Surgical Ongology (Peter MacCallum Cancer Centre)

About Surgical Ongology (Peter MacCallum Cancer Centre) Research

A Randomised Phase III Study and Advanced Oesophageal Cancer to Compare Quality of Life and Palliation of Dysphagia in Patients Treated with Radiotherapy versus Chemo-Radiotherapy. A Prospective Study to Evaluate the Impact of PET on Radiotherapy Treatment Planning for Oesophageal Cancer. A Phase II Study of Gemcitabine Integrated with Concomitant 5FU and 3-D Conformal Radiotherapy for the Treatment of Localised Pancreatic Cancer. These are just some of the research topics our team are working on to help improve the outcomes of surgical ongology.

Unit head

Dr Sam Ngan
+61 3 9656 1726

Surgical Oncology research projects

There is potential for undergraduate or postgraduate students to be involved in these studies.

A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum (TROG 0104)
This is an inter-group trial with trans-Tasman Radiation Oncology Group, Australasian Gastro-intestinal Trials Group, Colorectal Surgical Society of Australasia, and Section of Colon and Rectal Surgery, Royal Australasian College of surgeons. It is a trial comparing short and long course of preoperative radiotherapy for rectal cancer. (Financially supported by NHMRC, Cancer Council Victoria, and RANZCR research grants).
A Randomised Phase III Study and Advanced Oesophageal Cancer to Compare Quality of Life and Palliation of Dysphagia in Patients Treated with Radiotherapy versus Chemo-Radiotherapy (TROG 0301)
This is an intergroup study with Trans Tasman Radiation Oncology Group and National Cancer Institute of Cancer Clinical Trials Group to compare palliative radiotherapy alone and chemo radiation. (Financially supported by NHMRC, Cancer Council NSW and Tasmania research grants).
A Phase I Trial of Reload, Gemcitabine and Radiation in the Treatment of Pancreatic Cancer
Phase I/II Trial of Docetaxel, Cisplatin and Concurrent Radiotherapy in Locally Advanced Oesophageal Cancer
- A Phase II Study of Gemcitabine Integrated with Concomitant 5FU and 3-D Conformal Radiotherapy for the Treatment of Localised Pancreatic Cancer
  - This is a national trial for the Australasian Pancreatic Cancer Study Group to study 3-D conformal radiotherapy for pancreatic cancer.
- Preoperative Radiotherapy with Protacted Infusion 5-Fluorouracil for Resectable Adenocarcinoma of Rectum (TROG 9801)
  - This is an Australian and New Zealand trial for Trans-Tasman Radiation Oncology Group to investigate preoperative chemoradiation for rectal cancer.
- A Phase I Study Of Xeloda Combined with Radiotherapy for Locally Advanced, Potentially Operable Rectal Cancer
  - This is a multicentre trial to study a novel approach of Xeloda (capecitabine) combining with preoperative radiotherapy for rectal cancer.
- A Phase I Trial of Preoperative Radiotherapy Combined with Infusional 5-Fluorouracil and Oxaliplatin for Patients with Unresectable Rectal Cancer
  - This is a multicentre trial to study a novel approach of oxaliplatin combining with radiotherapy for advanced rectal cancer.
- A Prospective Single Arm Study of Intraoperative Radiotherapy (IORT) for Locally Advanced or Recurrent Rectal Cancer
- A Phase II Trial of Radiotherapy with Protracted Infusion 5FU and Bolus Mitomycin C for Localised Squamous Cell Carcinoma of Anus
- A Prospective Study to Evaluate the Impact of PET on Radiotherapy Treatment Planning for Oesophageal Cancer
- Phase I/II Trial of Celecoxib (Celebrex®) with Chemotherapy and Radiotherapy in the Treatment of Advanced Oesophageal Cancer

Clinical Sciences at Monash Health

Medicine, Nursing and Health Sciences

Surgical Ongology (Peter MacCallum Cancer Centre)

About Surgical Ongology (Peter MacCallum Cancer Centre) Research

Surgical Oncology research projects