Watson Group

Engineering biomolecules for precision therapeutics

Our research uses synthetic organic chemistry to combine and functionalise biomolecules (peptides, proteins, nucleic acids) and their mimics in inventive ways to create controllable therapeutic agents. We have a particular focus on developing and applying cutting-edge synthetic protein methodologies to assemble and decorate these complex biomolecules. We also use designer mimics of nucleic acids in combination with proteins to create smart, responsive systems which can release or activate therapeutic agents specifically at disease sites for improved safety and toxicity profiles.