What we do

Our program was founded to help researchers access, understand and use the myriad computational tools available for AI-guided protein design, bringing them to the Australian research ecosystem where they can accelerate research and innovation. Working with the AIPDP provides access to a platform capability in AI-accelerated protein design for use by academic researchers and industry to develop therapeutics, diagnostics, and research tools.

Our team leverages combinations of validated publicly available software (RFDiffusion, ProteinMPNN, BindCraft, etc) and custom networks to provide local researchers with the benefit of the best tools for their task. For example, we recently reported the application of RFDiffusion and ProteinMPNN to unconditionally design inhibitors of soluble bacterial enzymes (Taveneau et al., 2024) and bacterial membrane proteins (Fox et al., 2024).

Our expert team of structural biologists and computer scientists understand the design process from end-to-end. This in-depth knowledge of protein structure and machine learning makes us a highly agile program capable of regularly onboarding cutting edge tools in AI-protein design. We work with users, taking the time to address specific project needs with customized state-of-the-art computational technologies, empowering and upskilling the broader research workforce to create unique solutions to challenges in biology and protein design.