The mitoHOPE Program clinical trial cannot commence until we are granted the necessary approvals from the relevant human research ethics committees and Australia's Embryo Research Licensing Committee. Our best estimate is that the the clinical trial may commence in the latter half of 2026. However, this could change depending on how quickly the required licences and ethics approvals are granted.

There are several tasks that need to be completed before at-risk individuals can be admitted to the mitoHOPE clinical trial. These tasks include applying for a series of licences that enable the program to commence, training embryologists in the laboratory techniques for mitochondrial donation and ensuring that there is a network of health professionals around Australia ready to support families through the program.

If your family is affected and you think mitochondrial donation may be suitable for you, we suggest you talk to your health professionals while the program is being established. They can help you understand the reproductive options that are most relevant to you.

You can find your local genetics service on the Centre for Genetics Education website. You can also contact the Mito Foundation for information and support.