Inflammatory Respiratory Disease Research Group
About the Inflammatory Respiratory Disease Research Group
Chronic Obstructive Lung Disease (COPD) is the fourth major killer worldwide. Smoking and pollution are major factors. Smoking damaged lungs are susceptible to chronic bacterial invasion and inflammation leading to loss of lung and formation of scars (emphysema and bronchitis). We have shown Haemophilus is the major bacterial pathogen in COPD and that sufferers have abnormal and inefficient immune responses. Defining the molecular basis of these defective immune responses has provided opportunities to enhance immunity and reduce the injurious inflammation.
The outcome in respiratory infection is primarily determined by the interaction between the bacterial pathogen and host immune response. We have a longstanding research interest in assessing the immune response to common bacteria. Our work has concentrated on clinical samples from patients and cell lines.
Ms Lovisa Dousha
Read and access our key publications.