Fielding/White group

Ocular Motor Research group

Key terms

Human Behaviour, Human System Disorders, MRI Techniques, Multiple Sclerosis, Neurocognitive Processes, Neuroimaging, Ocular Motor System.

The group

2019 Fielding-White group. L-R: Ms Elisha Papdemitriou, Ms Paige Foletta, Dr Hue Mun Au Yong, Prof Owen White, Ms Sylvia Dymmock, Ms Georgia Fuller Symons, Ms Emma Solly, A/Prof Joanne White, Dr Meaghan Clough, Dr Wendy Wang.

Group Leaders

A/Prof Joanne Fielding

Prof Owen White

The group's research entails an investigation of the ocular motor system as a means of developing an understanding of neurocognitive processes fundamental to normal human behaviour, and how these processes may be, or become, dysfunctional.

Research Overview

The group’s research entails an investigation of the ocular motor system as a means of developing an understanding of neurocognitive processes fundamental to normal human behaviour, and how these processes may be, or become, dysfunctional. The work combines a range of sophisticated approaches (ocular motor, neuropsychological and neuroimaging), and primarily explores (dys) function in human lesion and system disorders. Establishing the clinical utility of ocular motor measures is a primary goal of the research, translating research outcomes into clinical practice.

This entails developing and applying methods that can:

• sensitively measure disease severity and evolution
• evaluate the efficacy of treatment
• advance our understanding of the neurobiological bases of phenotypically similar conditions.

News updates

• Idiopathic Intracranial Hypertension
  • Plain language summary
• Visual snow causes being revealed
  • Plain language summary
  • Video
• $140,000 donation kicks off research into Visual Snow
• Visual snow: understanding the neurological condition

Projects

Current Project Funding

• 2019 Elucidating the neuropathophysiology of visual snow
  Chief Investigators: Fielding, J & White, O.
  Funding Source: Visual Snow Initiative
  Funding amount; $140,267
• 2017-21 Ocular motor assessment as an extension of the neurological examination in multiple sclerosis
  Chief Investigators:Fielding, J
  Funding Source:Genzyme Corporation
  Funding Amount:$ 668,545
• 2015-19 Correlation of structure and function in the brain in Multiple Sclerosis: is fingolimod neuroprotective?
  Chief Investigators:  White, O., Fielding, J.
  Funding Source:Novartis
  Funding Amount:$476,722
• 2016-20 Correlation of structure and function in multiple sclerosis
  Chief Investigators:  White, O., Fielding, J. Clough, M.
  Funding Source:Cabrini Foundation Clinical Research Grant
  Funding Amount:$29,830.00

Available student research projects

• Motor proficiency and attentional control in Autism spectrum disorder

Selected Recent Publications

See recent publications for Jo Fielding in the Monash RSS feed immediately below, at PubMed Fielding J + Monash and select list further down.

• Ternes, A-M., Clough, M, Foletta, P., White, O., & Fielding, J. (2019). Characterisation of inhibitory failure in Multiple Sclerosis: Evidence of impaired conflict resolution. Journal of Clinical and Experimental Neuropsychology, 41(3):320-329.
• Lindor, E., Rinehart, N., & Fielding, J. (2019). Distractor inhibition in autism spectrum disorder: evidence of a selective impairment for individuals with co-occurring motor difficulties. Journal of Autism and Developmental Disorders, 49(2):669-682.
• Lindor, E., Rinehart, N., & Fielding, J. (2018). Superior visual search and crowding abilities are not characteristic of all individuals on the autism spectrum. Journal of Autism and Developmental Disorders, 48(10):3499-3512.
• White, O, McKendrick, A, & Fielding, J. (2018). Visual snow - visual misperception. Journal of Neuro-Ophthalmology, 38(4):514-521.
• Clough, M., Frohman, A., Sears, D., Foletta, P., White, O., & Fielding, J. (2018). Multiple sclerosis: Executive dysfunction, task switching and the role of attention. Multiple Sclerosis Journal: Experimental, Translational and Clinical. 4(2)
• Clough, M., Mutimer, S., Wright, D., Tsang, A., Costello, D., Gardner, A., Stanwell. P., Sun, M., Brady, R., McDonald, S., Webster, K., Johnstone, M., Semple, B., White, O., Frayne, R., Fielding, J., O’Brien, T., & Shultz, S. (2018). Ocular motor, neuropsychological, and multimodal MRI outcomes in amateur Australian rules footballers with a history of sports-related concussion. Journal of Neurotrauma. 35(5):730-738.
• Ginsberg, E., Rinehart, R., & Fielding, J. (2017) Measures of task demand and error analysis in the Corsi block–tapping test. Psychology and Neuroscience. 10(4):404-413
• McKendrick, A., Chan, J., Tien, M., Millist, L., Clough, M., Mack, H., Fielding, J., & White, O. (2017). Behavioural measures of cortical hyperexcitability assessed in people who experience visual snow. Neurology, 88(13):1243-1249.
• Shelton, A., Cornish, K., Clough, M., Gajamange, S., Kolbe, S., & Fielding, J. (2017). Disassociation between brain activation and executive function in Fragile X premutation females, Human Brain Mapping, 38(2):1056-1067
• Shelton, A., Cornish, K., Godler, D., Bui, M., Kolbe, S., & Fielding, J. (2017). White matter microstructure, cognition and molecular markers in Fragile X premutation females. Neurology, 88(22):2080-2088
• Shelton, A., Cornish, K., Kolbe, S., Clough, M., Slater, H.., Xin, L., Kraan, K., Bui, M., Godler, D., & Fielding, J. (2016) Brain structure and intragenic DNA methylation are correlated, and predict executive dysfunction in fragile X premutation females. Translational Psychiatry, 6, e984
• Johnson, B., Lum, J., Rinehart, N. & Fielding, J. (2016). Ocular motor disturbances in autism spectrum disorders: systematic review and comprehensive meta-analysis. Neuroscience & Biobehavioral Reviews, 69:260-79
• Fielding, J., Clough, M., Millist, L., Beh, S., Sears D., Frohman, A., Renneker, R., Lim, J., Lizak, N., Frohman, T., White, O., & Frohman, E. (2015). Ocular motor pathophysiological signatures of cognitive dysfunction in multiple sclerosis. Nature Reviews Neurology, 11, 637–645
• Clough, M., Millist, L., Lizak, N., Frohman, T., Frohman, E., White, O., & Fielding, J. (2015). Ocular motor measures of cognitive dysfunction in Multiple Sclerosis II: Inhibitory control. Journal of Neurology, 262(5):1130-7.
• Clough, M., Mitchell, L., Millist, L., Lizak, N., Frohman, T., Frohman, E., White, O., & Fielding, J. (2015). Ocular motor measures of cognitive dysfunction in Multiple Sclerosis II: Working memory. Journal of Neurology, 262(5):1138-47.