Jörg Group

Chemical probes and small molecules for drug discovery

We are a medicinal chemistry lab focusing on the development of novel chemicals probes. The molecules we design support studies to improve our understanding of proteins on a molecular level, and to address important questions in molecular biology related to the structure, activation, degradation, oligomerisation, allostery and selectivity of selected drug targets. By developing first-in-class chemical probes of therapeutically relevant proteins, we will get pivotal insights into the action of drugs, drug targets and diseases that will enable the development of improved therapeutics and diagnostics.