Thermobifida fusca: the manure-dwelling 'hot bug' that may result in life-saving antibiotics

Dr Thierry Izoré, an ECR from the Cryle lab.
Dr Thierry Izoré, an ECR from the Cryle lab.

Dr Thierry Izoré, an ECR from the Cryle lab, has featured in an article in Lens about the bacteria Thermobifida fusca. This 'hot bug' grows in temperatures around 55-60 degrees Celsius and could help to build last-line antibiotics. Because of its painfully slow speed of growth, Dr Izoré is using an Escherichia coli lab strain to express crucial enzymes from this tiny thermophile and figure out how to make non-ribosomal peptide synthetase, which can be used to make crucial antibiotics.