Stem cells show potential for asthma treatment

Associate Professor Crishan Samuel and Dr Simon Royce
Associate Professor Crishan Samuel and Dr Simon Royce

Monash BDI scientists have demonstrated that a new therapy, developed through stem cell technology, holds promise as a treatment for chronic asthma. The research, led by Associate Professor Chrishan Samuel and Dr Simon Royce, was published in the journal FASEB and received press coverage in LabOnline. The researcher's tested the efficacy of Cynata Therapeutics' induced pluripotent stem cell derived mesenchymal stem cells (MSCs) in a pre-clinical model of experimental asthma, and found MSCs could effectively reduce inflammation, reversed signs of airway remodeling and completely normalised airway/lung fibrosis and airway hyperresponsiveness, particularly when delivered intranasally.

Read the press release.