Radiochemistry

Gamma counter

Radiochemistry to enable preclinical and clinical studies

MBI’s radiochemistry facilities feature shielded workspaces for automated and manual radiosynthetic work. The facilities are supported by a radioanalytical suite with a range of instruments enabling cutting-edge pre-clinical and translational research.

We can source radioactive tracers, assist with radiopharmaceutical product development, enable preclinical studies and provide advice on designing radiotracers for imaging and radiotherapy.

Preclinical radiochemistry facilities

Mediso PET-CTOur radiochemistry facilities enable small animal nuclear imaging research at our sites in Clayton and Prahran, and large animal simultaneous MR-PET research. They include:

  • a synthesis hot cell;
  • a shielded radiochemistry fume hood;
  • on-site germanium-68/gallium-68 generator;
  • radio-HPLC and radio-TLC analytical instruments;
  • fully automated gamma counter;
  • Twilite automatic blood sampling system
  • access to a range of PET and SPECT radionuclides;
  • access to commercially available radiotracers and radiopharmaceuticals;
  • product development services with experience in labelling of small molecules, peptides and antibodies with a range of radiohalogens and radiometals for imaging and therapy studies;
  • advice in the design of radiotracers for imaging and radiotherapy; and
  • animal holding areas for recovery experiments.

Clinical radiochemistry facilitiesMR-PET scanner

The radiochemistry laboratory provides technical support for contract projects.

For clinical research imaging using our simultaneous MR-PET scanner, our radiopharmacy facilities include:

  • dose calibration of a large range of radiopharmaceuticals for both bolus and infusion administration methods; and
  • the expertise to take venous blood samples before, during and after radiopharmaceutical administration.

Radiochemistry research projects

Read about the Radiochemistry team’s research projects. The team, led by Dr Maggie Aulsebrook, invites collaborations with industry and academia.

Acknowledgement

MBI acknowledges the facilities and scientific and technical assistance of the National Imaging Facility, a National Collaborative Research Infrastructure Strategy (NCRIS) capability, at Monash Biomedical Imaging, Monash University. NIF funded the Radiochemistry laboratory upgrade (in 2022) with support from NCRIS and the Victorian Government (VHESIF).