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Big Data, Epidemiology and Prevention Division

Our division comprises experienced health service researchers, epidemiologists, biostatisticians, clinicians and health information managers. We have core skills and expertise in the linkage, curation and analytics of big data for stroke research; surveillance of indicators of stroke burden (i.e. risk factors, incidence, quality of care, stroke documentation and coding); and improving the prevention of stroke and cardiovascular diseases through high-quality observational studies and clinical trials.

Head

Prof Monique Kilkenny (PhD, MPH, Grad Epi & Biostat, B Sci MRA) is the Head of Division with the Stroke and Ageing Research Group. Prof Kilkenny is a highly experienced epidemiologist who collaborates with other national and international researchers in the field of stroke using linked data for performance monitoring, quality improvement research and health promotion evaluations.

Find out more about Prof Monique Kilkenny

Meet the team View

Research groups and publications

Our group oversee the National Stroke Data Linkage Program, which includes >23 million linked health records for participants in the Australian Stroke Clinical Registry. A number of projects have been undertaken to examine the continuum of stroke care using linked data on ambulance attendances, emergency presentations, admissions, medication claims, doctor visits, rehabilitation services, aged care, general practice visits and deaths. Prof Kilkenny co-leads the National Stroke Data Linkage Interest Group.

Big data
Selected relevant publications
- Kilkenny MF, Kim J, Andrew NE, Sundarararjan V, Thrift AG, Katzenellenbogen J, Flack F, Gattellari M, Boyd JH, Anderson P, Lannin NA, Sipthorp M, Chen Y, Johnston T, Anderson CS, Middleton S, Donnan G, Cadilhac DA. Maximising use of data and avoiding data waste: a validation study in stroke research. Med J Aust. 2019;210(1):27-31 doi.org/10.5694/mja2.12029
- Ung D, Dalli LL, Lopez D, Sanfilippo F, Kim J, Andrew NE, Thrift AG, Cadilhac DA, Anderson CS, Kilkenny MF. Assuming one dose per day yields a similar estimate of medication adherence in patients with stroke: an exploratory analysis using linked registry data. Br J Clin Pharmacol. 2021 Mar;87(3):1089-97 doi.org/10.1111/bcp.14468
- Ung D, Kim J, Thrift AG, Cadilhac DA, Andrew N, Sundararajan V, Kapral M, Reeves M, Kilkenny M. The Promising Use of 'Big Data' to Increase the Efficiency and Comprehensiveness of Stroke Outcomes Research. Stroke 2019:50(5):1302-1309 doi.org/10.1161/STROKEAHA.118.020372
- Dalli LL, Kilkenny MF, Arnet I, Sanfilippo FM, Cummings DM, Kapral MK, Kim J, Cameron J, Yap KY, Greenland M, Cadilhac DA. Towards better reporting of the Proportion of Days Covered method in cardiovascular medication adherence: A scoping review and new tool TEN-SPIDERS. Br J Clin Pharmacol. 2022 May 6 doi.org/10.1111/bcp.15391
- Olaiya MT, Sodhi-Berry N, Dalli LL, Bam K, Thrift AG, Katzenellenbogen JM, Nedkoff L, Kim J, Kilkenny MF. The Allure of Big Data to Improve Stroke Outcomes: Review of Current Literature. Curr. Neurol. Neurosci. Rep. 2022;22:151-160 doi.org/10.1007/s11910-022-01180-z
Our team specialise in epidemiology (including pharmacoepidemiology) and oversee the analyses and reporting of data from the Stroke Foundation Audit Program and the Australian Stroke Clinical Registry. Members also contribute to the regular reporting of the Global Stroke Statistics in the International Journal of Stroke. Monitoring of stroke is important and our group are at the forefront to improve stroke coding to ensure accurate and reliable data. Prof Kilkenny established and leads the Australia and New Zealand Stroke Coding Working Group.

Epidemiology
Selected relevant publications
- Ryan OF, Riley M, Cadilhac DA, Andrew NA, Breen S, Paice K, Shehata S, Sundararajan V, Lannin N, Kim J, Kilkenny MF. Factors Associated with Stroke Coding Quality: A Comparison of Registry and Administrative Data. J Stroke Cerebrovasc Dis. 2021;30(2):105469. doi.org/10.1016/j.jstrokecerebrovasdis.2020.105469
- Kilkenny MF, Phan HT, Lindley RI, Kim J, Lopez D, Dalli LL, Grimley R, Sundararajan V, Thrift AG, Andrew NE, Donnan GA, Cadilhac DA. Utility of the Hospital Frailty Risk Score Derived from Administrative Data and the Association with Stroke Outcomes Stroke. 2021;52(9):2874-2881. doi.org/10.1161/strokeaha.120.03364
- Dalli LL, Kim J, Thrift AG, Andrew NE, Sanfilippo FM, Lopez D, Grimley R, Lannin NA, Wong L, Lindley RI, Campbell BCV, Anderson CS, Cadilhac DA, Kilkenny MF. Patterns of use and discontinuation of secondary prevention medications after stroke. Neurology. 2021: 96 (1): e30-e41 doi.org/10.1212/WNL.0000000000011083
- Kilkenny MF, Dalli LL, Kim J, Sundararajan V, Andrew NE, Dewey HM, Johnston T, Alif S, Lindley RI, Jude M, Blacker D, Gange N, Grimley R, Katzenellenbogen JM, Thrift AG, Lannin NA, Cadilhac DA, On behalf of the Stroke123 investigators and AuSCR Consortium. Factors associated with 90-day readmission after stroke/TIA using linked observational Australian Stroke Registry data. Stroke, 2020;51(2):571-578 doi.org/10.1161/STROKEAHA.119.026133
Our team co-lead the Love Your Brain project (Medical Research Future Fund #2015976) with researchers from the University of Tasmania and partnering with the Stroke Foundation. Many Australians experience stroke. There is huge public demand for information about how to stop stroke, which can be met by our “Love Your Brain” digital platform. The platform comprises an online course and messaging system on risk factor management, leveraging an existing Stroke Foundation program. We will test the effectiveness of this platform for helping more people in the community identify and manage their risk factors. This platform aims to reduce the incidence of stroke.
Selected relevant publications
- Bam K, Olaiya M, Cadilhac DA, Donnan G, Murphy L, Kilkenny MK. Enhancing primary stroke prevention using the combination approach. The Lancet Public Health 2022;7(8):e721-e724. doi.org/10.1016/S2468-2667(22)00156-6.
- Kilkenny, MF, Purvis T, Werner M, Reyneke M, Czerenkowski J, Cadilhac DA. Improving stroke knowledge and health behaviours through a “volunteer led” community education program in Australia. Preventive Medicine 2016;86:1-5 doi.org/10.1016/j.ypmed.2016.01.015.
- Cadilhac D, Kilkenny M, Johnson R, Wilkinson B, Amatya B, Lalor E. The Know your numbers (KYN) Program 2008 to 2010: impact on knowledge and health promotion behaviour among participants. International Journal Stroke 2015; 10(1):110-6 doi.org/10.1111/ijs.12018
- Kilkenny M, Johnson R, Cadilhac D. Feasibility of a pilot program to increase awareness of blood pressure as an important risk factor for stroke in Australia. International Journal Stroke 2010; 5(5):344-50 doi.org/10.1111/j.1747-4949.2010.00456.x

Clinical Sciences at Monash Health

Medicine, Nursing and Health Sciences

Big Data, Epidemiology and Prevention Division

Head

Meet the team View

Meet the team

Researchers

Research groups and publications

Selected relevant publications

Selected relevant publications

Selected relevant publications