ANZIC-RC Acute Brain Injury Program

The Australian and New Zealand Intensive Care Research Centre Acute Brain Injury Program is led by Andrew Udy. The objectives of the Acute Brain Injury Program are:

  • Foster a coordinated and inter-disciplinary approach to caring for brain injured critically ill patients in Australia and New Zealand
  • Enhance knowledge, education, and training in neurocritical care practice in Australia and New Zealand, and
  • Promote a collaborative research agenda aimed at improving long-term outcomes for brain injured patients.

The Acute Brain Injury Program Research Team includes:

ANZIC-RC Acute Brain Injury Studies - In Progress

Completed Studies

Program Publications in 2023:

  1. Tsigaras ZA, Weeden M, McNamara R, Jeffcote T, Udy AA on behalf of the PRECISION-TBI Investigators. The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management. Critical Care and Resuscitation, 2023; DOI: 10.1016/j.ccrj.2023.10.009.
  2. Picetti E, Bouzat P, Bader MK, Citerio G, Helbok R, Horn J, Macdonald RL, McCredie V, Meyfroidt G, Righy C, Robba C, Sharma D, Smith WS, Suarez JI, Udy A, Wolf S, Taccone FS. A survey on monitoring and and management of cerebral vasospasm and delayed cerebral ischaemia after subarachnoid haemorrhage: The MANTRA Study. Journal of Neurosurgical Anesthesiology, 2023; DOI: 10.1097/ANA0000000000000923.
  3. Betteridge T, Finnis M, Cohen J, Delaney A, Young P, Udy A; PROMOTE-SAH Investigators. Blood pressure management goals in critically ill aneurysmal subarachnoid hemorrhage patients in Australia and New Zealand. Journal of Neurosurgical Anesthesiology, 2023; DOI: 10.1097/ANA.0000000000000926.
  4. Galea I, Bandyopadhyay S, Bulters D, Humar R, Hugelshofer M, Schaer DJ, SAH Delphi Group. Haptoglobin treatment for aneurysmal subarachnoid haemorrhage: Review and expert consensus on clinical translation.  Stroke, 2023; DOI: 10.1161/STROKEAHA.123.040205.
  5. Batchelor P, Bernard S, Gantner D, Udy A, Board J, Fitzgerald M, Skeers P, Battistuzzo C, Stephenson M, Smith K, Nunn A. Immediate cooling and early decompression for the treatment of cervical spinal cord injury: A safety and feasibility study. Therapeutic Hypothermia and Temperature Management, 2023; DOI: 10.1089/ther.2022.0046.
  6. Dixon B, Sharkey JM, Teo EJ, Grace SA, Savage JS, Udy A, Smith P, Hellerstedt J, Santamaria JD. Assessment of non-invasive brain pulse monitor to measure intra-cranial pressure following acute brain injury.  Medical Devices (Auckl), 2023; 16: 15-26. DOI: 10.2147/MDER.S398193
  7. Picetti E, Catena F, Abu-Zidan F, Ansaloni L, Armonda RA, Bala M, Balogh ZJ, Bertuccio A, Biffle WL, Bouzat P, Buki A, Cerasti D, Chestnut RM, Citerio G, Coccolini F, Coimbra R, Coniglio C, Fainardi E, Gupta D, Gurney JM Hawrylux GWJ, Helbok R, Hutchinson PJA, Iaccarino C, Kolias A, Maier RW, Martin MJ, Meyfroidt G, Okonkow DO, Rasulo F, Rizoli S, Rubiano A, Sahuquillo J, Sams VG, Servadei F, Sharma D, Shutter L, Stahel PF, Taccone FS, Udy A, Zoerle T, Agnoletti V, Bravi F, De Sione B, Kluger Y, Marino C, Moore EE, Sartelli M, Weber D, Robba C. Early management of isolated severe traumatic brain injury in patients in a hospital without neurosurgical capabilities: a consensus and clinical recommendations of the World Society of Emergency Surgery (WSES). World Journal of Emergency Surgery, 2023; 18:5, DOI: 10.1186/s13017-022-000468-2.
  8. McNamara R, Meka SA, Anstey J, Fatovich D, Haseler L, Jeffcote T, Udy A, Bellomo R, Fitzgerald M. Development of traumatic brain injury associated intracranial hypertension prediction algorithms: A narrative review.  Journal of Neurotrauma, 2023 40(5-6):416-434, DOI: 10.1089/neu.2022.0201.
  9. Russo G, Harrois A, Anstey J, Van Der Jagt M, Taccone F, Udy A, Citerio G, Duranteau J, Ichai C, Badenes R, Prowle J, Ercole A, Oddo M, Schneider A, Wolf S, Helbok R, Nelson D, Cooper J, for the TBI Collaborative Investigators. Early sedation in traumatic brain injury: a multicentre international observational study. Critical Care and Resuscitation, 2023; 24(4): 319-329.  DOI: 10.51893/2022.4.OA2
  10. Jeffcote T, Weir T, Anstey J, McNamara R, Bellomo R, Udy A. The impact of sedative choice on intracranial and systemic physiology in moderate to severe traumatic brain injury: A scoping Review. Journal of Neurosurgical Anesthesiology, 2023; 35(3): 265-273, DOI: 10.1097/ANA.0000000000000836.
  11. McNamara R, Meka S, Anstey J, Fatovich D, Haseler L, Fitzgerald M, Udy A. The monitoring with advanced sensors, transmission and e-reuscitation in traumatic brain injury (MASTER-TBI) collaborative: Bringing data science to the ICU bedside. Critical Care and Resuscitation, 2023; 24(1): 39-42.  DOI: 10.51893/2022.1.OA5