Cancer and Blood Diseases
Monash is a research leader in cancer and blood diseases.
Our research covers the spectrum of cancer types, with particular strengths in lung, prostate, breast and colorectal cancers. Leading our work on blood diseases is the Australian Centre for Blood Diseases, which is at the forefront of understanding the process of blood clotting and blood cancers such as acute leukaemia, multiple myeloma and lymphoma.
Work undertaken by the Faculty takes place across multiple schools, institutes, hospitals and partner organisations.
- Hudson Institute – formed as a merger between two of Australia's most trusted names in medical research, Prince Henry's Institute and Monash Institute of Medical Research.
- Monash Comprehensive Cancer Consortium – a research partnership between Monash and its affiliated research institutes.
- Stem Cell Research Group that aims to understand the molecular regulation of normal blood stem cells that are used for bone marrow transplants, and how mutations of our genes can lead to abnormal stem cells
- Myeloma Research Group (MRG) - a partnership between Monash University and Alfred Health that aims to advance therapeutic options for patients with Multiple Myeloma (MM), one of the most common and still incurable blood cancers. The focus of the group is on the translation of pre-clinical studies of novel drug therapies and mechanisms of drug resistance into the design and implementation of clinical trials in MM.
- Haematology and Cancer Research Group in Clinical Sciences at Monash Health integrates research with patient care and is connected to some of Australia’s largest haematological and paediatric leukaemia services.
Cardiovascular diseases are a leading cause of death worldwide. One Australian dies every 11 minutes due to cardiovascular disease and despite rapid and significant improvements over the last few decades, it remains one of the biggest burdens on our economy.
Monash Cardiovascular Research Centre (MCRC) is the formally recognised research arm of MonashHEART, one of the premier clinical cardiac services in Australia. The centre is recognised as being in the top tier internationally in fields including cardiac technology, therapeutic devices and invasive treatment of coronary artery disease; structural and valvular heart disease; establishment of new approaches in the management of cardiac disease; the application of Cardiac CT imaging; and in the investigation of arterial mechanics in the better understanding of cardiovascular pathophysiology.
Critical Care, Trauma and Perioperative Medicine
Together with our research partners, the Faculty has a diverse and comprehensive research program in critical care, trauma and perioperative medicine.
- The National Trauma Research Institute (NTRI) is a department of Monash University and Alfred Health that pursues to minimise injuries and fatalities, and ensure that health care services provide optimal care and rehabilitation following traumatic accident or injury.
- The Department of Anaesthesia and Perioperative Medicine in the Monash Central Clinical School houses a research unit that manages and participates in numerous research trials, funded by a number of large grants.
- The Australian and New Zealand Intensive Care Research Centre (ANZIC-RC) coordinates and conducts comprehensive research programs. It is a bi-national intensive care clinical research methods centre, assisting with the design, funding and execution of clinical trials.
- The Monash Emergency Research Collaborative (MERC) is a multidisciplinary collaborative network of clinical and research focused staff in emergency care that encompasses the three emergency departments of Monash Health.
Development, Stem Cells and Regenerative Medicine
Monash researchers in the field of regenerative medicine are unravelling the basic mechanisms of how tissues repair themselves. Understanding this will enable doctors to prevent, halt and reverse damage to vital organs due to disease, injury or genetic conditions.
Research conducted at the Faculty's Australian Regenerative Medicine Institute (ARMI) and the Department of Anatomy and Developmental Biology contributes to treatments for conditions such as neurodegenerative disorders, musculo-skeletal and cardiovascular diseases.
Infection, Inflammation and Immunity
Infection remains a significant health problem in Australia, and the emergence and spread of drug-resistant pathogens is a cause of great concern globally. Inflammation is implicated in many chronic human disorders including vasculitis, glomerulonephritis, arthritis,
atherosclerosis, lung disease and hepatitis.
Monash researchers are committed to deepening our understanding of immune responses and identifying those that are effective and those that cause inflammation and disease.
The Monash Infection and Immunity Group plays a key role in unravelling the primary causes of infection and immune-related illness. Our research is contributing to new therapies for a wide range of illnesses such as systemic lupus erythematosus, fibrotic disease, influenza, clostridial infections, malaria, babesiosis, Chagas disease and tuberculosis.
Researchers in the Centre for Inflammatory Diseases investigate the roles of inflammation and injury in crippling, and sometimes fatal, human diseases, including lung disease and hepatitis. Bridging the gap between basic experimental biology and clinical research, the Centre's researchers hope to develop novel treatments.
Metabolism, Obesity and Men's Health
Almost two thirds of Australians are overweight or obese, and associated diseases have become a major concern for Monash researchers.
The Monash Obesity and Diabetes Institute (MODI) researchers are searching for medical breakthroughs and drug design to significantly reduce the impacts caused by obesity, diabetes and other metabolic disorders.Male infertility affects one in 20 young Australian men, and can signify the potential for future health problems. Monash administers Andrology Australia, the Australian Centre for Male Reproductive Health, which brings together expertise from across Australia to enhance the reproductive health of males through community and professional education programs and build the evidence base and research capacity in male reproductive health.
Neurosciences and Mental Health
The School of Psychological Sciences has a comprehensive research program, and home to a number of research centres and institutes.
The Monash Alfred Psychiatry Research Centre (MAPrc), one of Australia's largest clinical research centres in psychiatry, conducts world class research to improve the lives of people suffering from serious mental illnesses.
The Monash Institute of Cognitive and Clinical Neurosciences aims to improve the understanding of the human brain through innovative research approaches. It is the largest institute of its kind in Australia and the largest grouping of cognitive and clinical neuroscientists in the Asia-Pacific region.
Our Neuroscience and Neurology Research Group at Monash Health conducts a broad spectrum of research from clinical to laboratory science. Research expertise includes stroke and ageing, movement disorders and epilepsy.
Public Health and Health Systems Improvement
The Faculty's School of Public Health and Preventive Medicine is a leader in the establishment, management and analysis of clinical registries. The importance of registries as a strategy for improving the safety and quality of health care is recognised internationally.
They are increasingly seen as an indispensable tool for measuring access to and appropriateness of care. The School also hosts the Clinical Informatics and Data Management Unit (CIDMU). It is one of the few medical research establishments in Australia with extensive expertise in the management of large databases.
The Insurance Work and Health Group (IWHG) is focused on improving the health of all workers and the sustainability of systems that insure them.
Women's, Children's and Reproductive Health
World class, innovative research into health conditions experienced by women is a major strength within the School of Public Health and Preventive Medicine's Women's Health Research Program and the * Jean Hailes Research Unit. Research in women's health encompasses biological, psychological and social perspectives and is undertaken by several multidisciplinary groups. These groups conduct epidemiological surveys, qualitative studies and randomised controlled trials.
The Department of Paediatrics – including the Ritchie Centre the largest perinatal research centre in Australia – is at the forefront of translational research in paediatrics, from foetal and neonatal health to lung development. It is also home to the Melbourne Children's Sleep Unit.