A/Professor Shaun Gregory

A/Professor Shaun Gregory

Adjunct / Honorary Professor
Director, Centre for Biomedical Technologies, Queensland University of Technology
Department of Mechanical and Aerospace Engineering
Queensland University of Technology

A/Prof Gregory has completed Bachelor, Master and PhD degrees in medical engineering at Queensland University of Technology. He then completed his postdoctoral years at the University of Queensland and Griffith University where he was the Innovative Cardiovascular Engineering and Technology Laboratory (ICETLAB) Director for five years and the Chief Technical Officer for De Motu Cordis Pty Ltd (a medication delivery company) for 3 years. A/Prof Gregory is now the Deputy Head of Department for Mechanical and Aerospace Engineering, the Director of the CardioRespiratory Engineering and Technology Laboratory, Co-Director of the Artificial Heart Frontiers Program, and Academic Director and Founder of the Heart Hackathon international student team competition. He currently holds fellowships with the NHMRC and Heart Foundation of Australia (Future Leader Fellow). A/Prof Gregory’s research focuses on cardiovascular engineering, with a particular interest in the development and evaluation of devices for mechanical circulatory and respiratory support. This is achieved through A/Prof Gregory’s multidisciplinary research group incorporating different types of engineering (e.g. mechanical, electrical, materials, and more), biomedical science, IT, design and medicine.

Qualifications

  • Doctor of Philosophy,(Ph,D), BioMedical/ Medical Engineering , QUT (Queensland University of Technology)
  • Master's Degree, BioMedical/ Medical Engineering , QUT (Queensland University of Technology)
  • Bachelor's Degree, BioMedical/ Medical Engineering , QUT (Queensland University of Technology)

Current Appointments

Director, Centre for Biomedical Technologies, Queensland University of Technology

Adjunct Senior Lecturer. School of Engineering, Griffith University, Queensland, Australia.

Honorary Fellow. Royal Brisbane Clinical School, The University of Queensland, Brisbane, Queensland, Australia.

Previous Appointments

2018-2024: Associate Professor. Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, Victoria, Australia.

2013-2015: Postdoctoral Research Fellow. Faculty of Health Sciences, School of Medicine, The University of Queensland, Brisbane, Queensland, Australia.

2013-2017: Technical Director. Innovative Cardiovascular Engineering and Technology Laboratory, The Prince Charles Hospital, Brisbane, Queensland, Australia.

2013-2017: Principal Research Fellow – Biomedical Engineering. Critical Care Research Group, The Prince Charles Hospital, Brisbane, Queensland, Australia.

2014-2017: Chief Technical Officer. De Motu Cordis Pty Ltd, Brisbane, Queensland, Australia.

2016-2017: Research Fellow. School of Engineering, Griffith University, Queensland, Australia.

 

 

Research Interests

Dr. Gregory has completed Bachelor, Masters and PhD degrees in medical engineering at Queensland University of Technology (QUT). He then completed his three year postdoctoral fellowship at the University of Queensland’s (UQ) School of Medicine which was followed by a two year research fellowship in Griffith University’s School of Engineering. During both of these fellowships, Dr Gregory was based at The Prince Charles Hospital (TPCH), where he was the Technical Director of the Innovative Cardiovascular Engineering and Research Laboratory (ICETLAB) and a Principal Research Fellow (Engineering) for the Critical Care Research Group. Dr Gregory joined the Department of Mechanical and Aerospace Engineering at Monash University in 2018, and is also a member of the Monash Institute of Medical Engineering.

Dr Gregory’s primary research focus is on the development and evaluation of cardiovascular devices, with a particular focus on rotary blood pumps. He has expertise in areas including anatomical fitting, cannula design, mock circulation loop development, physiological control, in-vitro and in-vivo evaluation of cardiovascular devices, and more. He also has some industry experience, with a three-year role as Chief Technology Officer for De Motu Cordis Pty Ltd, a medication delivery company. Some of his ongoing research projects include:

– Development of a mechanical representation of the heart and circulatory system for laboratory testing of cardiovascular devices

– Design and evaluation of a new surgical fixation mechanism for implanting mechanical circulatory and respiratory support

– Physiological control systems which automatically adjust mechanical circulatory and respiratory support performance based on patient requirements

– Improving the end-user experience by incorporating all user (patient, caregiver, doctor, etc) requirements for mechanical circulatory and respiratory support

Peer Reviewed Publications

 

Gregory, S., Timms, D., Pearcy, M.J., Tansley, G., A naturally shaped silicone ventricle evaluated in a mock circulation loop – A preliminary study. Journal of Medical Engineering and Technology. 2009. 33(3); p185-191.

Gregory, S.D., Greatrex, N., Timms, D., Gaddum, N., Pearcy, M.J., Fraser, J.F., Simulation and enhancement of a cardiovascular device test rig. Journal of Simulation, 2010.4: p. 34-41.

Laumen, M., Kaufmann, T., Timms, D., Schlanstein, P., Jansen, S., Wong, K.C., Gregory, S., Moritz, A., Schmitz-Rode, T., Steinseifer, U., Flow analysis of VAD inflow and outflow cannula positioning using a naturally shaped ventricle and aortic branch. Artificial Organs, 2010.34(10): p. 798-806.

Timms, D., Gregory, S., Hsu, P.L., Thomson, B., Pearcy, M.J., McNeil, K., Fraser, J.F., Steinseifer, U., Atrial vs ventricular cannulation for a rotary VAD. Artificial Organs, 2010.34(9): p. 714-720.

Timms, D., Gregory, S.D., Greatrex, N., Pearcy, M.J., Fraser, J.F., Steinseifer, U., A compact mock circulation loop for the in-vitro testing of cardiovascular devices. Artificial Organs, 2011.35: p. 384-91.

Gregory, S.D., Timms, D., Gaddum, N., Mason, D.G. and Fraser, J.F., Biventricular assist devices: A technical review. Annals of Biomedical Engineering, 2011.39(9): p. 2313-2328.

Gregory, S.D., Timms, D., Gaddum, N.R., McDonald, C., Pearcy, M.J. and Fraser, J.F., In-Vitro Evaluation of a Compliant Inflow Cannula Reservoir to Reduce Suck-Down Events with Extracorporeal, Rotary VAD Support. Artificial Organs, 2011.35(8): p. 765-772.

Gregory, S.D., Stevens, M., Timms, D., Pearcy, M. Replication of the Frank-Starling response in a mock circulation loop. Conf Proc IEEE Eng Med Biol Soc. 2011: 6825-8.

Timms, D., Gregory, S.D., Stevens, M., Fraser, J.F. Hemodynamic modelling of the cardiovascular system using mock circulation loops to test cardiovascular devices. Conf Proc IEEE Eng Med Biol Soc. 2011: 4301-4.

Gregory, S.D., Pearcy, M., Timms, D., Passive control of a biventricular assist device with compliant inflow cannulae. Artificial Organs, 2012. 36(8): p. 683-90.

Salamonsen, R.F., Lim, E., Gaddum, N., Alomari, A.H., Gregory, S.D., Stevens, M., Mason, D.G., Fraser, J.F., Timms, D., Karunanithi, M.K., Lovell, N.H., Theoretical foundations of a Starling-like controller for rotary blood pumps. Artificial Organs, 2012.36(9): p. 787-796.

Gregory, S.D., Loechel, N., Pearcy, M.J., Fraser, J.F., Parnis, S., Cohn, W.E., Timms, D. Anatomic fitting of total artificial hearts for in-vivo evaluation. Artificial Organs, 2013. 37(8): p. 735-741.

Gregory, S.D., Pearcy, M.J., Fraser, J.F., Timms, D., Evaluation of inflow cannulation site for implantation of right sided rotary ventricular assist device. Artificial Organs, 2013.37(8): p. 704-711. 20 th December 2017 

Gregory, S.D., Stevens, M.C., Wu, E., Fraser, J.F., Timms, D., In-vitro evaluation of aortic insufficiency with a rotary left ventricular assist device. Artificial Organs, 2013. 37(9): p. 802-809.

Chemonges, S., Tung, J.P., Dunster, K.R., Diab, S., Watts, R., Gregory, S.D., Foley, S., Platts, D., Toon, M., Shekar, K., Maybauer, M.O., Fraser, J.F. Optimal management of the critically ill: A review of anaesthesia, monitoring, data capture and point-of- care technological practices in ovine models of critical care. BioMed Research International. 2014. doi:10.1155/2014/468309.

Stevens, M., Gregory, S.D., Nestler, F., Thomson, B., Choudhary, J., Garlick, B., Pauls, J.P., Fraser, J.F., Timms, D. In-vitro and in-vivo characterization of three different modes of pump operation when using an LVAD as an RVAD. Artificial Organs. 2014. 38(11): p. 931-9. doi:10.1111/aor.12289

Kaufmann, T.A.S., Gregory, S.D., Buesen, M., Tansley, G.D., Steinseifer U. Development of a numerical Pump Testing Framework (nPTF). Artificial Organs. 2014. 38(9): p. 783-790.

Pauls, J. P., Gregory, S.D., Stevens, M., Tansley, G. In-vitro evaluation of physiological controller response of rotary blood pumps to changes in patient state. Conf Proc IEEE Eng Med Biol Soc. 2014. doi: 10.1109/EMBC.2014.6943587.

Gregory, S.D., Schummy, E., Pearcy, M., Pauls, J.P., Tansley, G., Fraser, J.F., Timms, D. A compliant, banded outflow cannula for decreased after-load sensitivity of rotary right ventricular assist devices. Artificial Organs. 2015. 39(2): p. 102-109. doi:10.1111/aor.12338.

Lo, C., Gregory, S.D., Stevens, M., Murphy, D., Marasco, S. Banding the right ventricular assist device outflow conduit: is it really necessary with current devices? Artificial Organs. 2015. Doi: 10.1111/aor.12497.

Gregory, S.D., Cooney, H., Diab, S., Anstey, C., Thom, O., Fraser, J.F. In-vitro evaluation of an ultrasonic cardiac output monitoring device. Journal of Clinical Monitoring and Computing. 2016. Doi:10.1007/s10877-015- 9685-8.

McDonald, C.I., Bolle, E., Lang, H.F., Ribolzi, C., Thomson, B., Tansley, G.D., Fraser, J.F., Gregory, S.D. Hydrodynamic evaluation of aortic cardiopulmonary bypass cannulae using particle image velocimetry. Perfusion. 2016. Doi: 10.1177/0267659115586282.

Nadeem, K., Ng, B.C., Lim, E., Gregory, S.D., Salamonsen, R.F., Stevens, M.C., Mubin, M., Lovell, N. Numerical Simulation of biventricular assist device with constant pulmonary banding resistance during pulmonary hypertension. Annals of Biomedical Engineering. 2016. Doi: 10.1007/s10439-015-1388-2.

Pauls, J.P., Stevens, M., Schummy, E., Tansley, G., Fraser, J., Timms, D., Gregory, S.D. In-vitro comparison of active and passive physiological control systems for biventricular assist devices. Annals of Biomedical Engineering. 2016. 44(5): 1370-1380. Doi: 10.1007/s10439-015- 1425-1.

Gregory, S.D., Stevens, M.C., Pauls, J.P., Schummy, E., Diab, S., Thomson, B., Anderson, B., Tansley, Salamonsen, R., G., Fraser, J.F., Timms, D. In-vivo evaluation of active and passive physiological 20 th December 2017

control systems for rotary left and right ventricular assist devices. Artificial Organs. 2016. 40(9): 894-Doi: 10.1111/aor.12654.

Pauls, J.P., Stevens, M.C., Bartnikowski, N., Fraser, J.F., Gregory, S.D., Tansley, G. Evaluation of physiological control systems for rotary left ventricular assist devices – an in-vitro study. Annals of Biomedical Engineering. 2016. Doi: 10.1007/s10439-016- 1552-3.

Shekar, K., Gregory, S., Fraser, J. Mechanical circulatory support in the new era: an overview. Critical Care. 2016. Doi: 10.1186/s13054-016- 1235-3. Gregory, S.D., Stevens, M.C., Wu, E.L., Pauls, J.P., Kleinheyer, M., Fraser, J.F. Mitral valve regurgitation with a rotary left ventricular assist device – the haemodynamic effect of inlet cannulation site and speed modulation. Annals of Biomedical Engineering. 2016. 44(9), 2674-2682. Doi: 10.1007/s10439-016- 1579-5.

Liao, S., Langfield, B., Ristovski, N., Hardt, J., Blackwood, K., Yambem, S., Gregory, S.D., Woodruff, M., Powell, S. Effect of humidity on melt electrospun polycaprolactone scaffolds. BioNanoMaterials. 2016. 17(3-4): 173-178.

Liao, S., Simpson, B., Neidlin, M., Kaufmann, T.A.S., Li, Z., Woodruff, M.A., Gregory, S.D. Numerical prediction of thrombus risk in an anatomically dilated left ventricle: The effect of inflow cannula designs. BioMedical Engineering Online. 2016. Doi: 10.1186/s12938-016- 0262-2.

Mansouri, M., Gregory, S.D., Salamonsen, R.F., Lovell, N.H., Stevens, M.C., Pauls, J.P., Akmeliawati,R., Lim, E. Preload-based Starling-like control of rotary blood pumps: An in-vitro validation. PLOS ONE. 2017. 12(2): e0172393. doi:10.1371/journal.pone.0172393. McKenzie, S.C., Dunster, K., Chan, W., Brown, M.R., Platts, D.G., Javorsky, G., Anstey, C., Gregory,S.D. Reliability of thermodilution derived cardiac output with different operator characteristics. Journal of Clinical Monitoring and Computing. 2017. Doi: 10.1007/s10877-017- 0010-6.

Pauls, J.P., Nandakumar, D., Horobin, J., Simmonds, M.J., Fraser, J.F., Tansley, G., Gregory, S.D. The effect of compliant inflow cannulae on the haemocompatibility of rotary blood pump circuits in an in-vitro model. Artificial Organs. 2017. Doi: 10.1111/aor.12919.

Stephens, A.F., Stevens, M.C., Gregory, S.D., Kleinheyer, M., Salamonsen, R.F. Starling-like control of dual ventricular assist devices; Proof of concept I, the immediate response. Artificial Organs. 2017. Doi: 10.1111/aor.12962.

Wu, E.L., Nestler, F., Kleinheyer, M., Stevens, M.C., Pauls, J.P., Fraser, J.F., Gregory, S.D. Pulmonary valve opening with two rotary left ventricular assist devices for biventricular support. Artificial Organs. 2017. Doi: 10.1111/aor.12967.

Platts, D., Loechel, N., Gregory, S.D., Scalia, G., Fraser, J. Impact of a continuous flow ventricularassist device on contrast microspheres – an in-vitro evaluation using a mock circulation loop. BioMed Research International. 2017. Doi: 10.1155/2017/4907898 20 th December 2017

Ng, BC., Salamonsen, R.F., Gregory, S.D., Stevens, M.C., Wu, Y., Mansouri, M., Lovell, N.H., Lim, E. Application of multiobjective neural predictive control to biventricular assistance using dual rotaryblood pumps. Computers in Biology and Medicine. 2018. 39: 81-93.

Liao, S., Theodoropoulos, C., Blackwood, K., Woodruff, M.A., Gregory, S.D. Melt electrospun bilayered scaffolds for tissue integration of a suture-less cannula for rotary blood pumps. Artificial Organs. 2017. Doi 10.1111/aor.13018.

Jayathurathnage, P.K.S., Vilathgamuwa, M., Gregory, S.D., Fraser, J.F. Tran, N.T. Effects of adjacent transmitter current for multi-transmitter wireless power transfer. IEEE SPEC. IN PRESS (Accepted 19/09/2017).

Pauls, J.P., Roberts, L.A., Burgess, T., Fraser, J.F., Gregory, S.D., Tansley, G. Time course response of the healthy heart and circulatory system to active postural changes. Journal of Biomechanical Engineering. IN PRESS (Accepted 11/10/2017).

Liao, S., Neidlin, M., Li, Z., Simpson, B., Gregory, S.D. Ventricular flow dynamics with varying LVAD inflow cannula length: in-silico evaluation in a multiscale model. Journal of Biomechanics. Submitted (23/08/2017).

Wu, E.L., Stevens, M.C., Nestler, F., Bradley, A.P., Tansley, G., Fraser, J.F., Gregory, S.D. A Starling-like physiological controller for rotary blood pumps based on estimated left ventricular stroke work – an in-vitro evaluation. Annals of Biomedical Engineering. Submitted (27/10/2017).

Book Chapters

Shekar, K., Gregory, S.D., Fraser, J.F. Mechanical Circulatory Support in the New Era: An Overview. Annual Update in Intensive Care and Emergency Medicine. 2016. Pages 195-215.

Gregory, S.D., Nadeem, K., Chiang, B. Biventricular Assist Devices. Mechanical Circulatory and Respiratory Support. 2017. Pages 187-218. ISBN 978-0- 12-810491- 0.

Gregory, S.D., Zwischenberger, J., Wang, D., Liao, S., Slaughter, M. Cannula Design. Mechanical Circulatory and Respiratory Support. 2017. Pages 567-596. ISBN 978-0- 12-810491- 0.

Millar, J.E., Gregory, S.D., Stevens, M.C., Fraser, J.F., Bartlett, B. The future of mechanical circulatory and respiratory support. Mechanical Circulatory and Respiratory Support. 2017. Pages 777-800. ISBN 978-0- 12-810491- 0.

Books

Gregory, S.D., Stevens, M.S., Fraser, J.F. Mechanical Circulatory and Respiratory Support. Elsevier. 2017. 858 pages. ISBN 978-0- 12-810491- 0. 20 th December 2017

Conference Presentations

Gregory, S., Timms, D., Tansley, G. and Pearcy, M.J. Evaluation of VAD cannula inflow using a naturally shaped silicone ventricle. International Society for Rotary Blood Pumps. 2007. Sydney, Australia: Poster presentation

Gregory, S., Timms, D., Fraser, J. F. and Pearcy, M. J. Development of a compact mock cardiovascular system for educational purposes. National Heart Foundation Conference. 2009. Brisbane, Australia, Poster presentation.

Gregory, S., Wong, K. C., Timms, D., Laumen, M., Jansen, S., Tansley, G. and Pearcy, M. J. Evaluation of VAD cannula inflow using a naturally shaped silicone ventricle in a mock circulation loop. National Heart Foundation Conference. 2009. Brisbane, Australia, Poster presentation.

Timms, D., Fraser, J. F., Thomson, B., Greatrex, N., Gregory, S. and McNeil, K. BiVACOR – Toward a totally implantable artificial heart. National Heart Foundation Conference. 2009. Brisbane, Australia, Poster presentation.

Gregory, S., Timms, D., Greatrex, N., Fraser, J.F. and Pearcy, M.J. VAD inflow cannula evaluation in a mock circulation loop. International Society for Rotary Blood Pumps 2009. Singapore: Poster Presentation.

Gregory, S. D., Timms, D., Gaddum, N., Pearcy, M. J. and Fraser, J. F. In-Vitro Evaluation of a Compliant Inflow Cannula Reservoir to Reduce Suck-Down Events with Extracorporeal, Rotary VAD Support. International Society for Rotary Blood Pumps. 2010. Berlin, Germany.

Gregory, S.D., Timms, D., Pearcy, M., Fraser, J.F. Placement of a compliant inflow for passive control of rotary biventricular assist devices. The Prince Charles Hospital Foundation Conference. October 31. 2011. Brisbane, Australia: Oral Presentation.

Gregory, S.D., Timms, D., Pearcy, M. and Fraser, J.F. Passive Control of a Biventricular Assist Device with Compliant Inflow Cannulae. International Society for Rotary Blood Pumps. September 8-10. 2011. Louisville, KY, USA: Oral Presentation

Gregory, S.D., Timms, D., Loechel, N., Yuen, A., Thomson, B. and Fraser, J.F. A total artificial heart anatomical fitting tool for chronic animal trials. International Society for Rotary Blood Pumps. September 8-10. 2011. Louisville, Kentucky, USA: Poster Presentation

Gregory, S.D., Timms, D., Pearcy, M. and Fraser, J.F. Right Heart Inflow Cannula Placement for Rotary Biventricular Assistance. International Society for Rotary Blood Pumps. September 8-10. 2011. Louisville, Kentucky, USA: Poster Presentation

Gregory, S.D., Stevens, M., Timms, D., Pearcy, M. Replication of the Frank-Starling response in a mock circulation loop. IEEE Engineering in Medicine and Biology Society. August 30 – September 3. 2011. Boston, Massachusetts, USA: Oral Presentation. 20 th December 2017

Gregory, S.D., Timms, D., Pearcy, M. Passive control of a biventricular assist device with compliant cannulae. Australian Biomedical Engineering Conference. September 16-18. 2012. Brisbane, Australia: Oral Presentation.

Gregory, S.D., Timms, D., Leibhardt, A., Pearcy, M. A cannulation system to reduce apical bleeding and passively adapt rotary blood pump outflow. International Society for Rotary Blood Pumps. September 18-20. 2012. Istanbul, Turkey: Poster Presentation.

Gregory, S.D., Stevens, M., Timms, D. Can changing LVAD speed accommodate for aortic insufficiency? Characterizing the effect of mild, moderate and severe AI in a variable heart failure model. International Society for Rotary Blood Pumps. September 18-20. 2012. Istanbul, Turkey: Poster Presentation.

Gregory, S.D., Moser, K., Yuen, A., Timms, D., Tansley, G., Fraser, J.F. Speed modulation of rotary blood pumps – characterising the effects of speed waveform, amplitude, and phase delay with varying degrees of heart failure. International Society for Rotary Blood Pumps. September 26-29. 2013. Yokohama, Japan: Oral Presentation.

Gregory, S.D., Moser, K., Yuen, A., Timms, D., Tansley, G., Fraser, J.F. Speed modulation of rotary blood pumps – the haemodynamic benefits of simulating a pulse. The Prince Charles Hospital Foundation Conference. October 17-18. 2013. Brisbane, Australia: Oral Presentation.

Gregory, S.D., Stevens, M.C., Pauls, J.P., Schummy, E., Thomson, B., Choudhary, J., Diab, S., Tansley G., Fraser, J.F., Timms, D. In-vivo evaluation of passive and active control systems for rotary left and right ventricular assist devices. International Society for Rotary Blood Pumps. September 25-27.2014. San Francisco, USA: Oral Presentation.

Gregory, S.D., Lang, H.F., Ribolzi, C., Timms, D., Tansley G., Fraser, J.F. The effect of inflow cannula geometry on left ventricular flow dynamics – an in-vitro study. International Society for Rotary Blood Pumps. September 25-27. 2014. San Francisco, USA: Poster Presentation.

Gregory, S.D., Stevens, M.C., Pauls, J.P., Schummy, E., Thomson, B., Choudhary, J., Diab, S., Tansley G., Fraser, J.F., Timms, D. In-vivo evaluation of flow control strategies for mechanical circulatory support. The Prince Charles Hospital Foundation Conference. October 30-31. 2014. Brisbane, Australia: Oral Presentation.

Gregory, S.D., Chan, W., Platts, D., Javorsky, G., Anstey, C., McKenzie, S. Reliability of thermodilution derived cardiac output with different operator characteristics. The Prince Charles Hospital Foundation Conference. November 5-6. 2015. Brisbane, Australia: Oral Presentation.

Gregory, S.D., Stephens, A., Bartnikowski, N., Anstey, C., Fraser, J.F., McGiffin, D., Salamonsen, R. In- vitro evaluation of the HeartWare HVAD flow estimator for LVAD and RVAD applications.International Society for Rotary Blood Pumps. September 20-22. 2016. Mito, Japan: Poster and Rapid-Fire Oral Presentation. 20 th December 2017 

Gregory, S.D. Machines That Keep the Heart Beating. The Prince Charles Hospital Research Forum. October 17-21. 2016. Brisbane, Australia. Invited Oral Presentation.

Gregory, S.D. Improving the patient-device interface of cardio-respiratory mechanical assist devices. Centre for Research Excellence Conference. 28-29 November. 2016. Sydney, Australia. Invited Oral Presentation.

Gregory, S.D. Innovative Cardiovascular Engineering and Technology Laboratory. Centre for Research Excellence Conference. 28-29 November. 2016. Sydney, Australia. Invited Oral Presentation.

Gregory, S.D. Pauls, J.P., Stephens, A., Wu, E., Kleinheyer, M., Stevens, M., Tansley, G. An advanced mock circulation loop for in-vitro evaluation of cardiovascular devices. Gordon Research Seminar on Assisted Circulation. June 24-25. 2017. Stowe, Vermont, USA: Oral Presentation.

Gregory, S.D. Smart pump control – What has been done, how to optimize, and what are the open questions. Gordon Research Conference on Assisted Circulation. June 25-30. 2017. Stowe, Vermont, USA: Invited Oral Presentation.

Gregory, S.D. It’s not just a pump – a focus on the MCS system. Asia-Pacific Extracorporeal Life Support Organisation Conference. October 12-14. 2017. Gold Coast, Australia. Invited Oral Presentation.

Gregory, S.D. Growing an investigative and translational career. International Society for Mechanical Circulatory Support. October 16-18. Tuscon, AZ, USA. Invited Oral Presentation. 20 th December 2017

Invited Lectures

Gregory, S.D. Heart disease and cardiovascular devices. Queensland University of Technology Biofluids Guest Lecture. 2009. Brisbane, Australia.

Gregory, S.D. Artificial Heart Research Grants. The Prince Charles Hospital Foundation Board Meeting – Research Summary. 2010. Brisbane, Australia.

Gregory, S.D. Heart disease and cardiovascular devices. Queensland University of Technology Biofluids Guest Lecture. 2010. Brisbane, Australia.

Gregory, S.D. Innovative cardiovascular engineering and technology (ICET) Laboratory Overview. The Prince Charles Hospital Research Meeting. 2011. Brisbane, Australia.

Gregory, S.D. Research summary for the Innovative Cardiovascular Engineering and Technology Laboratory. ICETLab Annual Reporting Meeting. 2011. Brisbane, Australia.

Gregory, S.D. Emerging cardiovascular devices and technology. Queensland University of Technology medical device domain meeting. 2011. Brisbane, Australia.

Gregory, S.D. Heart disease and cardiovascular devices. Queensland University of Technology Biofluids Guest Lecture. 2011. Brisbane, Australia.

Gregory, S.D. Research summary for the Innovative Cardiovascular Engineering and Technology Laboratory. ICETLab Annual Reporting Meeting. 2012. Brisbane, Australia.

Gregory, S.D. Heart disease and cardiovascular devices. Queensland University of Technology Biofluids Guest Lecture. 2012. Brisbane, Australia.

Gregory, S.D. Research summary for BiVACOR and the Innovative Cardiovascular Engineering and Technology Laboratory. Baulderstone fundraising event. 2013. Brisbane, Australia.

Gregory, S.D. Research summary for the Innovative Cardiovascular Engineering and Technology Laboratory. Critical Care Research Group Annual Reporting Meeting. 2013. Brisbane, Australia.

Gregory, S.D. Research overview for the Innovative Cardiovascular Engineering and Technology Laboratory. Grand Rounds, The Prince Charles Hospital. 2013. Brisbane, Australia.

Gregory, S.D. Engineering – More than just transport and mining. Griffith University engineering opportunities seminar. 2013. Gold Coast, Australia.

Gregory, S.D. Innovative Cardiovascular Engineering and Technology Laboratory Update. International Collaborative Research Update. 2013. Ibaraki, Japan.

Gregory, S.D. Research summary for the Innovative Cardiovascular Engineering and Technology Laboratory. ICETLab Annual Reporting Meeting. 2013. Brisbane, Australia. 20 th December 2017 

Gregory, S.D. Heart disease and cardiovascular devices. Queensland University of Technology Biofluids Guest Lecture. 2013. Brisbane, Australia.

Gregory, S.D. Medical Engineering Research. Queensland University of Technology medical engineers careers night. 2013. Brisbane, Australia.

Gregory, S.D. Research summary for BiVACOR and the Innovative Cardiovascular Engineering and Technology Laboratory. St John of Jerusalem fundraising event. 2013. Brisbane, Australia.

Gregory, S.D. Research grants and opportunities. The Prince Charles Hospital Foundation Forum. 2014. Brisbane, Australia.

Gregory, S.D. Causes of, and solutions to, heart failure. Queensland University of Technology Biofluids Guest Lecture. 2014. Brisbane, Australia.

Gregory, S.D. The innovative cardiovascular engineering and technology laboratory – A summary of research. The Critical Care Research Group Forum. 2014. Brisbane, Australia.

Gregory, S.D. Interplay between clinicians and engineers. Princess Alexandra Cardiac Research Symposium. 2015. Brisbane, Australia.

Gregory, S.D. In-vivo evaluation of mechanical circulatory support. MERF Research Day. 2015. Brisbane, Australia.

Gregory, S.D. Innovative Cardiovascular Engineering and Technology Laboratory Update. Cardiac Research Seminar with the Australian College of Critical Care Nurses. 2015. Brisbane, Australia.

Gregory, S.D. Heart Disease and Cardiovascular Devices. Queensland University of Technology Biofluids Guest Lecture. 2015. Brisbane, Australia.

Gregory, S.D. Heart Disease and Cardiovascular Devices. Queensland University of Technology Biofluids Guest Lecture. 2016. Brisbane, Australia.

Gregory, S.D. Supporting Medical Research. The Prince Charles Hospital Fundraising Event. 2016. Brisbane, Australia.

Gregory, S.D. Medical engineering research careers. Queensland University of Technology Fellowship of Medical Engineers Event. 2016. Brisbane, Australia.

Gregory, S.D. Replacing the heart with a mechanical pump – cardiovascular engineering in the ICETLAB. Monash University Guest Lecture. 2017. Melbourne, Australia.

Gregory, S.D. Heart Disease and Cardiovascular Devices. Queensland University of Technology Biofluids Guest Lecture. 2017. Brisbane, Australia. 20 th December 2017 

Gregory, S.D. Life after a PhD – A research and industry perspective. Queensland University of Technology Careers Day. 2017. Brisbane, Australia.

Gregory, S.D. Post-HDR options. The University of Queensland Faculty of Medicine HDR Day. 2017. Brisbane, Australia.

Gregory, S.D. Cardiovascular engineering in the ICETLAB – How to replace the heart with a mechanical pump. Redcliffe Hospital Grand Rounds. 2017. Redcliffe, Australia.

Gregory, S.D. Replacing the heart with a mechanical pump – Cardiovascular engineering in the ICETLAB. University of New South Wales seminar. 2017. Sydney, Australia.

 

Grants

Fraser, J.F., Timms, D., McNeil, K., Pearcy, M., McDonald, C., Dunning, J., Galbraith, A., Gregory, S.,Practical Simulation of the Human Cardiovascular System for Education and Training (S08/002).Australian and New Zealand College of Anaesthetists. 2008. $21,650.

Timms, D., Fraser, J.F., Pearcy, M., Gregory, S., Design and evaluation of new cannulae for bi- ventricular assist devices (FRC0208-16). The Prince Charles Hospital Foundation. 2008. $25,500.

Gregory, S., Travel Grant (TG09B4735). National Heart Foundation. 2009. $2,000.

Gregory, S., Fraser, J.F., Optimization of the VAD-patient interface to improve rotary and pulsatile VAD efficiency and reduce the occurrence of ventricular suck-down events (NR2010-116). The Prince Charles Hospital Foundation. 2010. $9,700.

Gregory, S., Small equipment grant: Flow sensor (SEQ2010-07). The Prince Charles Hospital Foundation. 2010. $3,910.

Gregory, S., Small equipment grant: Power supply and data transfer assembly (SEQ2011-08). The Prince Charles Hospital Foundation. 2011. $4,581.90.

Gregory, S., Large equipment grant: Flow meter and accessories (LEQ2011-07). The Prince Charles Hospital Foundation. 2011. $19,000.

Gregory, S., Travel Grant. Medical Advances Without Animals (MAWA). 2011. $2,000.

Gregory, S., Large equipment grant: Rapid prototyper and accessories (LEQ2012-05). The Prince Charles Hospital Foundation. 2012. $18,000.

Timms, D., Gregory, S.D., Stevens, M., Fraser, J.F., Pearcy, M.J., Improving the preload and afterload sensitivity of rotary ventricular assist devices through the combination of passive and active control systems. (MS2012-34). The Prince Charles Hospital Foundation. 2012. $71,087.

Gregory, S., Small equipment grant: Perivascular flow probe and accessories (SEQ2013-07). The Prince Charles Hospital Foundation. 2013. $3,920.00

Fraser, J.F., Karunanithi, M., Platts, D., Haqqani, H., Thomson, B., Gregory, S., Salamonsen, R. Determination of mechanisms of ventricular interaction responsible for right ventricular failure found with left ventricular assist device implantation. (MS2013-42). The Prince Charles Hospital Foundation. 2013. $86,052.

Gregory, S.D., Timms, D., Thomson, B., Pearcy, M., Fraser, J.F., Liebhardt, A. Development and in-vivo evaluation of a novel inflow cannula for mechanical circulatory support. (MS2013-29). The Prince Charles Hospital Foundation. 2013. $65,300.

Pauls, J.P., Gregory, S.D. Development of a passive physiological control system for ventricular assist devices. (NR2013-222). The Prince Charles Hospital Foundation. 2013. $9,800. 20 th December 2017

Wu, E., Gregory, S.D. Development of a novel physiological control system for rotary blood pumps relating total LVAD and left ventricular work to preload. (NR2013-225). The Prince Charles Hospital Foundation. 2013. $9963.08.

Liao, S., Gregory, S.D. Developing a permanent tissue integration of a suture-less inflow cannula using melt electrospinning technology. (NI2014-127). The Prince Charles Hospital Foundation. 2014. $9995.12.

Ribolzi, C., Gregory, S.D. Flow characteristics of adult aortic cardio-pulmonary bypass cannulae as determined by particle image velocimetry. (NI2014-126). The Prince Charles Hospital Foundation. 2014. $9976.77.

Schummy, E., Gregory, S.D. Design and validation of a compliant, banded outflow cannula for decreasing the after-load sensitivity of rotary right ventricular assist devices. (NI2014-125). The Prince Charles Hospital Foundation. 2014. $9967.37.

Fraser, J.F., Gregory, S.D., Shekar, K., Olive, C., Tansley, G., Platts, D., Tung, J.P., McGiffin, D., Thomson, B., Bull, T. Advanced Cardio-respiratory Therapies Improving OrgaN Support (ACTIONS). (PRO2014-08). The Prince Charles Hospital Foundation. 2014. $599,995.30.

Staib, A., Fraser, J.F., Chan, K., Gregory, S.D., Flaws, D. Adrenaline Delivery through Ventilation of Aerosolised Nanoparticles in Cardiac Arrest (ADVANCE Study). (EMPG-201R21- 2014). Queensland Emergency Medicine Research Foundation. 2014. $250,000.00.

Gregory, S.D., Tansley, G., Timms, D., Masuzawa, T., Fraser, J.F. Development and in-vivo evaluation of a novel biventricular assist device. (MS2014-49). The Prince Charles Hospital Foundation. 2014. $79,644.82.

Bolle, E., Gregory, S.D. Evaluation of ventricular flow dynamics with rotary blood pumps using particle image velocimetry. (NI2014-210). The Prince Charles Hospital Foundation. 2014. $9729.22.

Gromann, K., Gregory, S.D. Development of a less-invasive cannulation system for right ventricular assist devices. (NI2014-206). The Prince Charles Hospital Foundation. 2014. $9998.19

Di Nucci, A., Gregory, S.D. Design and validation of a mock circulation loop for particle image velocimetry evaluation of prosthetic heart valves. (NI2014-213). The Prince Charles Hospital Foundation. 2014. $9989.22

Fraser, J.F., McGiffin, D., Lovell, N., Tansley, G., Pellegrino, V., Roberts, J., Barnett, A., Gregory, S.D. Centre for Research Excellence in Advanced Cardio-respiratory Therapies Improving OrgaN Support (ACTIONS). (APP1079421). National Health and Medical Research Council. 2014. $2,491,450.00

McLachlan, Walsh, Tansley, Cohn, Kofidis, Lyon, Skalsky, Meador, Gregory, Whitbourn. A fully implantable self-powered extra aortic counterpulsation device for translational development in

hypertensive heart failure (APP1093330). National Health and Medical Research Council. 2015. $869,436.00. 20 th December 2017

Gregory, S., Small equipment grant: Dantec Dynamics PIV control system (SEQ2015-12). The Prince Charles Hospital Foundation. 2015. $5,000.00

Obermeier, L., Gregory, S.D. Evaluation of a quick-connect system to reduce ventricular assist device implantation time and complexity (NI2015-131). The Prince Charles Hospital Foundation. 2015. $9779.22

Simmonds, M., Tansley, G., Fraser, J., Grau, M., Gregory, S. Erythrocyte responses to mechanical trauma following exposure to oxidative stress. Griffith University School of Allied Health Sciences Project Grant Scheme. 2015. $10,000.

Vilathgamuwa, M., Gregory, S., Pearcy, M., Fraser, J. Efficient wireless power transfer system for ventricular assist devices (VADs) (ER2015-40). The Prince Charles Hospital Foundation. 2015. $87,769.52.

Gregory, S., Blackwood, K., Fraser, J., Peleg, A., McGiffin, D. Using a bioengineering approach to develop an infection-resistance ventricular assisted device driveline coating (ER2015-14). The Prince Charles Hospital Foundation. 2015. $93,447.00.

Bartnikowski, N., Gregory, S.D. Functional and morphological changes occurring in the left and right ventricles following chronic left ventricular assist device implantation in an ovine model (NI2015-214). The Prince Charles Hospital Foundation. 2015. $9,998.57.

Stephens, A., Gregory, S.D. Low drift fibre bragg grating pressure transducer for use with physiological controllers (NI2015-220). The Prince Charles Hospital Foundation. 2015. $9,951.05.

Jentsch, S., Gregory, S.D. In-vitro optimization of inflow cannula impact to improve blood compatibility (NI2015-207). The Prince Charles Hospital Foundation. 2015. $9,996.52.

Giacoppo, G., Gregory, S.D. The OpenHeart Project (NI2016-124). The Prince Charles Hospital Foundation. 2016. $9875.22.

Girnghuber, A., Gregory, S.D. The effect of varying rotary blood pump speed by modulating frequency on blood compatibility (NI2016-123). The Prince Charles Hospital Foundation. 2016. $9946.89.

Balletti, N., Gregory, S.D. Characterisation of the interaction between blood and an LVAD used for right ventricular support (NI2016-117). The Prince Charles Hospital Foundation. 2016. $9999.89.

Fraser, J.F., Gregory, S.D., Macauley, D., McGiffin, D., Shekar, K., Chan, S., Tansley, G., Platts, D., Barnett, A., Smith, M., Palpant, N., Masuzawa, T. Biomechanical Innovations for cardio-respiratory Organ failure the Next frontier in Critical care (The BIONIC project). Queensland Government. 2016. $1,300,000.

Pauls, J.P., Gregory, S.D., Development and in-vivo evaluation of physiological control systems for a novel, low-cost ventricular assist device ‘OpenHeart’ (EM2016-12). The Prince Charles Hospital Foundation. 2016. $24,783.61. 20 th December 2017

Fraser, J.F., Simmonds, M., Nandakumar, D., Gregory, S.D., Tansley, G. Improving blood-compatibility of extracorporeal membrane oxygenators (ECMO) with nitric oxide (NO) therapy (ER2016-025). The Prince Charles Hospital Foundation. 2016. $99,987.87.

Wilson, S., Rakic, A., Gregory, S., Suen, J. Validation of realtime emboli detection using laser feedback inferferometry (WILSON). The University of Queensland Seed Grant. 2016. $38,318.

Gregory, S.D. Decreasing complications with mechanical hearts through improved implantation techniques (AQRF13716-17RD2). Advance Queensland Research Fellowship. 2017. $180,000.

Boone, A., Gregory, S. Development of a novel intraventricular balloon pump for low cost mechanical circulatory support of patients with left ventricular failure (NI2017-06). The Prince Charles Hospital Foundation. 2017. $9999.42.

Garrick, K., Gregory, S. Optimisation and adaptation of a suture-less cannula for rapid implantation of biventricular assist devices (NI2017-01). The Prince Charles Hospital Foundation. 2017. $9999.96.

Mapley, M., Gregory, S. A low cost bearingless drive for the OpenHeart rotary ventricular assist device (NI2017-28). The Prince Charles Hospital Foundation. 2017. $9875.79.

Garrick, K., Gregory, S., Tansley, G. PhD stipend for suture-less cannula design for rapid implantation of rotary blood pumps (PhD2017-01). The Prince Charles Hospital Foundation. 2017. $80,052.00.

Gregory, S. Partnership support for Advanced Queensland Research Fellowship for decreasing complications with mechanical hearts through improved implantation techniques (CoA-05). The Prince Charles Hospital Foundation. 2017. $75,000.00.

Liao, S., Gregory, S. Refinement of bilayered scaffolds for a novel suture-less inflow cannula for left ventricular assist devices (EM2017-11). The Prince Charles Hospital Foundation. 2017. $24,679.46.

Wu, E., Gregory, S. Talking heart to bionic heart: Towards an intelligent rotary blood pump to improve left ventricular function (EM2017-01). The Prince Charles Hospital Foundation. 2017. $24,973.76.

Gregory, S., Tansley, G., Platts, D., Thomson, B., Chan, C., Pauls, J., Munoz, F., Bartnikowski, N., Strugnell, W., Salamonsen, R., Dargusch, M., Dargaville, T., Li, Z., Wrigley, C., Mullany, D., Steinseifer, U., Lovell, N. Using engineering, biology and medicine to develop the next generation of mechanical circulatory support (TM2017-04). The Prince Charles Hospital Foundation. 2017. $600,000.

Last modified: 30/04/2024