Join our studies

Please note: COVID safe procedures are in place.

All visits can be conducted remotely.



1. METHODS-Extend: An open-label pragmatic trial to determine the efficacy and patient acceptability of methotrexate in hand osteoarthritis

We would like to invite volunteers aged 40–75 years and who suffer from pain and swelling in the joints of the hands to join our clinical trial based at the Musculoskeletal Unit, Monash University, Alfred Hospital, Commercial Road, Prahran.

The METHODS-Extend Study is a one-year open label trial investigating whether the use of methotrexate can be effective in reducing joint damage and pain in people with hand osteoarthritis and joint swelling, and who is more likely to respond to this medication.

As part of the study, participants will undergo screening and monitoring blood tests, a plain chest x-ray and two hand x-rays.

If you are interested in participating or finding out more information about this project, please contact us:

Phone: +61 3 9903 0553

Download Participant Information and Consent Form