Ocular Motor Research group
Human Behaviour, Human System Disorders, MRI Techniques, Multiple Sclerosis, Neurocognitive Processes, Neuroimaging, Ocular Motor System.
2019 Fielding-White group. L-R: Ms Elisha Papdemitriou, Ms Paige Foletta, Dr Hue Mun Au Yong, Prof Owen White, Ms Sylvia Dymmock, Ms Georgia Fuller Symons, Ms Emma Solly, A/Prof Joanne White, Dr Meaghan Clough, Dr Wendy Wang.
The group’s research entails an investigation of the ocular motor system as a means of developing an understanding of neurocognitive processes fundamental to normal human behaviour, and how these processes may be, or become, dysfunctional. The work combines a range of sophisticated approaches (ocular motor, neuropsychological and neuroimaging), and primarily explores (dys) function in human lesion and system disorders. Establishing the clinical utility of ocular motor measures is a primary goal of the research, translating research outcomes into clinical practice.
This entails developing and applying methods that can:
- sensitively measure disease severity and evolution
- evaluate the efficacy of treatment
- advance our understanding of the neurobiological bases of phenotypically similar conditions.
- Visual snow causes being revealed
- $140,000 donation kicks off research into Visual Snow
- Visual snow: understanding the neurological condition
Current Project Funding
- 2019 Elucidating the neuropathophysiology of visual snow
Chief Investigators: Fielding, J & White, O.
Funding Source: Visual Snow Initiative
Funding amount; $140,267
- 2017-21 Ocular motor assessment as an extension of the neurological examination in multiple sclerosis
Chief Investigators:Fielding, J
Funding Source:Genzyme Corporation
Funding Amount:$ 668,545
- 2015-19 Correlation of structure and function in the brain in Multiple Sclerosis: is fingolimod neuroprotective?
Chief Investigators: White, O., Fielding, J.
- 2016-20 Correlation of structure and function in multiple sclerosis
Chief Investigators: White, O., Fielding, J. Clough, M.
Funding Source:Cabrini Foundation Clinical Research Grant
Available student research projects
Selected Recent Publications
See recent publications for Jo Fielding in the Monash RSS feed immediately below, at PubMed Fielding J + Monash and select list further down.
- Ternes, A-M., Clough, M, Foletta, P., White, O., & Fielding, J. (2019). Characterisation of inhibitory failure in Multiple Sclerosis: Evidence of impaired conflict resolution. Journal of Clinical and Experimental Neuropsychology, 41(3):320-329.
- Lindor, E., Rinehart, N., & Fielding, J. (2019). Distractor inhibition in autism spectrum disorder: evidence of a selective impairment for individuals with co-occurring motor difficulties. Journal of Autism and Developmental Disorders, 49(2):669-682.
- Lindor, E., Rinehart, N., & Fielding, J. (2018). Superior visual search and crowding abilities are not characteristic of all individuals on the autism spectrum. Journal of Autism and Developmental Disorders, 48(10):3499-3512.
- White, O, McKendrick, A, & Fielding, J. (2018). Visual snow - visual misperception. Journal of Neuro-Ophthalmology, 38(4):514-521.
- Clough, M., Frohman, A., Sears, D., Foletta, P., White, O., & Fielding, J. (2018). Multiple sclerosis: Executive dysfunction, task switching and the role of attention. Multiple Sclerosis Journal: Experimental, Translational and Clinical. 4(2)
- Clough, M., Mutimer, S., Wright, D., Tsang, A., Costello, D., Gardner, A., Stanwell. P., Sun, M., Brady, R., McDonald, S., Webster, K., Johnstone, M., Semple, B., White, O., Frayne, R., Fielding, J., O’Brien, T., & Shultz, S. (2018). Ocular motor, neuropsychological, and multimodal MRI outcomes in amateur Australian rules footballers with a history of sports-related concussion. Journal of Neurotrauma. 35(5):730-738.
- Ginsberg, E., Rinehart, R., & Fielding, J. (2017) Measures of task demand and error analysis in the Corsi block–tapping test. Psychology and Neuroscience. 10(4):404-413
- McKendrick, A., Chan, J., Tien, M., Millist, L., Clough, M., Mack, H., Fielding, J., & White, O. (2017). Behavioural measures of cortical hyperexcitability assessed in people who experience visual snow. Neurology, 88(13):1243-1249.
- Shelton, A., Cornish, K., Clough, M., Gajamange, S., Kolbe, S., & Fielding, J. (2017). Disassociation between brain activation and executive function in Fragile X premutation females, Human Brain Mapping, 38(2):1056-1067
- Shelton, A., Cornish, K., Godler, D., Bui, M., Kolbe, S., & Fielding, J. (2017). White matter microstructure, cognition and molecular markers in Fragile X premutation females. Neurology, 88(22):2080-2088
- Shelton, A., Cornish, K., Kolbe, S., Clough, M., Slater, H.., Xin, L., Kraan, K., Bui, M., Godler, D., & Fielding, J. (2016) Brain structure and intragenic DNA methylation are correlated, and predict executive dysfunction in fragile X premutation females. Translational Psychiatry, 6, e984
- Johnson, B., Lum, J., Rinehart, N. & Fielding, J. (2016). Ocular motor disturbances in autism spectrum disorders: systematic review and comprehensive meta-analysis. Neuroscience & Biobehavioral Reviews, 69:260-79
- Fielding, J., Clough, M., Millist, L., Beh, S., Sears D., Frohman, A., Renneker, R., Lim, J., Lizak, N., Frohman, T., White, O., & Frohman, E. (2015). Ocular motor pathophysiological signatures of cognitive dysfunction in multiple sclerosis. Nature Reviews Neurology, 11, 637–645
- Clough, M., Millist, L., Lizak, N., Frohman, T., Frohman, E., White, O., & Fielding, J. (2015). Ocular motor measures of cognitive dysfunction in Multiple Sclerosis II: Inhibitory control. Journal of Neurology, 262(5):1130-7.
- Clough, M., Mitchell, L., Millist, L., Lizak, N., Frohman, T., Frohman, E., White, O., & Fielding, J. (2015). Ocular motor measures of cognitive dysfunction in Multiple Sclerosis II: Working memory. Journal of Neurology, 262(5):1138-47.