Dermatology clinical trials

CUTIS partners with the Alfred Dermatology Clinical Trials team to advance new treatments for acute, severe and chronic skin conditions. Together, we undertake investigator-led studies and registries, and connect translational CUTIS projects with Alfred's broader commercial dermatology trial portfolio.

Our trials

This investigator-led, non-interventional study enrols adults with psoriasis and collects blood, DNA swabs and optional skin biopsies to examine antigen presentation in lesional and non-lesional skin. The aim is to identify pathogenic peptides that could support more personalised psoriasis care.
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The Australasian Registry of Severe Cutaneous Adverse Reactions captures clinical, genetic and outcome data on severe drug reactions across Australia and New Zealand. It aims to improve diagnosis, management and prevention, and to identify immune mechanisms and potential treatment targets.
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This non-interventional study examines microbiome, gene-expression and metabolite differences in adults with and without atopic dermatitis. The goal is to identify immune and microbial features linked to eczema and more personalised treatment approaches.
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This placebo-controlled Phase IIb trial evaluates the safety and efficacy of GIA632 in adults with non-segmental vitiligo that has not responded adequately to topical therapy. The study also helps identify the most suitable dose for larger future trials.
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This dose-finding Phase I/II trial evaluates the safety, efficacy and immunogenicity of up to three intramuscular injections of an acne mRNA vaccine in adults aged 18-45 years with moderate to severe acne. The study tests whether the vaccine is safe, effective and able to produce an immune response against acne development.
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This placebo-controlled Phase II trial evaluates the efficacy and safety of brivekimig in adults with moderate to severe hidradenitis suppurativa. Participants receive subcutaneous treatment every two weeks during the placebo-controlled and extension periods.
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This investigator-led study investigates pathophysiological mechanisms in oral lichen planus, a chronic inflammatory mucosal disease. The study is intended to improve understanding of disease mechanisms and support future mechanism-informed treatment approaches.
The Alfred has one of the largest clinical trial portfolios in the country. Find additional dermatology trials through the Alfred clinical trials search.
Find Alfred Heath Dermatology Clinical Trials

Department of Immunology

Medicine, Nursing and Health Sciences

Dermatology clinical trials

Our trials