CCRE Therapeutics undertakes a broad range of research across the basic, clinical and epidemiological fields. In terms of therapeutics, these span the areas from drug target discovery to clinical trials to pharmacoepidemiology and pharmaeconomics. Other strengths of the Centre include clinical quality registries, health promotion and outcomes research generally.

Clinical Research

  • ANBP2: The Second Australian National Blood Pressure Study
  • ASPREE: Placebo Controlled Trial of Low Dose Aspirin in the Elderly
  • AUSPICE: Australian Study for the Prevention through Immunisation of Cardiovascular Events
  • FLOW: Effect of semaglutide versus placebo on the progression of renal impairment in subjects with type 2 diabetes and chronic kidney disease
  • HOPE-3: Heart Outcomes Prevention Evaluation
  • PRECISION: Multi-center, blinded, randomized, PaRallEl-group, Phase 3 study with aproCItentan in Subjects with ResIstant HypertensiON
  • QUARTET: Quadruple UltrA-low-dose tReaTment for hypErTension
  • SCREEN-HF: SCReening Evaluation of the Evolution of New Heart Failure

Program Management

  • ANZSCTS National Database: Australian and New Zealand Society of Cardiac and Thoracic Surgeons
  • MIG: Melbourne Interventional Group
  • VCOR: Victorian Cardiac Outcomes Registry

Pharmacoepidemiology/Translational Research

  • INTEGRATE: An integrated general practice and pharmacy-based intervention to promote the prescription and use of appropriate preventive medications among individuals at high cardiovascular risk