Stephen Opat

Prof Stephen Opat is Director of Clinical Haematology at Monash Health and Head of Department of Haematology, School of Clinical Sciences at Monash Health, Monash University.

Prof Opat’s research aims to improve outcomes for patients with lymphoma and chronic lymphocytic leukaemia, and to achieve these ends he has employed a number of strategies.

The Lymphoma and Related Diseases Registry (housed within Monash University’s, Department of Epidemiology and Preventive Medicine) enables haematologists across Australia and New Zealand to monitor access to care; benchmark outcomes nationally and internationally; explore variation in practice; and act as a resource for clinical trials.

As Director of the Monash Haematology Clinical Research Unit, Prof Opat has also been principal investigator in over 40 studies in lymphoma and chronic lymphocytic leukaemia.  The Unit is engaged in all aspects of clinical research, from first in human to large international phase III studies.

Another research interest of Prof Opat’s is improving the understanding of lymphoma biology to facilitate the rational application of targeted therapy.

The Melbourne Genomics Health Alliance Lymphoma flagship is a collaborative effort to improve outcomes for patients with poor-risk non-Hodgkins lymphoma through gaining an understanding of the genetic lesions involved in the malignant transformation of lymphoid cells.  The project involves genetic sequencing of tumour DNA coding regions to identify genetic variants that may help guide treatment.

Find out more about Prof Stephen Opat.