Upper Gastrointestinal Surgery

About the Upper Gastrointestinal and Hepatobiliary Research Unit

Relief of symptoms following cholecystectomy. Quality and value of lymphadenectomy in gastric cancer resection. Management of nausea after upper G.I. surgery. Management strategies for postoperative infection in G.I. surgery. This is just a taste of the kinds of research investigations being undertaken by the Upper Gastrointestinal and Hepatobiliary Unit.

Gastrointestinal research projects

  • The effect of Intraoperative cholangiography on post operative LFTs – a randomized trail. Ethics approval obtained. Not recruiting yet.
  • An audit of bile culture result from bile obtained at major HPB resections – on going.
  • The MORPh trial. Monash Outpatients Review by Phone. A prospective trial. Completed. Presented as poster at ASC 2016. Manuscript in preparation.
  • The effect of patient position on ERCP – a randomized trial. Run in conjunction with the Gastroenterology department. Recruiting.
  • A review of the accuracy of EUS FNA in pancreatic tumours: comparing adenocarcinoma to neuroendocrine malignancy. Data obtained. Manuscript in preparation.
  • The natural history of autoimmune pancreatitis. Description of a cohort at Monash Medical Centre. On Going.
  • Review of staging prior to oesophagectomy  -  The Australian Experience. About to commence. Abandoned as Medicare would not provide data
  • The effect of the introduction of the Acute Surgical Unit on the treatment of patients with acute cholecystitis and biliary colic. Complete and published
  • The expression of STAT3,  IL6 and IL11 in patients with pancreatic cancer. Ongoing.
  • Victorian Pancreatic Cancer Biobank. Ethics approval. Awaiting governance approval at other sites around Melbourne
  • Examination of the effect of EGFR inhibitors on KRAS wildtype pancreatic cancer in a patient derived xenograft model
  • Examination of the genomic differences between KRAS wildtype and mutant pancreatic cancer
  • The role of body composition in surgical conditions of the gastrointestinal tract. On going