Embedded studies

BLENDER

Blend to Limit oxygEN in ECMO: A RanDomised controllEd Registry trial (BLENDER)

A Phase II Multicentre Randomised Controlled Trial

The aim of BLENDER is to determine whether the use of conservative as compared to a liberal oxygen strategy results in improved outcomes for patients receiving VA ECMO.

Study info: monash.edu/medicine/sphpm/anzicrc/research/blender-study

Trial registration: ClinicalTrials.gov ID: NCT03841084

ECMO Card

ECMO Card is a study in patients with COVID-19 who require admission to the intensive care unit, mechanical ventilation and/or ECMO. This study aims to characterise the incidence and clinical features of ICU admission, duration of ECMO, complications and survival of patients.

Study info: elso.org/COVID19/ECMOCARD.aspx

OBLEX

Blood Management During ECMO for Cardiac Support (OBLEX)

OBLEX aims to describe bleeding, thromboembolic complications, blood management and anticoagulation in cardiac ECLS and investigate its associations with morbidity and mortality.

Study info: clinicaltrials.gov/ct2/show/record/NCT03714048

ECMO-Energy

The Measurement of Energy Expenditure in Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation (ECMO)

The aim of the ECMO-Energy study is to assess the feasibility of measuring energy expenditure in critically ill patients receiving VA ECMO.

Study info: monash.edu/medicine/sphpm/anzicrc/research/anzic-rc-nutrition-program/ecmo-energy

Trial registration: Australian New Zealand Clinical Trials Registry (ANZCTR) ID: ACTRN12619000760178

ECMO-Rehab

Early Rehabilitation in Patients on Extracorporeal Membrane Oxygenation (ECMO)

The primary aim of the ECMO rehab study is to evaluate the effects of early rehabilitation on disability in critically ill patients receiving ECMO.

Study info: monash.edu/medicine/sphpm/anzicrc/research/ecmo-rehab

Trial registration: ClinicalTrials.gov ID: NCT05003609