M.P., Dworkin S., Jane S.M. (2020) Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure. DMM Disease Models and Mechanisms 13 (3) dmm042218 https://doi.org/10.1242/dmm.042218
Lindblom R.S.J., Higgins G.C., Nguyen T.-V., Arnstein M., Henstridge D.C., Granata C., Snelson M., Thallas-Bonke V., Cooper M.E., Forbes J.M., Coughlan M.T. (2020) Delineating a role for the mitochondrial permeability transition pore in diabetic kidney disease by targeting cyclophilin D. Clinical Science 134 (2) 239 https://doi.org/10.1042/CS20190787
Tess R Malcolm, Matthew J Belousoff, Hariprasad Venugopal, Natalie A Borg, Nyssa Drinkwater, Sarah C Atkinson, Sheena McGowan (2020) Metal Dependent Dynamic Equilibrium: A Regulatory Mechanism for M17 Aminopeptidases from Plasmodium falciparum and Plasmodium vivax. bioRxiv https://doi.org/10.1101/2020.10.08.331538
Shahinur Acter, Mark Louis P Vidallon, Simon Crawford, Rico F Tabor, Boon Mian Teo (2020) Polydopamine Nanoparticles: Efficient Cellular Internalization and Transport of Bowl‐Shaped Polydopamine Particles. Particle & Particle Systems Characterization 37 (9) 2070020 https://doi.org/10.1002/ppsc.202070020
Radostin Danev, Matthew Belousoff, Yi-Lynn Liang, Xin Zhang, Denise Wootten, Patrick M Sexton (2020) Routine sub-2.5 Å cryo-EM structure determination of B-family G protein-coupled receptors. BioRxiv https://doi.org/10.1101/2020.08.21.260851
Shi Qiu, Yu Chen, Gediminas Gervinskas, Ross KW Marceau, Changxi Zheng, Gang Sha, Jing Fu (2020) Graphene nanopipette enabled liquid delivery at zeptoliter precision. arXiv https://doi.org/10.48550/arXiv.2008.08254
Ilia Banakh, Perdita Cheshire, Mostafizur Rahman, Irena Carmichael, Premlatha Jagadeesan, Neil R Cameron, Heather Cleland, Shiva Akbarzadeh (2020) A comparative study of engineered dermal templates for skin wound repair in a mouse model. International Journal of Molecular Sciences 21 (12) 4508 https://doi.org/10.3390/ijms21124508
Shanshan Zhou, Hussain Bhukya, Nicolas Malet, Peter J Harrison, Dean Rea, Matthew J Belousoff, Hariprasad Venugopal, Paulina K Sydor, Kathryn M Styles, Lijiang Song, Max J Cryle, Lona M Alkhalaf, Vilmos Fülöp, Gregory L Challis, Christophe Corre (2020) Structural basis for control of antibiotic production by bacterial hormones. bioRxiv https://doi.org/10.1101/2020.05.02.073981
S Petratos, MJ Kim, JY Lee, T Bedford, P Theotokis, V Oorschot, G Ramm, CS Tremblay, DJ Curtis, SM Strittmatter (2020) NgR-Fc protein delivered by hematopoietic cells enhances neurorepair in a multiple sclerosis model. Multiple Sclerosis Journal 26 (3)
Peishen Zhao, Yi-Lynn Liang, Matthew J Belousoff, Giuseppe Deganutti, Madeleine M Fletcher, Francis S Willard, Michael G Bell, Michael E Christe, Kyle W Sloop, Asuka Inoue, Tin T Truong, Lachlan Clydesdale, Sebastian GB Furness, Arthur Christopoulos, Ming-Wei Wang, Laurence J Miller, Christopher A Reynolds, Radostin Danev, Patrick M Sexton, Denise Wootten (2020) The molecular basis for sugar import in malaria parasites. Nature 578 (7794) 321 https://doi.org/10.1038/s41586-020-1963-z
-
Pang S.S., Bayly-Jones C., Radjainia M., Spicer B.A., Law R.H.P., Hodel A.W., Parsons E.S., Ekkel S.M., Conroy P.J., Ramm G., Venugopal H., Bird P.I., Hoogenboom B.W., Voskoboinik I., Gambin Y., Sierecki E., Dunstone M.A., Whisstock J.C. (2019) The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nature Communications 10 (1) 4288. https://doi.org/10.1038/s41467-019-12279-2
Chen Y., Aslanoglou S., Gervinskas G., Abdelmaksoud H., Voelcker N.H., Elnathan R. (2019) Cellular Deformations Induced by Conical Silicon Nanowire Arrays Facilitate Gene Delivery. Small 15 (47) 1904819. https://doi.org/10.1002/smll.201904819
Desfosses A., Venugopal H., Joshi T., Felix J., Jessop M., Jeong H., Hyun J., Heymann J.B., Hurst M.R.H., Gutsche I., Mitra A.K. (2019) Atomic structures of an entire contractile injection system in both the extended and contracted states. Nature Microbiology 4 (11) 1885. https://doi.org/10.1038/s41564-019-0530-6
Paul K., Darzi S., McPhee G., Del Borgo M.P., Werkmeister J.A., Gargett C.E., Mukherjee S. (2019) 3D bioprinted endometrial stem cells on melt electrospun poly ε-caprolactone mesh for pelvic floor application promote anti-inflammatory responses in mice. Acta Biomaterialia https://doi.org/10.1016/j.actbio.2019.08.003
Xiao Y., Liu Q., Clulow A.J., Li T., Manohar M., Gilbert E.P., de Campo L., Hawley A., Boyd B.J. (2019) PEGylation and surface functionalization of liposomes containing drug nanocrystals for cell-targeted delivery. Colloids and Surfaces B: Biointerfaces 182, 110362. https://doi.org/10.1016/j.colsurfb.2019.110362
Kesarwani V., Kelly H.G., Shankar M., Robinson K.J., Kent S.J., Traven A., Corrie S.R. (2019) Characterization of Key Bio-Nano Interactions between Organosilica Nanoparticles and Candida albicans. ACS Applied Materials and Interfaces 11 (38) 34676. https://doi.org/10.1021/acsami.9b10853
Adamus K., Le S.N., Elmlund H., Boudes M., Elmlund D. (2019) AgarFix: Simple and accessible stabilization of challenging single-particle cryo-EM specimens through crosslinking in a matrix of agar. Journal of Structural Biology 207 (3) 327. https://doi.org/10.1016/j.jsb.2019.07.004
King A., Hoch N.C., McGregor N.E., Sims N.A., Smyth I.M., Heierhorst J. (2019) Dynll1 is essential for development and promotes endochondral bone formation by regulating intraflagellar dynein function in primary cilia. Human Molecular Genetics 28 (15) 2573. https://doi.org/10.1093/hmg/ddz083
Lee J.Y., Kim M.J., Thomas S., Oorschot V., Ramm G., Aui P.M., Sekine Y., Deliyanti D., Wilkinson-Berka J., Niego B., Harvey A.R., Theotokis P., McLean C., Strittmatter S.M., Petratos S. (2019) Limiting neuronal nogo receptor 1 signaling during experimental autoimmune encephalomyelitis preserves axonal transport and abrogates inflammatory demyelination. Journal of Neuroscience 39 (28) 5562. https://doi.org/10.1523/JNEUROSCI.1760-18.2019
Gorelick S., Buckley G., Gervinskas G., Johnson T.K., Handley A., Caggiano M.P., Whisstock J.C., Pocock R., de Marco A. (2019) PIE-scope, integrated cryo-correlative light and FIB/SEM microscopy. eLife 8, e45919. https://doi.org/10.7554/eLife.45919
Gargett C.E., Gurung S., Darzi S., Werkmeister J.A., Mukherjee S. (2019) Tissue engineering approaches for treating pelvic organ prolapse using a novel source of stem/stromal cells and new materials. Current Opinion in Urology 29 (4) 450. https://doi.org/10.1097/MOU.0000000000000634
Byrne J.J., Soh M.S., Chandhok G., Vijayaraghavan T., Teoh J.-S., Crawford S., Cobham A.E., Yapa N.M.B., Mirth C.K., Neumann B. (2019) Disruption of mitochondrial dynamics affects behaviour and lifespan in Caenorhabditis elegans. Cellular and Molecular Life Sciences 76 (10) 1967. https://doi.org/10.1007/s00018-019-03024-5
Wood A.J., Cohen N., Joshi V., Li M., Costin A., Hersey L., McKaige E.A., Manneken J.D., Sonntag C., Miles L.B., Siegel A., Currie P.D. (2019) RGD inhibition of itgb1 ameliorates laminin-α2-deficient zebrafish fibre pathology. Human molecular genetics 28 (9) 1403. https://doi.org/10.1093/hmg/ddy426
Ashtiani D., De Marco A., Neild A. (2019) Tailoring surface acoustic wave atomisation for cryo-electron microscopy sample preparation. Lab on a Chip 19 (8) 1378. https://doi.org/10.1039/c8lc01347k
Zhao C., Nguyen N.S., Li X., McCarthy D., Wang H. (2019) Tannic acid coating and in situ deposition of silver nanoparticles to improve the antifouling properties of an ultrafiltration membrane. Journal of Applied Polymer Science 136 (14) 47314. https://doi.org/10.1002/app.47314
Belousoff M.J., Venugopal H., Wright A., Seoner S., Stuart I., Stubenrauch C., Bamert R.S., Lupton D.W., Lithgow T. (2019) cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria. ChemMedChem 14 (5) 527. https://doi.org/10.1002/cmdc.201900042
Sobti M., Ishmukhametov R., Bouwer J.C., Ayer A., Suarna C., Smith N.J., Christie M., Stocker R., Duncan T.M., Stewart A.G. (2019) Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP. eLife 8, e43864. https://doi.org/10.7554/eLife.43864
Zhao C., Lu J., Hou J., Li X., Wang J., Jiang L., Wang H., Zhang H. (2019) Bioinspired Self-Gating Nanofluidic Devices for Autonomous and Periodic Ion Transport and Cargo Release. Advanced Functional Materials 29 (6) 1806416. https://doi.org/10.1002/adfm.201806416
Bakheet B., Beardall J., Zhang X., McCarthy D. (2019) Potential control of cyanobacterial blooms by using a floating-mobile electrochemical system. Journal of Chemical Technology and Biotechnology 94 (2) 582. https://doi.org/10.1002/jctb.5805
Mukherjee S., Darzi S., Rosamilia A., Kadam V., Truong Y., Werkmeister J.A., Gargett C.E. (2019) Blended Nanostructured Degradable Mesh with Endometrial Mesenchymal Stem Cells Promotes Tissue Integration and Anti-Inflammatory Response in Vivo for Pelvic Floor Application. Biomacromolecules 20 (1) 454. https://doi.org/10.1021/acs.biomac.8b01661
Silk M.R., Mohanty B., Sampson J.B., Scanlon M.J., Thompson P.E., Chalmers D.K. (2019) Controlled Construction of Cyclic d / l Peptide Nanorods. Angewandte Chemie - International Edition 58 (2) 596. https://doi.org/10.1002/anie.201811910
Coulibaly F. (2019) Polyhedra, spindles, phage nucleus and pyramids: Structural biology of viral superstructures. Advances in Virus Research 105, 275. https://doi.org/10.1016/bs.aivir.2019.08.001
Suys E.J.A., Warren D.B., Pham A.C., Nowell C.J., Clulow A.J., Benameur H., Porter C.J.H., Pouton C.W., Chalmers D.K. (2019) A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL. Journal of Pharmaceutical Sciences 108 (1) 193. https://doi.org/10.1016/j.xphs.2018.11.028
Bishop D.J., Botella J., Genders A.J., Lee M.J.-C., Saner N.J., Kuang J., Yan X., Granata C. (2019) High-intensity exercise and mitochondrial biogenesis: Current controversies and future research directions. Physiology 34 (1) 56. https://doi.org/10.1152/physiol.00038.2018
Selvadurai M.V., Brazilek R.J., Moon M.J., Rinckel J.-Y., Eckly A., Gachet C., Meikle P.J., Nandurkar H.H., Nesbitt W.S., Hamilton J.R. (2019) The PI 3-kinase PI3KC2α regulates mouse platelet membrane structure and function independently of membrane lipid composition. FEBS Letters 593 (1) 88. https://doi.org/10.1002/1873-3468.13295
T Patton, J-H Jiang, X Kostoulias, V Oorschot, G Ramm, A Peleg, M O'Keeffe (2019) Daptomycin resistance mutations occurring in Staphylococcus aureus impede innate immune recognition by dendritic cells. EUROPEAN JOURNAL OF IMMUNOLOGY 49, 1108. https://doi.org/
Carlie L Cullen, Renee E Pepper, Mackenzie T Clutterbuck, Kimberley A Pitman, Viola Oorschot, Loic Auderset, Alexander D Tang, Georg Ramm, Ben Emery, Jennifer Rodger, Renaud B Jolivet, Kaylene M Young (2019) Myelin and nodal plasticity modulate action potential conduction in the adult mouse brain. bioRxiv 726760. https://doi.org/10.1101/726760
Jing Fu (2019) Building Laboratory-on-Tip for Imaging Biological Samples with Atom Probe Tomography. Microscopy and Microanalysis 25 (s2) 282. https://doi.org/10.1017/S1431927619002149
Shi Qiu, Changxi Zheng, Vivek Garg, Jian Li, Ross KW Marceau, Jing Fu (2019) Mass spectrometry inside single proteins by atom probe tomography. Microscopy and Microanalysis 25 (s2) 334. https://doi.org/10.1017/S143192761900240X
Philipp M Pelz, Robert Bücker, Georg Ramm, Hariprasad Venugopal, Günther Kassier, Dennis Eggert, Peng-Han Lu, Rafal E Dunin-Borkowski, RJ Dwayne Miller (2019) Electron ptychography of single biological macromolecules. Microscopy and Microanalysis 25 (s2) 72. https://doi.org/10.1017/S1431927619001090
Cesare Granata, Vicki Thallas-Bonke, CX Qin, Adrienne Laskowski, Edwina Jap, Georg Ramm, M Cooper, D Stroud, R Ritchie, M Coughlan (2019) SAT-105 GLUCOSE-DEPENDENT MITOCHONDRIAL ALTERATIONS IN DIABETIC KIDNEY DISEASE. Kidney International Reports 4 (7) s50. https://doi.org/10.1016/j.ekir.2019.05.133
Nicole L La Gruta, Kylie M Quinn, Felix Kraus, Luke Formosa, Michael Dagley, Eleanor Saunders, Tabinda Hussain, Lisa Assmus, Adam Costin, Joan Clark, Georg Ramm, Kim Good-Jacobson, Malcolm McConville, Michael Ryan (2019) High Spare Respiratory Capacity is a Canonical Feature of Virtual Memory, but not Conventional Memory CD8 T Cells, and is Driven by IL-15 Signalling. The Journal of Immunology 202 (1_supplement) 60.7. https://doi.org/10.4049/jimmunol.202.Supp.60.7
Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A Spicer, Ruby HP Law, Adrian W Hodel, Sue M Ekkel, Paul J Conroy, Georg Ramm, Hariprasad Venugopal, Phillip I Bird, Bart W Hoogenboom, Ilia Voskoboinik, Yann Gambin, Emma Sierecki, Michelle A Dunstone, James C Whisstock (2019) The structure of Macrophage Expressed Gene-1, a phagolysosome immune effector that is activated upon acidification. bioRxiv 580712. https://doi.org/10.1101/580712
Zhiguang Qiu, Melinda A Coleman, Euan Provost, Alexandra H Campbell, Brendan P Kelaher, Steven J Dalton, Torsten Thomas, Peter D Steinberg, Ezequiel M Marzinelli (2019) Future climate change is predicted to affect the microbiome and condition of habitat-forming kelp. Proceedings of the Royal Society B 286 (1896) 20181887. https://doi.org/10.1098/rspb.2018.1887
Emma Dal Maso, Alisa Glukhova, Yue Zhu, Javier Garcia-Nafria, Christopher G Tate, Silvia Atanasio, Christopher A Reynolds, Erney Ramírez-Aportela, Jose-Maria Carazo, Caroline A Hick, Sebastian GB Furness, Debbie L Hay, Yi-Lynn Liang, Laurence J Miller, Arthur Christopoulos, Ming-Wei Wang, Denise Wootten, Patrick M Sexton (2019) The molecular control of calcitonin receptor signalling. ACS Pharmacology & Translational Science 2 (1) 31. https://doi.org/10.1021/acsptsci.8b00056
Wilson Wong, Rick Huang, Sebastien Menant, Chuan Hong, Jarrod J Sandow, Richard W Birkinshaw, Julie Healer, Anthony N Hodder, Usheer Kanjee, Christopher J Tonkin, Denise Heckmann, Vladislav Soroka, Teit Max Moscote Søgaard, Thomas Jørgensen, Manoj T Duraisingh, Peter E Czabotar, Willem A de Jongh, Wai-Hong Tham, Andrew I Webb, Zhiheng Yu, Alan F Cowman (2019) Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex. Nature 565 (7737) 118. https://doi.org/10.1038/s41586-018-0779-6
-
Spicer B.A., Law R.H.P., Caradoc-Davies T.T., Ekkel S.M., Bayly-Jones C., Pang S.-S., Conroy P.J., Ramm G., Radjainia M., Venugopal H., Whisstock J.C., Dunstone M.A. (2018) The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nature Communications 9 (1) 3266. https://doi.org/10.1038/s41467-018-05717-0
Westhorpe C.L.V., Ursula Norman M., Hall P., Snelgrove S.L., Finsterbusch M., Li A., Lo C., Tan Z.H., Li S., Nilsson S.K., Kitching A.R., Hickey M.J. (2018) Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes. Nature Communications 9 (1) 747. https://doi.org/10.1038/s41467-018-03181-4
Faridi A., Sun Y., Okazaki Y., Peng G., Gao J., Kakinen A., Faridi P., Zhao M., Javed I., Purcell A.W., Davis T.P., Lin S., Oda R., Ding F., Ke P.C. (2018) Mitigating Human IAPP Amyloidogenesis In Vivo with Chiral Silica Nanoribbons. Small 14 (47) 1802825. https://doi.org/10.1002/smll.201802825
Lermusiaux L., Funston A.M. (2018) Plasmonic isomers via DNA-based self-assembly of gold nanoparticles. Nanoscale 10 (41) 19557. https://doi.org/10.1039/c8nr05509b
Lau R.W.K., Wang B., Ricardo S.D. (2018) Gene editing of stem cells for kidney disease modelling and therapeutic intervention. Nephrology 23 (11) 981. https://doi.org/10.1111/nep.13410
Haynes J.M., Selby J.N., Vandekolk T.H., Abad I.P.L., Ho J.K., Lieuw W.-L., Leach K., Savige J., Saini S., Fisher C.L., Ricardo S.D. (2018) Induced pluripotent stem cell-derived podocyte-like cells as models for assessing mechanisms underlying heritable disease phenotype: Initial studies using two alport syndrome patient lines indicate impaired potassium channel activity. Journal of Pharmacology and Experimental Therapeutics 367 (2) 335. https://doi.org/10.1124/jpet.118.250142
Liang Y.-L., Khoshouei M., Deganutti G., Glukhova A., Koole C., Peat T.S., Radjainia M., Plitzko J.M., Baumeister W., Miller L.J., Hay D.L., Christopoulos A., Reynolds C.A., Wootten D., Sexton P.M. (2018) Cryo-EM structure of the active, G s -protein complexed, human CGRP receptor. Nature 561 (7724) 492. https://doi.org/10.1038/s41586-018-0535-y
Liang Y.-L., Zhao P., Draper-Joyce C., Baltos J.-A., Glukhova A., Truong T.T., May L.T., Christopoulos A., Wootten D., Sexton P.M., Furness S.G.B. (2018) Dominant negative g proteins enhance formation and purification of agonist-gpcr-g protein complexes for structure determination. ACS Pharmacology and Translational Science 1 (1) 12. https://doi.org/10.1021/acsptsci.8b00017
McFetridge M.L., Del Borgo M.P., Aguilar M.-I., Ricardo S.D. (2018) The use of hydrogels for cell-based treatment of chronic kidney disease. Clinical Science 132 (17) 1977. https://doi.org/10.1042/CS20180434
Higgins G.C., Nguyen T.-V., Ramm G., Coughlan M.T. (2018) Methods in renal research: Measurement of autophagic flux in the renal cortex ex vivo. Nephrology 23 (9) 815. https://doi.org/10.1111/nep.13251
Garriga D., Headey S., Accurso C., Gunzburg M., Scanlon M., Coulibaly F. (2018) Structural basis for the inhibition of poxvirus assembly by the antibiotic rifampicin. Proceedings of the National Academy of Sciences of the United States of America 115 (33) 8424. https://doi.org/10.1073/pnas.1810398115
Manuguri S., Webster K., Yewdall N.A., An Y., Venugopal H., Bhugra V., Turner A., Domigan L.J., Gerrard J.A., Williams D.E., Malmström J. (2018) Assembly of Protein Stacks with in Situ Synthesized Nanoparticle Cargo. Nano Letters 18 (8) 5138. https://doi.org/10.1021/acs.nanolett.8b02055
Ashtiani D., Venugopal H., Belousoff M., Spicer B., Mak J., Neild A., de Marco A. (2018) Delivery of femtolitre droplets using surface acoustic wave based atomisation for cryo-EM grid preparation. Journal of Structural Biology 203 (2) 94. https://doi.org/10.1016/j.jsb.2018.03.012
Thal D.M., Vuckovic Z., Draper-Joyce C.J., Liang Y.-L., Glukhova A., Christopoulos A., Sexton P.M. (2018) Recent advances in the determination of G protein-coupled receptor structures. Current Opinion in Structural Biology 51, 28. https://doi.org/10.1016/j.sbi.2018.03.002
Shanbhag B.K., Liu C., Haritos V.S., He L. (2018) Understanding the Interplay between Self-Assembling Peptides and Solution Ions for Tunable Protein Nanoparticle Formation. ACS Nano 12 (7) 6956. https://doi.org/10.1021/acsnano.8b02381
Turner L., Bitto N.J., Steer D.L., Lo C., D'Costa K., Ramm G., Shambrook M., Hill A.F., Ferrero R.L., Kaparakis-Liaskos M. (2018) Helicobacter pylori outer membrane vesicle size determines their mechanisms of host cell entry and protein Content. Frontiers in Immunology 9 (1466). https://doi.org/10.3389/fimmu.2018.01466
Malerba M.E., Palacios M.M., Palacios Delgado Y.M., Beardall J., Marshall D.J. (2018) Cell size, photosynthesis and the package effect: an artificial selection approach. New Phytologist 219 (1) 449. https://doi.org/10.1111/nph.15163
Draper-Joyce C.J., Khoshouei M., Thal D.M., Liang Y.-L., Nguyen A.T.N., Furness S.G.B., Venugopal H., Baltos J.-A., Plitzko J.M., Danev R., Baumeister W., May L.T., Wootten D., Sexton P.M., Glukhova A., Christopoulos A. (2018) Structure of the adenosine-bound human adenosine A1 receptor-Gi complex. Nature 558 (7711) 559. https://doi.org/10.1038/s41586-018-0236-6
Sztal T.E., McKaige E.A., Williams C., Oorschot V., Ramm G., Bryson-Richardson R.J. (2018) Testing of therapies in a novel nebulin nemaline myopathy model demonstrate a lack of efficacy. Acta neuropathologica communications 6 (1) 40. https://doi.org/10.1186/s40478-018-0546-9
Selvadurai M.V., Hamilton J.R. (2018) Structure and function of the open canalicular system–the platelet’s specialized internal membrane network. Platelets 29 (4) 319. https://doi.org/10.1080/09537104.2018.1431388
Schneider-Futschik E.K., Paulin O.K.A., Hoyer D., Roberts K.D., Ziogas J., Baker M.A., Karas J., Li J., Velkov T. (2018) Sputum Active Polymyxin Lipopeptides: Activity against Cystic Fibrosis Pseudomonas aeruginosa Isolates and Their Interactions with Sputum Biomolecules. ACS Infectious Diseases 4 (5) 646. https://doi.org/10.1021/acsinfecdis.7b00238
Rabi R., Larcombe S., Mathias R., McGowan S., Awad M., Lyras D. (2018) Clostridium sordellii outer spore proteins maintain spore structural integrity and promote bacterial clearance from the gastrointestinal tract. PLoS Pathogens 14 (4) e1007004. https://doi.org/10.1371/journal.ppat.1007004
Onal E., Frith J.E., Jurg M., Wu X., Molotnikov A. (2018) Mechanical properties and in vitro behavior of additively manufactured and functionally graded Ti6Al4V porous scaffolds. Metals 8 (4) 200. https://doi.org/10.3390/met8040200
Deo P., Chow S.H., Hay I.D., Kleifeld O., Costin A., Elgass K.D., Jiang J.-H., Ramm G., Gabriel K., Dougan G., Lithgow T., Heinz E., Naderer T. (2018) Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis. PLoS Pathogens 14 (3) e1006945. https://doi.org/10.1371/journal.ppat.1006945
Liang Y.-L., Khoshouei M., Glukhova A., Furness S.G.B., Zhao P., Clydesdale L., Koole C., Truong T.T., Thal D.M., Lei S., Radjainia M., Danev R., Baumeister W., Wang M.-W., Miller L.J., Christopoulos A., Sexton P.M., Wootten D. (2018) Phase-plate cryo-EM structure of a biased agonistbound human GLP-1 receptor-Gs complex. Nature 555 (7694) 121. https://doi.org/10.1038/nature25773
Hay I.D., Belousoff M.J., Dunstan R.A., Bamert R.S., Lithgow T. (2018) Structure and membrane topography of the vibrio-type secretin complex from the type 2 secretion system of enteropathogenic Escherichia coli. Journal of Bacteriology 200 (5) e00521-17 https://doi.org/10.1128/JB.00521-17
McArthur K., Whitehead L.W., Heddleston J.M., Li L., Padman B.S., Oorschot V., Geoghegan N.D., Chappaz S., Davidson S., Chin H.S., Lane R.M., Dramicanin M., Saunders T.L., Sugiana C., Lessene R., Osellame L.D., Chew T.-L., Dewson G., Lazarou M., Ramm G., Lessene G., Ryan M.T., Rogers K.L., Van Delft M.F., Kile B.T. (2018) BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis. Science 359 (6378) eaao6047. https://doi.org/10.1126/science.aao6047
Liu Q., Graham B., Hawley A., Dong Y.-D., Boyd B.J. (2018) Novel agrochemical conjugates with self-assembling behaviour. Journal of Colloid and Interface Science 512, 369. https://doi.org/10.1016/j.jcis.2017.10.070
Bakheet B., Islam M.A., Beardall J., Zhang X., McCarthy D. (2018) Electrochemical inactivation of Cylindrospermopsis raciborskii and removal of the cyanotoxin cylindrospermopsin. Journal of Hazardous Materials 344, 241. https://doi.org/10.1016/j.jhazmat.2017.10.024
Wang B., Ji G., Naeem H., Wang J., Kantharidis P., Powell D., Ricardo S.D. (2018) The use of targeted next generation sequencing to explore candidate regulators of TGF-β1's impact on kidney cells. Frontiers in Physiology 9, 1755. https://doi.org/10.3389/fphys.2018.01755
Berger J., Berger S., Li M., Jacoby A.S., Arner A., Bavi N., Stewart A.G., Currie P.D. (2018) In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly. Cell Reports 22 (2) 313. https://doi.org/10.1016/j.celrep.2017.12.069
Reboul C.F., Eager M., Elmlund D., Elmlund H. (2018) Single-particle cryo-EM—Improved ab initio 3D reconstruction with SIMPLE/PRIME. Protein Science 27 (1) 51. https://doi.org/10.1002/pro.3266
Shayanti Mukherjee, Saeedeh Darzi, Anna Rosamilia, Vinod Kadam, Yen Truong, Jerome A Werkmeister, Caroline E Gargett (2018) Blended Nanostructured Degradable Mesh with Endometrial Mesenchymal Stem Cells Promotes Tissue Integration and Anti-Inflammatory Response in Vivo for Pelvic Floor Application. Biomacromolecules 20 (1) 454. https://doi.org/10.1021/acs.biomac.8b01661
Gorelick Sergey, Korneev Denis, Handley Ava, Gervinskas Gediminas, Kaluza Owen L, Law Ruby HP, Bryan Moira O’, Pocock Roger, Whisstock James C, de Marco Alex (2018) Oxygen plasma focused ion beam scanning electron microscopy for biological samples. BioRxiv 457820. https://doi.org/10.1101/457820
Saifei Lei, Lachlan Clydesdale, Antao Dai, Xiaoqing Cai, Yang Feng, Dehua Yang, Yi-Lynn Liang, Cassandra Koole, Peishen Zhao, Thomas Coudrat, Arthur Christopoulos, Ming-Wei Wang, Denise Wootten, Patrick M Sexton (2018) Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism. Journal of Biological Chemistry 293 (24) 9370. https://doi.org/10.1074/jbc.RA118.003278
Bo Wang, Guanyu Ji, Haroon Naeem, Junwen Wang, Phillip Kantharidis, David Powell, Sharon Denise Ricardo (2018) The use of targeted next generation sequencing to determine the regulatory function of TGF-β1 in kidney fibrosis. Frontiers in Physiology 9, 1755. https://doi.org/10.3389/fphys.2018.01755