Qualitative proteomics / shot-gun proteomics

Identifies as many proteins in a sample as possible!

Isolated proteins or even entire proteomes are analyzed by LC-MS/MS. This methodology can be used to (i) identify interaction partners, (ii) verify polymorphisms and other mutations, (iii) analyze secreted proteins, (iv) reveal novel proteomes and (v) confirm the identity of purified proteins, synthesized peptides or gel bands.