PET-CT (AMREP)

Mediso NanoPET-CT Small Animal Imaging System

The scanner is located at the Alfred Medical Research and Education precinct (AMREP), Commercial Rd Prahran.

pdfInformation sheet for prospective users of the Mediso PET-CT scanner at AMREP

The Mediso NanoPET/CT provides a high-precision gantry for exact alignment of PET/CT data. The gantry bore opening is 16 cm and accommodates imaging of mice, rats and rabbits with interchangeable beds and radiation shields. Mediso's gating package (respiratory & cardiac/ECG) is available for optimal image quality. A complete 360° PET detector ring consisting of 12 modules provides the ultra high resolution and sensitivity, with the reconstructed resolution in the centre of the field of view being less than 1.0 mm.

Image reconstruction is achieved with a fast, iterative and 3D real / post Tera-Tomo™ PET engine using 3D OSEM (Ordered Subset Expectation Maximization) protocols. PET and/or CT scanning can extend up to 300 mm in the axial direction by automated translation of the bed for whole body imaging, with a transaxial range of 45-125 mm. Real time reconstruction of CT data can achieve voxel sizes in the range of 13-37 micron. TM is available for image visualisation, quantification and analysis, including co-registration of PET with CT volumes. Low dose CT protocols (<50 mGy for a 3 minute scan) are compatible with longitudinal rodent studies.

Imaging chambers provide integrated animal support, with gas anaesthesia, controlled heating and probes for intravenous injection.

  • Open access system with a one-step animal loading procedure and single motion PET and CT acquisition to enable automatic fusion of PET and CT images
  • Integrated preclinical animal handling system including plug-in animal beds with remote transfer of gas anesthesia, temperature controlled environment, repeatable positioning of the animal model

Features

  • Low dose CT protocols (<50mGy for a 3 minute scan) are compatible with longitudinal rodent studies.
  • Imaging chambers provide integrated animal support, with gas anaesthesia, controlled heating and probes for intravenous injection.
  • Open access system with a one-step animal loading procedure and singlemotion PET and CT acquisition to enable automatic fusion of PET and CT images
  • Integrated preclinical animal handling system including plug-in animal beds with remote transfer of gas anaesthesia, temperature controlled environment, repeatable positioning of the animal model
  • Second license key of vivoQuant software 2.0 is installed, available and accessible in the PET/CT room

Instrument access protocol

  • Bookings are made via ARIN, as per standard MBI protocol.
  • Users need to liaise with Adrian Quintarelli (Baker IDI OHS General Manager) to obtain keys to the scanner, animal holding and radiopharmacy rooms, and regarding AMREP-specific training/OHS requirements. Please contact Adrian at  adrian.quintarelli@bakeridi.edu.au.
  • Users should note requirement for radiation safety training and individual user radiation licence (Dept of Health) before use of radiopharmaceuticals can commence. See Mediso PET-CT Access Form (AMREP).