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Jackie and Matthew Wilce Laboratory

Wilce Structural Biology

Welcome to the Jackie and Matthew Wilce Lab

Our research focuses on the biophysical analysis of macromolecular interactions that underlie important cellular processes in health and disease.

We're both part of the Monash Biomedicine Discovery Institute, and members of the Infection and Immunity Program and
the Department of Biochemistry and Molecular Biology.

Professor Jackie Wilce is also a member of the Cancer and Neuroscience Programs.

Professor Jackie Wilce

My global research connections, partners and funding can be viewed on my Monash Research Profile.

If you are a student interested in doing research in our lab, visit Supervisor Connect.

Click the links below to connect with me on ORCID and Google Scholar.

Professor Matthew Wilce

My global research connections, partners and funding can be viewed on my Monash Research Profile.

Click the links below to connect with me on ORCID and Google Scholar.

Our research

Our research focuses on the biophysical analysis of macromolecular interactions that underlie important cellular processes in health and disease. These include protein-nucleotide interactions underlying viral invasion as well as interactions of signalling molecules in cancer. The characterisation of these interactions facilitates the design, synthesis and testing of inhibitor molecules that have therapeutic potential.

  • Protein-RNA interactions in antiviral cellular defence and inflammation

  • Targeting the Grb7 protein involved in cancer progression

Lab members

We are committed to excellence in research.

Wilce Lab members plus friends on Mehdi's thesis submission day

Publications

View our chosen highlighted key publications.

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News

We want to share our research discoveries & successes with you.

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Join Our Lab

We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.

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