Meet Monash University’s latest Women in STEMM Student Leaders – Thanh Xuan Le
PhD candidate – Faculty of Medicine, Nursing and Health Sciences
Research focus: Using isothermal amplification assay and microfluidic technologies to develop Point-of-care testing for infectious disease
Thanh-Xuan Le is a recipient of a 2024 Women in STEMM Student Leader Award. These awards aim to recognise, celebrate and support women students at Monash University who are contributing to innovation in healthcare and medical technologies. MIME spoke to Thanh-Xuan upon accepting this award.
What is your chosen degree and what inspired you to pursue this path?
I am currently a PhD candidate in the Neuroscience Department, Faculty of Medicine, Nursing and Health Sciences at Monash University. My passion for rapid diagnostic systems began with my undergraduate thesis, which centred on developing point-of-care testing (POCT) for malaria. Through this work, I recognised the critical need for effective, affordable diagnostic solutions, particularly in low- and middle-income countries and resource-limited settings. Motivated by this impact, I pursued further education to advance this field. My current project aims to develop an integrated system combining microfluidics with isothermal diagnostic assays, with the potential to revolutionise POCT by making it more accessible, accurate, and cost-effective.
What is your favourite aspect about this STEMM field?
My research is highly interdisciplinary, encompassing contributions from diverse fields such as molecular biology, microfluidics, 3D designs and so on. It offers the potential to deliver comprehensive solutions to complex challenges. More importantly, it presents a valuable opportunity for me to develop my skills, broaden my perspective, and collaborate across disciplines.
Can you elaborate on your contribution to innovation in healthcare and medical technologies?
My contribution to innovation in healthcare and medical technologies focuses on rapid diagnostic applications.
During the COVID-19 pandemic, we recognised the critical role of reliable screening tests in managing the spread of the virus and following up after the treatment. My research aims to develop a point-of-care testing (POCT) system that retains the high accuracy of the gold-standard Polymerase Chain Reaction (PCR) method while also offering the affordability, ease of use, and portability of Rapid Antigen Tests (RATs).
To achieve this, my colleagues and I integrated a Loop-Mediated Isothermal Amplification (LAMP) assay with finger-actuated microfluidic devices. This system can self-aspirate the sample and detect viruses in clinical specimens. The results can be easy to read through a colour change from pink to yellow in the positive cases. Notably, using an isothermal assay like LAMP offers high adaptability, making it suitable for detecting various pathogens by targeting their genetic materials.
Can you tell us a little of your leadership experience?
I actively joined the student committee to organise many academic and social events since I was an undergraduate student at my university in Vietnam.
Alongside my PhD studies, I serve as an Event Manager for the School of Translational Medicine Graduate Research Student Committee (STM GRSC), where my team and I organised regular social and academic events for HDR students at STM. Notably, in 2024, we successfully organised the combined Student Symposium and Career Expo on October 3-4, bringing together over 50 HDR students and staff. Additionally, our Career Expo featured esteemed guest speakers for panel discussions and representatives from 13 companies in the STM field.
The MIME Women in STEMM Student Leader Awards recognise student leadership. What does receiving this award mean to you?
It is truly an honour to receive the MIME Women in STEMM Student Leader Award 2024. This recognition holds deep meaning for my effort during my PhD journey. Furthermore, this award presents a wonderful opportunity to connect with talented women in the STEMM field, allowing me to learn from them and be inspired.
What will the $1,000 cash prize to support your studies go towards?
$1000 can be a valuable addition to help me achieve my plans in the final year of my PhD such as attending an abroad conference.
What are you most looking forward to in regard to the MIME networking opportunities afforded to you due to receiving this award?
The MIME networking opportunities will be invaluable for me to connect with other awardees and researchers across various sectors, including industry, academia, and clinical practice. Through these interactions, I hope to gain valuable insights into translational biomedical innovation and its implementation in real-world healthcare settings. Most importantly, I believe that connecting with talented individuals will be a great source of inspiration, motivating me to continue growing in the STEMM field.
Why do you think awards like this are important for Women in STEMM?
This award serves as a recognition for the recipient's efforts on their development journey and an encouragement to continue striving for excellence. Besides, the award is an opportunity to further raise awareness about leadership in STEMM and share positive messages to inspire future generations of women to confidently step into leadership roles and thrive.
What is your advice for women in STEMM or those thinking about a career in STEMM?
We all encounter challenges sometimes but don't rush or fear stepping out of your comfort zone. Follow your passion, keep moving forward, and believe in yourself. Good things take time.