Mr. Avishka Wickramarachchi
Mr. Avishka Wickramarachchi
Qualifications
- Bachelor of Mechanical Engineering (Honours), Monash Univeristy, 2021
- Doctor of Philosophy, Monash University, 2025
Expertise
- Mechanical Circulatory Support
Mechanical devices used to support end-stage cardiac and respiratory dysfunction patients such as extracorporeal membrane oxygenation and left ventricular assist devices.
- Computational Fluid Dynamics
Modelling blood flow within the cardiovascular system by applying transient, turbulence and multiphase models and complex boundary conditions (Windkessel, lumped parameter network, etc) within patient-specific geometries.
Research Interests
I am a postdoctoral research fellow leveraging engineering expertise to improve outcomes of patients suffering from cardiovascular and respiratory diseases. I do this by evaluating blood flow dynamics (computational fluid dynamics), assessing device hemocompatibility (blood circulation loops), and analysing patient hemodynamics (lumped parameter modelling and in vitro benchtop mock circulatory simulators) of novel and existing mechanical circulatory support therapies, ultimately improving and innovating current clinical practice.
- Stephens, A. F., Wickramarachchi, A., Burrell, A. J., Bellomo, R., Raman, J., & Gregory, S. D. (2022). Hemodynamics of small arterial return cannulae for venoarterial extracorporeal membrane oxygenation. Artificial Organs, 46(6), 1068-1076. https://doi.org/10.1111/aor.14179
- Wickramarachchi, A., Burrell, A. J. C., Stephens, A. F., Šeman, M., Vatani, A., Khamooshi, M., Raman, J., Bellomo, R., & Gregory, S. D. (2022). The effect of arterial cannula tip position on differential hypoxemia during venoarterial extracorporeal membrane oxygenation. Phys Eng Sci Med. https://doi.org/10.1007/s13246-022-01203-6
- Wickramarachchi, A., Gregory, S. D., & Khamooshi, M. (2023). Comparison of single-stage and multi-stage drainage cannula flow characteristics during venoarterial extracorporeal membrane oxygenation. Physics of Fluids. https://doi.org/10.1063/5.0137907
- Wickramarachchi, A., Khamooshi, M., Burrell, A., Pellegrino, V. A., Kaye, D. M., & Gregory, S. D. (2023). The effect of drainage cannula tip position on risk of thrombosis during venoarterial extracorporeal membrane oxygenation. Computer Methods and Programs in Biomedicine. https://doi.org/10.1016/j.cmpb.2023.107407
- Joyce, P.R., Hodgson, C., Bellomo, R., Gregory, S. D., Raman, J., Stephens, A., Taylor, K., Paul, E., Wickramarachchi, A., & Burrell, A. (2023). Smaller arterial return cannula diameter during venoarterial extracorporeal membrane oxygenation is not associated with increased haemolysis: A single centre, cohort study. ASAIO Journal. https://www.doi.org/10.1097/MAT.0000000000002027
- Wickramarachchi, A., Gregory, S. D., Burrell, A. J., & Khamooshi, M. (2024). Flow characterization of Maquet and Bio-Medicus multi-stage drainage cannulae during venoarterial extracorporeal membrane oxygenation. Computers in Biology and Medicine, 171, 108135.
- Khamooshi, M., Wickramarachchi, A., Byrne, T., Seman, M., Fletcher, D. F., Burrell, A., & Gregory, S. D. (2024). Blood flow and emboli transport patterns during venoarterial extracorporeal membrane oxygenation: A computational fluid dynamics study. Computers in Biology and Medicine, 172, 108263.
- Wong, Z. Y., Azimi, M., Khamooshi, M., Wickramarachchi, A., Burrell, A., & Gregory, S. D. (2024). The impact of small movements with dual lumen cannulae during venovenous extracorporeal membrane oxygenation: A computational fluid dynamics analysis. Computer Methods and Programs in Biomedicine, 250, 108186.
- Wickramarachchi, A., Burrell, A. J., Joyce, P. R., Bellomo, R., Raman, J., Gregory, S. D., & Stephens, A. F. (2024). Flow capabilities of arterial and drainage cannulae during venoarterial extracorporeal membrane oxygenation: A simulation model. Perfusion.
- Wickramarachchi, A., Shirejini, S. Z., Vatani, A., Rana, A., Khamooshi, M., Šeman, M., Liao, S., Jap, E., Nguyen, T. H., Alt, K., Burrell., A., Pellegrino, V. A., Kaye, D. M., Hagemeyer, C. E., & Gregory, S. D. (2025). Development of a novel drainage cannula for venoarterial extracorporeal membrane oxygenation. ASAIO J.
- Wickramarachchi, A., Wittberg, L.P., Zwischenberger, J., Wang, D., Slaughter, M.S. and Gregory, S.D. (2025). Cannula design. In Mechanical Circulatory and Respiratory Support (pp. 553-590). Academic Press.
- Chand, P., Yusuff, H., Zochios, V., Wickramarachchi, A., Joyce, C., Gregory, S., Shekar, K., & Stephens, A. (2025). Hemodynamic Performance of Veno-Pulmonary ECMO with varying Right Ventricular Function in a Mock Circulatory Loop. ASAIO J.
Teaching Commitments
- ENG1011 - Engineering Methods
- MEC3451 - Fluid Mechanics II