Dr Andre Mu

AMR IMPACT THEME

AMR Evolution and Protective Microbiomes

EXPERTISE

  • Microbial ecology
  • Multi-omics including (meta)genomics, transcriptomics, and untargeted metabolomics
  • Bioinformatics
  • Infectious diseases
  • Geomicrobiology

Andre Mu is a Senior Lecturer and Laboratory Head with the Department of Biochemistry and Molecular Biology at Monash University, and is affiliated with the Biomedicine Discovery Institute’s Infection, and Metabolism, diabetes & obesity Programs.

Andre has over 14 years of training across five world-leading institutions spanning three continents, each position supported by prestigious individual research fellowships, totalling >$411,000, including:

  • Endeavour Research Fellowship at the Doherty Institute (AUS) & University of California San Diego (USA)
  • EMBL-EBI & Sanger Research Fellowship at the Wellcome Sanger Institute & EMBL European Bioinformatics Institute (UK), and
  • NOMIS Foundation Research Fellowship at the Salk Institute for Biological Studies (USA)

Andre had actively sought training with world-leaders in microbiology, microbiome sciences, and host-pathogen interactions, and they are:

  • Prof. Janelle S. Ayres in host metabolism and pathogen interactions (Salk Institute)
  • Prof. Rob Knight in integrative microbiome sciences (UCSD)
  • Dr. Trevor D. Lawley in bacteriophage genomics in early life microbiome sciences (Sanger Institute)
  • Prof. Timothy P. Stinear in pathogen genomics (Unimelb), and
  • Prof. Richard A. Strugnell in molecular microbiology (Unimelb).

His graduate research at the University of Melbourne with Assoc. Prof. John W. Moreau was in environmental sciences elucidating the interactions of a 1.5-km deep subsurface microbial community using high-throughput sequencing technologies. This training underpins Andre’s unique perspectives in understanding the microbial interactions that facilitates the ecological succession of the microbiome following antibiotic exposure.

AMR FOCUS

  • Understanding microbial interactions and metabolic hand-off processes that facilitates colonisation of the gut with antibiotic-resistant pathogens
  • Identifying the microbial host of key metabolites detected in the human gut using integrative bioinformatic approaches on untargeted metabolomics and metagenomics data
  • Understanding host microbiome responses to phage therapy
  • Discovery of novel phage functions to combat AMR