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Lockie Laboratory

Appetite & Behavioural
Control Group

Welcome to the Lockie Lab

We study how hunger signalling in the brain drives mood-related behaviour, memory, motivation and metabolism in mouse models of disease.

We're part of the Monash Biomedicine Discovery Institute, and a member of the Metabolism, Diabetes & Obesity,
Neuroscience and Cancer Programs, and the Department of Physiology.

Dr Sarah Lockie

My global research connections, partners and funding can be viewed on my Monash Research Profile.

If you are a student interested in doing research in our lab, visit Supervisor Connect.

Click the links below to connect with me on Twitter, ORCID, Google Scholar and LinkedIn.

Our research

People with very high, or very low, body weights are much more likely to suffer depression and anxiety-related mental illness. From animal studies, we know that the brain circuits that control feeding and metabolism also play a role in mood, motivation, stress resilience and cognitive function. We use complex mouse genetic models in the presence of cancer cachexia, obesity and chronic calorie restriction to investigate how these systems work normally, and how they fail in complex disease states.

Lab members

We are committed to excellence in research.


View our chosen highlighted key publications.

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We want to share our research discoveries & successes with you.

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Join Our Lab

We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.

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