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Papa Laboratory

Cancer Biology and Cell Signalling

Welcome to the Papa Lab

Our research focuses on the identification and functional characterisation of novel signalling nodes regulating cell growth and survival and therefore implicated in tumourigenesis and progression to cancer.

We're part of the Monash Biomedicine Discovery Institute, and a member of the Cancer and Metabolism, Diabetes & Obesity and Neuroscience Programs and the Department of Biochemistry and Molecular Biology.

Dr Antonella Papa

My global research connections, partners and funding can be viewed on my Monash Research Profile.

Click the links below to connect with me on ORCID, Google Scholar and LinkedIn.

Our research

Work in the Papa lab focuses on the identification of novel molecular connections that regulate cellular and tissue homeostasis and whose dysfunction contributes to the pathogenesis of cancer. A current interest in our lab is to dissect the role of the PTEN-PI3K axis in breast cancer and the impact that oncogenic alterations in these two essential genes have to tumour evolution. Through omics approaches and in vivo studies our final goal is to identify novel targetable biomarkers that can improve efficacy of PI3K-based therapies for breast cancer treatment.

Figure 1. Cartoon depicting natural tumour evolution.

Lab members

We are committed to excellence in research.

Publications

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News

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Join Our Lab

We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.

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